| Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ... Cell stem cell 20 (2), 233-246. e7, 2017 | 597 | 2017 |
| Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo FJ Najm, M Madhavan, A Zaremba, E Shick, RT Karl, DC Factor, TE Miller, ... Nature 522 (7555), 216-220, 2015 | 488 | 2015 |
| Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells FJ Najm, AM Lager, A Zaremba, K Wyatt, AV Caprariello, DC Factor, ... Nature biotechnology 31 (5), 426-433, 2013 | 343 | 2013 |
| Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens FJ Najm, C Strand, KF Donovan, M Hegde, KR Sanson, EW Vaimberg, ... Nature biotechnology 36 (2), 179-189, 2018 | 337 | 2018 |
| Isolation of epiblast stem cells from preimplantation mouse embryos FJ Najm, JG Chenoweth, PD Anderson, JH Nadeau, RW Redline, ... Cell stem cell 8 (3), 318-325, 2011 | 186 | 2011 |
| Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells FJ Najm, A Zaremba, AV Caprariello, S Nayak, EC Freundt, PC Scacheri, ... Nature methods 8 (11), 957-962, 2011 | 110 | 2011 |
| Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements S Battaglia, K Dong, J Wu, Z Chen, FJ Najm, Y Zhang, MM Moore, ... Nature Genetics, 1-10, 2022 | 64 | 2022 |
| Cell type-specific intralocus interactions reveal oligodendrocyte mechanisms in MS DC Factor, AM Barbeau, KC Allan, LR Hu, M Madhavan, AT Hoang, ... Cell 181 (2), 382-395. e21, 2020 | 56 | 2020 |
| Diverse chemical scaffolds enhance oligodendrocyte formation by inhibiting CYP51, TM7SF2, or EBP D Allimuthu, Z Hubler, FJ Najm, H Tang, I Bederman, W Seibel, PJ Tesar, ... Cell chemical biology 26 (4), 593-599. e4, 2019 | 41 | 2019 |
| Differentiation method for production of glial cell populations PJ Tesar, RH Miller, FJ Najm US Patent 9,193,951, 2015 | 19 | 2015 |
| Integrative dissection of gene regulatory elements at base resolution Z Chen, NM Javed, M Moore, J Wu, ME Vinyard, L Pinello, F Najm, ... bioRxiv, 2022 | 16 | 2022 |
| Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma SM Bevill, S Casaní-Galdón, CA El Farran, EG Cytrynbaum, KA Macias, ... Cell Genomics, 2023 | 12 | 2023 |
| Chromatin complex dependencies reveal targeting opportunities in leukemia FJ Najm, P DeWeirdt, MM Moore, SM Bevill, CA El Farran, KA Macias, ... Nature Communications 14 (1), 448, 2023 | 12 | 2023 |
| Glial cells and oligodendrocytes produced by reprogramming somatic cells with Sox10, Olig2 and Nkx6. 2 PJ Tesar, RH Miller, FJ Najm US Patent 9,487,757, 2016 | 12 | 2016 |
| Generation and characterization of epiblast stem cells from blastocyst-stage mouse embryos DC Factor, FJ Najm, PJ Tesar Epiblast Stem Cells, 1-13, 2013 | 9 | 2013 |
| Depletion of Olig2 in oligodendrocyte progenitor cells infected by Theiler’s murine encephalomyelitis virus B Benner, AJ Martorell, P Mahadevan, FJ Najm, PJ Tesar, EC Freundt Journal of neurovirology 22 (3), 336-348, 2016 | 8 | 2016 |
| Method of promoting remyelination P Tesar, FJ Najm, RH Miller US Patent 10,195,194, 2019 | 5 | 2019 |
| Renewing your HBO1 subscription FJ Najm, P van Galen Blood, The Journal of the American Society of Hematology 139 (6), 802-804, 2022 | 3 | 2022 |
| Differntiation method for production of glial cell population PJ Tesar, RH Miller, FJ Najm US Patent 9,969,974, 2018 | 3 | 2018 |
| Multi-locus CRISPRi targeting with a single truncated guide RNA MM Moore, S Wekhande, R Issner, A Collins, Y Liu, N Javed, ... bioRxiv, 2023.10. 20.563306, 2023 | 2 | 2023 |
