| The human transcription factors SA Lambert, A Jolma, LF Campitelli, PK Das, Y Yin, M Albu, X Chen, ... Cell 172 (4), 650-665, 2018 | 4033 | 2018 |
| The Hedgehog and Wnt signalling pathways in cancer J Taipale, PA Beachy nature 411 (6835), 349-354, 2001 | 1983 | 2001 |
| Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins MJ Karkkainen, P Haiko, K Sainio, J Partanen, J Taipale, TV Petrova, ... Nature immunology 5 (1), 74-80, 2004 | 1921 | 2004 |
| Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened JK Chen, J Taipale, MK Cooper, PA Beachy Genes & development 16 (21), 2743-2748, 2002 | 1890 | 2002 |
| Effects of oncogenic mutations in Smoothenedand Patched can be reversed by cyclopamine J Taipale, JK Chen, MK Cooper, B Wang, RK Mann, L Milenkovic, ... Nature 406, 1005-1009, 2000 | 1656 | 2000 |
| Hedgehog: functions and mechanisms M Varjosalo, J Taipale Genes & development 22 (18), 2454-2472, 2008 | 1570 | 2008 |
| DNA-Binding Specificities of Human Transcription Factors A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ... Cell 152 (1), 327-339, 2013 | 1558 | 2013 |
| CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response E Haapaniemi, S Botla, J Persson, B Schmierer, J Taipale Nature medicine 24 (7), 927-930, 2018 | 1479 | 2018 |
| Counting absolute numbers of molecules using unique molecular identifiers T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ... Nature methods 9 (1), 72-74, 2012 | 1461 | 2012 |
| Impact of cytosine methylation on DNA binding specificities of human transcription factors Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, ... Science 356 (6337), eaaj2239, 2017 | 1414 | 2017 |
| Growth factors in the extracellular matrix J Taipale, J Keski‐Oja The FASEB Journal 11 (1), 51-59, 1997 | 1278 | 1997 |
| Cardiovascular failure in mouse embryos deficient in VEGF receptor-3 DJ Dumont, L Jussila, J Taipale, A Lymboussaki, T Mustonen, K Pajusola, ... Science 282 (5390), 946-949, 1998 | 1217 | 1998 |
| Small molecule modulation of Smoothened activity JK Chen, J Taipale, KE Young, T Maiti, PA Beachy Proceedings of the National Academy of Sciences 99 (22), 14071-14076, 2002 | 1200 | 2002 |
| Patched acts catalytically to suppress the activity of Smoothened J Taipale, MK Cooper, T Maiti, PA Beachy Nature 418 (6900), 892-896, 2002 | 1082 | 2002 |
| Medulloblastoma growth inhibition by hedgehog pathway blockade DM Berman, SS Karhadkar, AR Hallahan, JI Pritchard, CG Eberhart, ... Science 297 (5586), 1559, 2002 | 1054 | 2002 |
| MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ... Science 334 (6053), 252-255, 2011 | 827 | 2011 |
| VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer R Valtola, P Salven, P Heikkilä, J Taipale, H Joensuu, M Rehn, ... The American journal of pathology 154 (5), 1381-1390, 1999 | 781 | 1999 |
| Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ... The EMBO journal 29 (13), 2147, 2010 | 721 | 2010 |
| DNA-dependent formation of transcription factor pairs alters their binding specificity A Jolma, Y Yin, KR Nitta, K Dave, A Popov, M Taipale, M Enge, T Kivioja, ... Nature 527 (7578), 384-388, 2015 | 673 | 2015 |
| Minimizing the risk of reporting false positives in large-scale RNAi screens CJ Echeverri, PA Beachy, B Baum, M Boutros, F Buchholz, SK Chanda, ... Nature methods 3 (10), 777-779, 2006 | 640 | 2006 |
Arttu JolmaResearch Associate at University of TorontoVerified email at utoronto.ca
