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Kevin LITCHFIELD
Kevin LITCHFIELD
Senior Research Leader - Isomorphic Labs (Alphabet company), Honorary Professor - UCL
Verified email at google.com
Title
Cited by
Cited by
Year
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis
S Turajlic, K Litchfield, H Xu, R Rosenthal, N McGranahan, JL Reading, ...
The lancet oncology 18 (8), 1009-1021, 2017
10442017
Tracking cancer evolution reveals constrained routes to metastases: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, T Chambers, JI Lopez, D Nicol, ...
Cell 173 (3), 581-594. e12, 2018
8922018
Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition
K Litchfield, JL Reading, C Puttick, K Thakkar, C Abbosh, R Bentham, ...
Cell 184 (3), 596-614. e14, 2021
8742021
Lung adenocarcinoma promotion by air pollutants
W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ...
Nature 616 (7955), 159-167, 2023
7232023
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ...
Cell 173 (3), 595-610. e11, 2018
7072018
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer cell 33 (4), 649-663. e4, 2018
6802018
Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
PC Haycock, S Burgess, A Nounu, J Zheng, GN Okoli, J Bowden, ...
JAMA oncology 3 (5), 636-651, 2017
6262017
Timing the landmark events in the evolution of clear cell renal cell cancer: TRACERx renal
TJ Mitchell, S Turajlic, A Rowan, D Nicol, JHR Farmery, T O’Brien, ...
Cell 173 (3), 611-623. e17, 2018
5842018
UVB-induced tumor heterogeneity diminishes immune response in melanoma
Y Wolf, O Bartok, S Patkar, GB Eli, S Cohen, K Litchfield, R Levy, ...
Cell 179 (1), 219-235. e21, 2019
4222019
Pervasive chromosomal instability and karyotype order in tumour evolution
TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ...
Nature 587 (7832), 126-132, 2020
3902020
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
Y Chu, E Dai, Y Li, G Han, G Pei, DR Ingram, K Thakkar, JJ Qin, M Dang, ...
Nature medicine 29 (6), 1550-1562, 2023
3452023
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA
C Abbosh, AM Frankell, T Harrison, J Kisistok, A Garnett, L Johnson, ...
Nature 616 (7957), 553-562, 2023
3302023
Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death
MS Ricci, SH Kim, K Ogi, JP Plastaras, J Ling, W Wang, Z Jin, YY Liu, ...
Cancer cell 12 (1), 66-80, 2007
3212007
Cancer evolution: Darwin and beyond
R Vendramin, K Litchfield, C Swanton
The EMBO Journal 40 (18), e108389, 2021
2822021
Metastasis and immune evasion from extracellular cGAMP hydrolysis
J Li, MA Duran, N Dhanota, WK Chatila, SE Bettigole, J Kwon, RK Sriram, ...
Cancer discovery 11 (5), 1212-1227, 2021
2812021
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma
L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ...
Cancer cell 39 (11), 1497-1518. e11, 2021
2542021
Antibodies against endogenous retroviruses promote lung cancer immunotherapy
KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ...
Nature 616 (7957), 563-573, 2023
2532023
Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours
K Litchfield, B Summersgill, S Yost, R Sultana, K Labreche, D Dudakia, ...
Nature communications 6 (1), 5973, 2015
2162015
9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy
G Han, G Yang, D Hao, Y Lu, K Thein, BS Simpson, J Chen, R Sun, ...
Nature communications 12 (1), 5606, 2021
2042021
Genomic–transcriptomic evolution in lung cancer and metastasis
C Martínez-Ruiz, JRM Black, C Puttick, MS Hill, J Demeulemeester, ...
Nature 616 (7957), 543-552, 2023
1922023
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Articles 1–20