| Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining BL Mahaney, K Meek, SP Lees-Miller Biochemical Journal 417 (3), 639-650, 2009 | 1022 | 2009 |
| DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product KO Hartley, D Gell, GCM Smith, H Zhang, N Divecha, MA Connelly, ... Cell 82 (5), 849-856, 1995 | 943 | 1995 |
| GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase SP Jackson, JJ MacDonald, S Lees-Miller, R Tjian Cell 63 (1), 155-165, 1990 | 843 | 1990 |
| ATM associates with and phosphorylates p53: mapping the region of interaction KE Keating, S Kozlov, S Scott, M Gatei, K Hobson, Y Taya, B Gabrielli, ... Nature genetics 20 (4), 398-400, 1998 | 678 | 1998 |
| DNA damage-induced activation of ATM and ATM-dependent signaling pathways EU Kurz, SP Lees-Miller DNA repair 3 (8-9), 889-900, 2004 | 675 | 2004 |
| Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53 SP Lees-Miller, K Sakaguchi, SJ Ullrich, E Appella, CW Anderson Molecular and cellular biology 12 (11), 5041-5049, 1992 | 674 | 1992 |
| Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line SP Lees-Miller, R Godbout, DW Chan, M Weinfeld, RS Day III, GM Barron, ... Science 267 (5201), 1183-1185, 1995 | 647 | 1995 |
| Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen SP Lees-Miller, YR Chen, CW Anderson Molecular and cellular biology 10 (12), 6472-6481, 1990 | 554 | 1990 |
| Repair of DNA double strand breaks by non-homologous end joining SP Lees-Miller, K Meek Biochimie 85 (11), 1161-1173, 2003 | 542 | 2003 |
| DNA‐PK autophosphorylation facilitates Artemis endonuclease activity AA Goodarzi, Y Yu, E Riballo, P Douglas, SA Walker, R Ye, C Härer, ... The EMBO journal 25 (16), 3880-3889, 2006 | 511 | 2006 |
| DNA‐dependent protein kinase catalytic subunit: a target for an ICE‐like protease in apoptosis. Q Song, SP Lees‐Miller, S Kumar, Z Zhang, DW Chan, GC Smith, ... The EMBO journal 15 (13), 3238-3246, 1996 | 479 | 1996 |
| DNA-dependent protein kinase acts upstream of p53 in response to DNA damage RA Woo, KG McLure, SP Lees-Miller, DE Rancourt, PWK Lee Nature 394 (6694), 700-704, 1998 | 456 | 1998 |
| ATM mediates phosphorylation at multiple p53 sites, including Ser46, in response to ionizing radiation S Saito, AA Goodarzi, Y Higashimoto, Y Noda, SP Lees-Miller, E Appella, ... Journal of Biological Chemistry 277 (15), 12491-12494, 2002 | 437 | 2002 |
| Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair Q Ding, YVR Reddy, W Wang, T Woods, P Douglas, DA Ramsden, ... Molecular and cellular biology 23 (16), 5836-5848, 2003 | 434 | 2003 |
| Structure of the RPA trimerization core and its role in the multistep DNA‐binding mechanism of RPA E Bochkareva, S Korolev, SP Lees‐Miller, A Bochkarev The EMBO journal, 2002 | 428 | 2002 |
| DNA-PK: the means to justify the ends? K Meek, V Dang, SP Lees-Miller Advances in immunology 99, 33-58, 2008 | 401 | 2008 |
| The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit (∗) DW Chan, SP Lees-Miller Journal of Biological Chemistry 271 (15), 8936-8941, 1996 | 389 | 1996 |
| Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice X Cui, Y Yu, S Gupta, YM Cho, SP Lees-Miller, K Meek Molecular and cellular biology 25 (24), 10842-10852, 2005 | 367 | 2005 |
| The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis N Jette, SP Lees-Miller Progress in biophysics and molecular biology 117 (2-3), 194-205, 2015 | 356 | 2015 |
| Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A AA Goodarzi, JC Jonnalagadda, P Douglas, D Young, R Ye, ... The EMBO journal 23 (22), 4451, 2004 | 351 | 2004 |
