| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 12093* | 2021 |
| Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression EJ Park, JH Lee, GY Yu, G He, SR Ali, RG Holzer, CH Österreicher, ... Cell 140 (2), 197-208, 2010 | 2148 | 2010 |
| m6A enhances the phase separation potential of mRNA RJ Ries, S Zaccara, P Klein, A Olarerin-George, S Namkoong, ... Nature 571 (7765), 424-428, 2019 | 731 | 2019 |
| Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies JH Lee, AV Budanov, EJ Park, R Birse, TE Kim, GA Perkins, K Ocorr, ... Science 327 (5970), 1223-1228, 2010 | 672 | 2010 |
| Microscopic examination of spatial transcriptome using Seq-Scope CS Cho, J Xi, Y Si, SR Park, JE Hsu, M Kim, G Jun, HM Kang, JH Lee Cell 184 (13), 3559-3572. e22, 2021 | 496 | 2021 |
| Energy-dependent regulation of cell structure by AMP-activated protein kinase JH Lee, H Koh, M Kim, Y Kim, SY Lee, RE Karess, SH Lee, M Shong, ... Nature 447 (7147), 1017-1020, 2007 | 485 | 2007 |
| Sestrins orchestrate cellular metabolism to attenuate aging JH Lee, AV Budanov, M Karin Cell metabolism 18 (6), 792-801, 2013 | 392 | 2013 |
| Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3 JH Lee, AV Budanov, S Talukdar, EJ Park, HL Park, HW Park, ... Cell metabolism 16 (3), 311-321, 2012 | 347 | 2012 |
| A sestrin-dependent Erk–Jnk–p38 MAPK activation complex inhibits immunity during aging A Lanna, DCO Gomes, B Muller-Durovic, T McDonnell, D Escors, ... Nature immunology 18 (3), 354-363, 2017 | 304 | 2017 |
| Systematic characterization of stress-induced RNA granulation S Namkoong, A Ho, YM Woo, H Kwak, JH Lee Molecular cell 70 (1), 175-187. e8, 2018 | 282 | 2018 |
| Stressin'Sestrins take an aging fight AV Budanov, JH Lee, M Karin EMBO molecular medicine 2 (10), 388-400, 2010 | 271 | 2010 |
| Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay M Kim, E Sandford, D Gatica, Y Qiu, X Liu, Y Zheng, BA Schulman, J Xu, ... elife 5, e12245, 2016 | 256 | 2016 |
| Sestrins induce natural killer function in senescent-like CD8+ T cells BI Pereira, RPH De Maeyer, LP Covre, D Nehar-Belaid, A Lanna, S Ward, ... Nature immunology 21 (6), 684-694, 2020 | 254 | 2020 |
| Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis F Ma, O Plazyo, AC Billi, LC Tsoi, X Xing, R Wasikowski, ... Nature communications 14 (1), 3455, 2023 | 225 | 2023 |
| Sestrin2 inhibits mTORC1 through modulation of GATOR complexes JS Kim, SH Ro, M Kim, HW Park, IA Semple, H Park, US Cho, W Wang, ... Scientific reports 5 (1), 9502, 2015 | 207 | 2015 |
| Hepatoprotective role of Sestrin2 against chronic ER stress HW Park, H Park, SH Ro, I Jang, IA Semple, DN Kim, M Kim, M Nam, ... Nature communications 5 (1), 4233, 2014 | 202 | 2014 |
| Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers HW Park, H Park, IA Semple, I Jang, SH Ro, M Kim, VA Cazares, ... Nature communications 5 (1), 4834, 2014 | 199 | 2014 |
| Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition A Umemura, EJ Park, K Taniguchi, JH Lee, S Shalapour, MA Valasek, ... Cell metabolism 20 (1), 133-144, 2014 | 199 | 2014 |
| Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart A Morrison, L Chen, J Wang, M Zhang, H Yang, Y Ma, A Budanov, JH Lee, ... The FASEB Journal 29 (2), 408, 2014 | 186 | 2014 |
| Magnetically vectored nanocapsules for tumor penetration and remotely switchable on-demand drug release SD Kong, W Zhang, JH Lee, K Brammer, R Lal, M Karin, S Jin Nano letters 10 (12), 5088-5092, 2010 | 183 | 2010 |
Michael KarinProfessor of Pharmacology and Pathology,UCSD,School of MedicineVerified email at ucsd.edu
