| Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth L Zhang, S Zhang, J Yao, FJ Lowery, Q Zhang, WC Huang, P Li, M Li, ... Nature 527 (7576), 100-104, 2015 | 1328 | 2015 |
| JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species HM Shen, Z Liu Free Radical Biology and Medicine 40 (6), 928-939, 2006 | 782 | 2006 |
| Suggestive annotation: A deep active learning framework for biomedical image segmentation L Yang, Y Zhang, J Chen, S Zhang, DZ Chen International conference on medical image computing and computer-assisted …, 2017 | 689 | 2017 |
| Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways S Zhang, WC Huang, P Li, H Guo, SB Poh, SW Brady, Y Xiong, LM Tseng, ... Nature medicine 17 (4), 461-469, 2011 | 648 | 2011 |
| Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells S Zhang, CN Ong, HM Shen Cancer letters 208 (2), 143-153, 2004 | 567 | 2004 |
| Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms S Zhang, YK Won, CN Ong, HM Shen Current Medicinal Chemistry-Anti-Cancer Agents 5 (3), 239-249, 2005 | 541 | 2005 |
| Targeting Src family kinases in anti-cancer therapies: turning promise into triumph S Zhang, D Yu Trends in pharmacological sciences 33 (3), 122-128, 2012 | 402 | 2012 |
| PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer FJ Esteva, H Guo, S Zhang, C Santa-Maria, S Stone, JS Lanchbury, ... The American journal of pathology 177 (4), 1647-1656, 2010 | 389 | 2010 |
| PI (3) King Apart PTEN's Role in CancerPTEN Deficiency and Cancer S Zhang, D Yu Clinical Cancer Research 16 (17), 4325-4330, 2010 | 355 | 2010 |
| Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer DN Edwards, VM Ngwa, AL Raybuck, S Wang, Y Hwang, LC Kim, SH Cho, ... The Journal of clinical investigation 131 (4), 2021 | 337 | 2021 |
| A poisson-gaussian denoising dataset with real fluorescence microscopy images Y Zhang, Y Zhu, E Nichols, Q Wang, S Zhang, C Smith, S Howard Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern …, 2019 | 289 | 2019 |
| Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy PK Morrow, GM Wulf, J Ensor, DJ Booser, JA Moore, PR Flores, Y Xiong, ... Journal of Clinical Oncology 29 (23), 3126, 2011 | 266 | 2011 |
| Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells J Zhou, S Zhang, O Choon-Nam, HM Shen Biochemical pharmacology 72 (2), 132-144, 2006 | 241 | 2006 |
| CNS-native myeloid cells drive immune suppression in the brain metastatic niche through Cxcl10 IH Guldner, Q Wang, L Yang, SM Golomb, Z Zhao, JA Lopez, A Brunory, ... Cell 183 (5), 1234-1248. e25, 2020 | 156 | 2020 |
| Suppressed NF-κB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-α-induced apoptosis in human cancer cells S Zhang, ZN Lin, CF Yang, X Shi, CN Ong, HM Shen Carcinogenesis 25 (11), 2191-2199, 2004 | 155 | 2004 |
| Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin J Zhou, CN Ong, GM Hur, HM Shen Biochemical pharmacology 79 (9), 1242-1250, 2010 | 139 | 2010 |
| SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases S Zhang, WC Huang, L Zhang, C Zhang, FJ Lowery, Z Ding, H Guo, ... Cancer research 73 (18), 5764-5774, 2013 | 136 | 2013 |
| Stromal cell-laden 3D hydrogel microwell arrays as tumor microenvironment model for studying stiffness dependent stromal cell-cancer interactions X Yue, TD Nguyen, V Zellmer, S Zhang, P Zorlutuna Biomaterials 170, 37-48, 2018 | 119 | 2018 |
| Involvement of proapoptotic Bcl-2 family members in parthenolide-induced mitochondrial dysfunction and apoptosis S Zhang, CN Ong, HM Shen Cancer letters 211 (2), 175-188, 2004 | 119 | 2004 |
| Evolving concepts of tumor heterogeneity VR Zellmer, S Zhang Cell & bioscience 4 (1), 1-8, 2014 | 116 | 2014 |
Han-Ming ShenUniversity of MacauVerified email at umac.mo
