| Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing AV Anzalone*, XD Gao*, CJ Podracky*, AT Nelson, LW Koblan, ... Nature biotechnology 40 (5), 731-740, 2022 | 596 | 2022 |
| Phage-assisted evolution and protein engineering yield compact, efficient prime editors JL Doman*, S Pandey*, ME Neugebauer, M An, JR Davis, PB Randolph, ... Cell 186 (18), 3983-4002. e26, 2023 | 259 | 2023 |
| Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing Y Xu, XD Gao, JH Lee, H Huang, H Tan, J Ahn, LM Reinke, ME Peter, ... Genes & Development, 1191-1203, 2014 | 256 | 2014 |
| CD44 splice isoform switching determines breast cancer stem cell state H Zhang, RL Brown, Y Wei, P Zhao, S Liu, X Liu, Y Deng, X Hu, J Zhang, ... Genes & Development 33 (3-4), 166-179, 2019 | 237 | 2019 |
| NmeCas9 is an intrinsically high-fidelity genome-editing platform N Amrani*, XD Gao*, P Liu, A Edraki, A Mir, R Ibraheim, A Gupta, ... Genome Biology 19 (1), 214, 2018 | 168 | 2018 |
| C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2 XD Gao, LC Tu, A Mir, T Rodriguez, Y Ding, J Leszyk, J Dekker, ... Nature methods 15 (6), 433-436, 2018 | 161 | 2018 |
| Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing S Pandey*, XD Gao*, NA Krasnow, A McElroy, YA Tao, JE Duby, ... Nature Biomedical Engineering 9 (1), 22-39, 2024 | 140 | 2024 |
| Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 Anti-CRISPR proteins J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ... MBio 9 (6), e02321-18, 2018 | 106 | 2018 |
| In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration EH Choi*, S Suh*, AT Foik, H Leinonen, GA Newby, XD Gao, S Banskota, ... Nature communications 13 (1), 1830, 2022 | 93 | 2022 |
| Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT SE Harvey, Y Xu, X Lin, XD Gao, Y Qiu, J Ahn, X Xiao, C Cheng Rna 24 (10), 1326-1338, 2018 | 84 | 2018 |
| Adenine Base Editing In Vivo with a Single Adeno-Associated Virus Vector H Zhang, N Bamidele, P Liu, O Ojelabi, XD Gao, T Rodriguez, H Cheng, ... GEN biotechnology 1 (3), 285-299, 2022 | 66 | 2022 |
| Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence David R Liu, Andrew Vito Anzalone, Jonathan Ma Levy, Xin Gao, Christopher J ... US Patent US11912985B2, 2023 | 29* | 2023 |
| Prime editing: current advances and therapeutic opportunities in human diseases Y Fu*, X He*, XD Gao*, F Li, S Ge, Z Yang, X Fan Science Bulletin, 2023 | 26 | 2023 |
| Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases AV Anzalone*, XD Gao*, CJ Podracky*, AT Nelson, LW Koblan, ... Biorxiv, 2021.11. 01.466790, 2021 | 16 | 2021 |
| In vivo prime editing rescues photoreceptor degeneration in nonsense mutant retinitis pigmentosa Y Fu, X He, L Ma, XD Gao, P Liu, H Shi, P Chai, S Ge, R Jia, DR Liu, ... Nature Communications 16 (1), 2394, 2025 | 14 | 2025 |
| Twin prime editing mediated exon skipping/reinsertion for restored collagen VII expression in recessive dystrophic epidermolysis bullosa BJ Steinbeck*, XD Gao*, AN McElroy, S Pandey, JL Doman, MJ Riddle, ... Journal of Investigative Dermatology, 2024 | 10 | 2024 |
| Adapting dCas9-APEX2 for subnuclear proteomic profiling XD Gao, TC Rodríguez, EJ Sontheimer Methods in Enzymology 616, 365-383, 2019 | 9 | 2019 |
| Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome NO Abutaleb, XD Gao, A Bedapudi, L Choi, KL Shores, C Kennedy, ... APL bioengineering 9 (1), 2025 | 1 | 2025 |
| Evolved recombinases for editing a genome in combination with prime editing DR Liu, S Pandey, X Gao WO Patent App. WO2024168147A3, 2024 | | 2024 |
| Methods and compositions for modulating cellular factors to increase prime editing efficiencies DR Liu, PJ Chen, X Gao WO Patent App. WO2024138087A2, 2024 | | 2024 |
