| Uncovering disease-disease relationships through the incomplete interactome J Menche, A Sharma, M Kitsak, SD Ghiassian, M Vidal, J Loscalzo, ... Science 347 (6224), 1257601, 2015 | 1689 | 2015 |
| A proteome-scale map of the human interactome network T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ... Cell 159 (5), 1212-1226, 2014 | 1607 | 2014 |
| Human symptoms–disease network XZ Zhou, J Menche, AL Barabási, A Sharma Nature communications 5 (1), 4212, 2014 | 760 | 2014 |
| Canonical Genetic Signatures of the Adult Human Brain M Hawrylycz, JA Miller, V Menon, D Feng, T Dolbeare, ... Nature Neuroscience, 2015 | 749 | 2015 |
| Network-based in silico drug efficacy screening E Guney, J Menche, M Vidal, AL Barábasi Nature communications 7 (1), 10331, 2016 | 637 | 2016 |
| A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome SD Ghiassian, J Menche, AL Barabási PLoS computational biology 11 (4), e1004120, 2015 | 477 | 2015 |
| Assessment of network module identification across complex diseases S Choobdar, ME Ahsen, J Crawford, M Tomasoni, T Fang, D Lamparter, ... Nature methods 16 (9), 843-852, 2019 | 358 | 2019 |
| A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma A Sharma, J Menche, CC Huang, T Ort, X Zhou, M Kitsak, N Sahni, ... Human molecular genetics 24 (11), 3005-3020, 2015 | 235 | 2015 |
| Network medicine: complex systems in human disease and therapeutics EM Antman, MA Calderwood, B Charloteaux, CB Clish, ME Cusick, ... Harvard University Press, 2017 | 155 | 2017 |
| Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers S Schick, AF Rendeiro, K Runggatscher, A Ringler, B Boidol, M Hinkel, ... Nature genetics 51 (9), 1399-1410, 2019 | 152 | 2019 |
| Interactome-based approaches to human disease M Caldera, P Buphamalai, F Müller, J Menche Current Opinion in Systems Biology 3, 88-94, 2017 | 123 | 2017 |
| Tissue specificity of human disease module M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, ... Scientific reports 6 (1), 35241, 2016 | 123 | 2016 |
| Type I interferon signaling disrupts the hepatic urea cycle and alters systemic metabolism to suppress T cell function A Lercher, A Bhattacharya, AM Popa, M Caldera, MF Schlapansky, ... Immunity 51 (6), 1074-1087. e9, 2019 | 121 | 2019 |
| Plasticity of the cullin-RING ligase repertoire shapes sensitivity to ligand-induced protein degradation C Mayor-Ruiz, MG Jaeger, S Bauer, M Brand, C Sin, A Hanzl, AC Mueller, ... Molecular cell 75 (4), 849-858. e8, 2019 | 119 | 2019 |
| Endophenotype network models: common core of complex diseases SD Ghiassian, J Menche, DI Chasman, F Giulianini, R Wang, P Ricchiuto, ... Scientific reports 6 (1), 27414, 2016 | 99 | 2016 |
| Network analysis reveals rare disease signatures across multiple levels of biological organization P Buphamalai, T Kokotovic, V Nagy, J Menche Nature communications 12 (1), 6306, 2021 | 94 | 2021 |
| MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation S Sdelci, AF Rendeiro, P Rathert, W You, JMG Lin, A Ringler, G Hofstätter, ... Nature genetics 51 (6), 990-998, 2019 | 91 | 2019 |
| Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms F Schischlik, R Jäger, F Rosebrock, E Hug, M Schuster, R Holly, E Fuchs, ... Blood, The Journal of the American Society of Hematology 134 (2), 199-210, 2019 | 81 | 2019 |
| Non-classical monocytes as mediators of tissue destruction in arthritis A Puchner, V Saferding, M Bonelli, Y Mikami, M Hofmann, JS Brunner, ... Annals of the rheumatic diseases 77 (10), 1490-1497, 2018 | 81 | 2018 |
| B cell–activating factor neutralization aggravates atherosclerosis D Tsiantoulas, AP Sage, L Göderle, M Ozsvar-Kozma, D Murphy, ... Circulation 138 (20), 2263-2273, 2018 | 76 | 2018 |
Albert-László BarabásiNortheastern University, Harvard Medical School, Central European UniversityVerified email at neu.edu
