| Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility Australo-Anglo-American Spondyloarthritis Consortium (TASC), ... Nature genetics 43 (8), 761-767, 2011 | 1056 | 2011 |
| PD1 signal transduction pathways in T cells H Arasanz, M Gato-Cañas, M Zuazo, M Ibañez-Vea, K Breckpot, ... Oncotarget 8 (31), 51936, 2017 | 364 | 2017 |
| PDL1 signals through conserved sequence motifs to overcome interferon-mediated cytotoxicity M Gato-Cañas, M Zuazo, H Arasanz, M Ibañez-Vea, L Lorenzo, ... Cell reports 20 (8), 1818-1829, 2017 | 347 | 2017 |
| The intracellular signalosome of PD-L1 in cancer cells D Escors, M Gato-Cañas, M Zuazo, H Arasanz, MJ García-Granda, R Vera, ... Signal transduction and targeted therapy 3 (1), 26, 2018 | 327 | 2018 |
| Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming G Kochan, T Krojer, D Harvey, R Fischer, L Chen, M Vollmar, F von Delft, ... Proceedings of the National Academy of Sciences 108 (19), 7745-7750, 2011 | 301 | 2011 |
| Role of severe acute respiratory syndrome coronavirus viroporins E, 3a, and 8a in replication and pathogenesis C Castaño-Rodriguez, JM Honrubia, J Gutiérrez-Álvarez, ML DeDiego, ... MBio 9 (3), 10.1128/mbio. 02325-17, 2018 | 295* | 2018 |
| Understanding LAG-3 signaling L Chocarro, E Blanco, M Zuazo, H Arasanz, A Bocanegra, ... International journal of molecular sciences 22 (10), 5282, 2021 | 224 | 2021 |
| Functional systemic CD 4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy M Zuazo, H Arasanz, G Fernández‐Hinojal, MJ García‐Granda, M Gato, ... EMBO molecular medicine 11 (7), e10293, 2019 | 206 | 2019 |
| Role of non-classical MHC class I molecules in cancer immunosuppression G Kochan, D Escors, K Breckpot, D Guerrero-Setas Oncoimmunology 2 (11), e26491, 2013 | 197 | 2013 |
| Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ... Journal of medicinal chemistry 55 (14), 6639-6643, 2012 | 185 | 2012 |
| Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation DS Froese, G Kochan, JRC Muniz, X Wu, C Gileadi, E Ugochukwu, ... Journal of Biological Chemistry 285 (49), 38204-38213, 2010 | 143 | 2010 |
| Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A G Kochan, ES Pilka, F von Delft, U Oppermann, WW Yue Journal of molecular biology 388 (5), 997-1008, 2009 | 133 | 2009 |
| Structural and mechanistic studies on γ-butyrobetaine hydroxylase IKH Leung, TJ Krojer, GT Kochan, L Henry, F von Delft, TDW Claridge, ... Chemistry & biology 17 (12), 1316-1324, 2010 | 122 | 2010 |
| Crystal structure of the 2-oxoglutarate-and Fe (II)-dependent lysyl hydroxylase JMJD6 M Mantri, T Krojer, EA Bagg, CJ Webby, DS Butler, G Kochan, ... Journal of molecular biology 401 (2), 211-222, 2010 | 121 | 2010 |
| Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis S Ortiz-Espinosa, X Morales, Y Senent, D Alignani, B Tavira, I Macaya, ... Cancer letters 529, 70-84, 2022 | 111 | 2022 |
| Clinical landscape of LAG-3-targeted therapy L Chocarro, E Blanco, H Arasanz, L Fernández-Rubio, A Bocanegra, ... Immuno-Oncology and Technology 14, 100079, 2022 | 104 | 2022 |
| PD-L1 expression in systemic immune cell populations as a potential predictive biomarker of responses to PD-L1/PD-1 blockade therapy in lung cancer A Bocanegra, G Fernandez-Hinojal, M Zuazo-Ibarra, H Arasanz, ... International journal of molecular sciences 20 (7), 1631, 2019 | 91 | 2019 |
| Predictive biomarkers for checkpoint inhibitor immune-related adverse events I Les, M Martinez, I Perez-Francisco, M Cabero, L Teijeira, V Arrazubi, ... Cancers 15 (5), 1629, 2023 | 87 | 2023 |
| Resistance to PD-L1/PD-1 blockade immunotherapy. A tumor-intrinsic or tumor-extrinsic phenomenon? L Chocarro de Erauso, M Zuazo, H Arasanz, A Bocanegra, C Hernandez, ... Frontiers in pharmacology 11, 441, 2020 | 87 | 2020 |
| mRNA vaccines against SARS-CoV-2: Advantages and caveats M Echaide, L Chocarro de Erauso, A Bocanegra, E Blanco, G Kochan, ... International journal of molecular sciences 24 (6), 5944, 2023 | 85 | 2023 |
David Escors Murugarren (ORCID:000...Principal Investigator, NavarraBiomed, University College LondonVerified email at ucl.ac.uk
