| Dopamine is a regulator of arousal in the fruit fly K Kume, S Kume, SK Park, J Hirsh, FR Jackson Journal of Neuroscience 25 (32), 7377-7384, 2005 | 668 | 2005 |
| Insulin staining of ES cell progeny from insulin uptake J Rajagopal, WJ Anderson, S Kume, OI Martinez, DA Melton Science 299 (5605), 363-363, 2003 | 649 | 2003 |
| Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells N Shiraki, Y Shiraki, T Tsuyama, F Obata, M Miura, G Nagae, H Aburatani, ... Cell metabolism 19 (5), 780-794, 2014 | 601 | 2014 |
| The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos T Saneyoshi, S Kume, Y Amasaki, K Mikoshiba Nature 417 (6886), 295-299, 2002 | 453 | 2002 |
| Identification of a dopamine pathway that regulates sleep and arousal in Drosophila T Ueno, J Tomita, H Tanimoto, K Endo, K Ito, S Kume, K Kume Nature neuroscience 15 (11), 1516-1523, 2012 | 359 | 2012 |
| The Xenopus IP3 receptor: structure, function, and localization in oocytes and eggs S Kume, A Muto, J Aruga, T Nakagawa, T Michikawa, T Furuichi, ... Cell 73 (3), 555-570, 1993 | 260 | 1993 |
| Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3—deficient mice M Ohmuraya, M Hirota, M Araki, N Mizushima, M Matsui, T Mizumoto, ... Gastroenterology 129 (2), 696-705, 2005 | 204 | 2005 |
| Activation of the G protein Gq/11 through tyrosine phosphorylation of the α subunit H Umemori, T Inoue, S Kume, N Sekiyama, M Nagao, H Itoh, S Nakanishi, ... Science 276 (5320), 1878-1881, 1997 | 174 | 1997 |
| Differentiation of mouse and human embryonic stem cells into hepatic lineages N Shiraki, K Umeda, N Sakashita, M Takeya, K Kume, S Kume Genes to cells 13 (7), 731-746, 2008 | 156 | 2008 |
| Wnt and Notch signals guide embryonic stem cell differentiation into the intestinal lineages S Ogaki, N Shiraki, K Kume, S Kume Stem Cells 31 (6), 1086-1096, 2013 | 148 | 2013 |
| Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific definitive endoderm N Shiraki, T Yoshida, K Araki, A Umezawa, Y Higuchi, H Goto, K Kume, ... Stem cells 26 (4), 874-885, 2008 | 133 | 2008 |
| Role of inositol 1, 4, 5-trisphosphate receptor in ventral signaling in Xenopus embryos S Kume, A Muto, T Inoue, K Suga, H Okano, K Mikoshiba Science 278 (5345), 1940-1943, 1997 | 129 | 1997 |
| Calcium waves along the cleavage furrows in cleavage-stage Xenopus embryos and its inhibition by heparin. A Muto, S Kume, T Inoue, H Okano, K Mikoshiba The Journal of cell biology 135 (1), 181-190, 1996 | 106 | 1996 |
| Tissue-specific demethylation in CpG-poor promoters during cellular differentiation G Nagae, T Isagawa, N Shiraki, T Fujita, S Yamamoto, S Tsutsumi, ... Human molecular genetics 20 (14), 2710-2721, 2011 | 105 | 2011 |
| Enhanced expression of PDX-1 and Ngn3 by exendin-4 during β cell regeneration in STZ-treated mice S Kodama, T Toyonaga, T Kondo, K Matsumoto, K Tsuruzoe, ... Biochemical and Biophysical Research Communications 327 (4), 1170-1178, 2005 | 105 | 2005 |
| Generation of insulin-producing β-like cells from human iPS cells in a defined and completely xeno-free culture system HM Shahjalal, N Shiraki, D Sakano, K Kikawa, S Ogaki, H Baba, K Kume, ... Journal of molecular cell biology 6 (5), 394-408, 2014 | 98 | 2014 |
| VMAT2 identified as a regulator of late-stage β-cell differentiation D Sakano, N Shiraki, K Kikawa, T Yamazoe, M Kataoka, K Umeda, ... Nature chemical biology 10 (2), 141-148, 2014 | 86 | 2014 |
| Generation of intestinal organoids derived from human pluripotent stem cells for drug testing S Yoshida, H Miwa, T Kawachi, S Kume, K Takahashi Scientific Reports 10 (1), 5989, 2020 | 85 | 2020 |
| The NMDA receptor promotes sleep in the fruit fly, Drosophila melanogaster J Tomita, T Ueno, M Mitsuyoshi, S Kume, K Kume PloS one 10 (5), e0128101, 2015 | 85 | 2015 |
| Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancreatic lineages Y Higuchi, N Shiraki, K Yamane, Z Qin, K Mochitate, K Araki, T Senokuchi, ... Journal of cell science 123 (16), 2733-2742, 2010 | 84 | 2010 |
Katsuhiko MikoshibaRIKEN BSIVerified email at brain.riken.jp
