| Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs Ö Babur, AR Melrose, JM Cunliffe, J Klimek, J Pang, ALI Sepp, ... Blood, The Journal of the American Society of Hematology 136 (20), 2346-2358, 2020 | 85 | 2020 |
| Toll-like receptors, inflammation, and calcific aortic valve disease C García-Rodríguez, I Parra-Izquierdo, I Castaños-Mollor, J López, ... Frontiers in physiology 9, 201, 2018 | 81 | 2018 |
| Lipopolysaccharide and interferon-γ team up to activate HIF-1α via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells I Parra-Izquierdo, I Castaños-Mollor, J López, C Gómez, JA San Román, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (9 …, 2019 | 73 | 2019 |
| Calcification induced by type I interferon in human aortic valve interstitial cells is larger in males and blunted by a janus kinase inhibitor I Parra-Izquierdo, I Castaños-Mollor, J López, C Gómez, JA San Román, ... Arteriosclerosis, Thrombosis, and Vascular Biology 38 (9), 2148-2159, 2018 | 69 | 2018 |
| The toll-like receptor 2 ligand Pam2CSK4 activates platelet nuclear factor-κB and Bruton’s tyrosine kinase signaling to promote platelet-endothelial cell interactions I Parra-Izquierdo, HHS Lakshmanan, AR Melrose, J Pang, TJ Zheng, ... Frontiers in Immunology 12, 729951, 2021 | 32 | 2021 |
| CRISPR-edited megakaryocytes for rapid screening of platelet gene functions E Montenont, S Bhatlekar, S Jacob, Y Kosaka, BK Manne, O Lee, ... Blood Advances 5 (9), 2362-2374, 2021 | 29 | 2021 |
| Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function I Parra-Izquierdo, AR Melrose, J Pang, HHS Lakshmanan, SE Reitsma, ... Platelets 33 (3), 404-415, 2022 | 24 | 2022 |
| Platelets and tyrosine kinase inhibitors: clinical features, mechanisms of action, and effects on physiology TJ Zheng, I Parra-Izquierdo, SE Reitsma, MC Heinrich, MK Larson, ... American Journal of Physiology-Cell Physiology 323 (4), C1231-C1250, 2022 | 21 | 2022 |
| Rho GTPase regulation of reactive oxygen species generation and signalling in platelet function and disease ATP Ngo, I Parra-Izquierdo, JE Aslan, OJT McCarty Small GTPases 12 (5-6), 440-457, 2021 | 21 | 2021 |
| Interferons are pro-inflammatory cytokines in sheared-stressed human aortic valve endothelial cells I Parra-Izquierdo, T Sánchez-Bayuela, J López, C Gómez, ... International journal of molecular sciences 22 (19), 10605, 2021 | 21 | 2021 |
| Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity TJ Zheng, TCL Kohs, PA Mueller, J Pang, SE Reitsma, I Parra-Izquierdo, ... Blood Advances 7 (8), 1366-1378, 2023 | 19 | 2023 |
| Perspectives on platelet heterogeneity and host immune response in coronavirus disease 2019 (COVID-19) I Parra-Izquierdo, JE Aslan Seminars in thrombosis and hemostasis 46 (07), 826-830, 2020 | 18 | 2020 |
| Clinically used JAK inhibitor blunts dsRNA‐induced inflammation and calcification in aortic valve interstitial cells I Parra‐Izquierdo, T Sánchez‐Bayuela, I Castaños‐Mollor, J López, ... The FEBS Journal 288 (22), 6528-6542, 2021 | 17 | 2021 |
| Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function SE Reitsma, HHS Lakshmanan, J Johnson, J Pang, I Parra-Izquierdo, ... American Journal of Physiology-Cell Physiology 322 (3), C370-C381, 2022 | 16 | 2022 |
| Activation of coagulation FXI promotes endothelial inflammation and amplifies platelet activation in a nonhuman primate model of hyperlipidemia TCL Kohs, HH Vu, KR Jordan, I Parra-Izquierdo, MT Hinds, JJ Shatzel, ... Research and Practice in Thrombosis and Haemostasis 8 (1), 102276, 2024 | 14 | 2024 |
| Thrombin generation and activity in multiple sclerosis KR Jordan, I Parra-Izquierdo, A Gruber, JJ Shatzel, P Pham, LS Sherman, ... Metabolic brain disease 36 (3), 407-420, 2021 | 14 | 2021 |
| Platelet miR-223 delivery rescues vascular cells in Kawasaki disease I Parra-Izquierdo, OJT McCarty, JE Aslan Circulation research 127 (7), 874-876, 2020 | 13 | 2020 |
| Inflammation via JAK-STAT/HIF-1α drives metabolic changes in pentose phosphate pathway and glycolysis that support aortic valve cell calcification T Sánchez-Bayuela, M Peral-Rodrigo, I Parra-Izquierdo, J López, ... Arteriosclerosis, Thrombosis, and Vascular Biology 45 (7), e232-e249, 2025 | 7 | 2025 |
| Platelets get gutted by PAG I Parra-Izquierdo, R Bradley, JE Aslan Platelets 31 (5), 618-620, 2020 | 7 | 2020 |
| Pharmacological effects of small molecule BCR-ABL tyrosine kinase inhibitors on platelet function Y Zhang, CJ Yang, AR Melrose, J Pang, K Schofield, SD Song, ... The Journal of pharmacology and experimental therapeutics 392 (1), 100020, 2025 | 6 | 2025 |
