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Marco Ruella, MD
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Year
Human chimeric antigen receptor macrophages for cancer immunotherapy
M Klichinsky, M Ruella, O Shestova, XM Lu, A Best, M Zeeman, ...
Nature biotechnology 38 (8), 947-953, 2020
14502020
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Cancer discovery 5 (12), 1282-1295, 2015
14262015
Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell
M Ruella, J Xu, DM Barrett, JA Fraietta, TJ Reich, DE Ambrose, ...
Nature medicine 24 (10), 1499-1503, 2018
7222018
Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies
M Ruella, DM Barrett, SS Kenderian, O Shestova, TJ Hofmann, ...
The Journal of clinical investigation 126 (10), 3814-3826, 2016
6732016
Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells
S Gill, SK Tasian, M Ruella, O Shestova, Y Li, DL Porter, M Carroll, ...
Blood, The Journal of the American Society of Hematology 123 (15), 2343-2354, 2014
5772014
Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia
JA Fraietta, KA Beckwith, PR Patel, M Ruella, Z Zheng, DM Barrett, ...
Blood, The Journal of the American Society of Hematology 127 (9), 1117-1127, 2016
5552016
Genetic inactivation of CD33 in hematopoietic stem cells to enable CAR T cell immunotherapy for acute myeloid leukemia
MY Kim, KR Yu, SS Kenderian, M Ruella, S Chen, TH Shin, AA Aljanahi, ...
Cell 173 (6), 1439-1453. e19, 2018
5272018
CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia
SS Kenderian, M Ruella, O Shestova, M Klichinsky, V Aikawa, ...
Leukemia 29 (8), 1637-1647, 2015
5262015
Emerging cellular therapies for cancer
S Guedan, M Ruella, CH June
Annual review of immunology 37 (1), 145-171, 2019
4332019
An NK-like CAR T cell transition in CAR T cell dysfunction
CR Good, MA Aznar, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ...
Cell 184 (25), 6081-6100. e26, 2021
3812021
Catch me if you can: leukemia escape after CD19-directed T cell immunotherapies
M Ruella, MV Maus
Computational and structural biotechnology journal 14, 357-362, 2016
3562016
Five-year outcomes for refractory B-cell lymphomas with CAR T-cell therapy
EA Chong, M Ruella, SJ Schuster
New England Journal of Medicine 384 (7), 673-674, 2021
3552021
Immunogenicity of CAR T cells in cancer therapy
DL Wagner, E Fritsche, MA Pulsipher, N Ahmed, M Hamieh, M Hegde, ...
Nature reviews Clinical oncology 18 (6), 379-393, 2021
3122021
Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses
K Watanabe, Y Luo, T Da, S Guedan, M Ruella, J Scholler, B Keith, ...
JCI insight 3 (7), e99573, 2018
3112018
Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction
N Singh, YG Lee, O Shestova, P Ravikumar, KE Hayer, SJ Hong, XM Lu, ...
Cancer discovery 10 (4), 552-567, 2020
3062020
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy
M Smith, A Dai, G Ghilardi, KV Amelsberg, SM Devlin, R Pajarillo, ...
Nature medicine 28 (4), 713-723, 2022
3032022
T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy
G Ghilardi, JA Fraietta, JN Gerson, VM Van Deerlin, JJD Morrissette, ...
Nature medicine 30 (4), 984-989, 2024
2592024
Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
J Brogdon, E Choi, HE Ebersbach, D Glass, H Huet, CH June, J Mannick, ...
US Patent 10,174,095, 2019
2442019
The Addition of the BTK inhibitor Ibrutinib to anti-CD19 chimeric antigen receptor T cells (CART19) improves responses against mantle cell lymphoma
M Ruella, SS Kenderian, O Shestova, JA Fraietta, S Qayyum, Q Zhang, ...
Clinical Cancer Research 22 (11), 2684-2696, 2016
2192016
Adoptive immunotherapy for cancer
M Ruella, M Kalos
Immunological reviews 257 (1), 14-38, 2014
2102014
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Articles 1–20