| The epithelial-mesenchymal transition generates cells with properties of stem cells SA Mani, W Guo, MJ Liao, EN Eaton, A Ayyanan, AY Zhou, M Brooks, ... Cell 133 (4), 704-715, 2008 | 10620 | 2008 |
| Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds D Huangfu, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen, ... Nature biotechnology 26 (7), 795-797, 2008 | 2226 | 2008 |
| Integrin signalling during tumour progression W Guo, FG Giancotti Nature reviews Molecular cell biology 5 (10), 816-826, 2004 | 2041 | 2004 |
| Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 D Huangfu, K Osafune, R Maehr, W Guo, A Eijkelenboom, S Chen, ... Nature biotechnology 26 (11), 1269-1275, 2008 | 1964 | 2008 |
| Slug and Sox9 cooperatively determine the mammary stem cell state W Guo, Z Keckesova, JL Donaher, T Shibue, V Tischler, F Reinhardt, ... Cell 148 (5), 1015-1028, 2012 | 1186 | 2012 |
| Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast C Scheel, EN Eaton, SHJ Li, CL Chaffer, F Reinhardt, KJ Kah, G Bell, ... Cell 145 (6), 926-940, 2011 | 1072 | 2011 |
| β4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis W Guo, Y Pylayeva, A Pepe, T Yoshioka, WJ Muller, G Inghirami, ... Cell 126 (3), 489-502, 2006 | 616 | 2006 |
| Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression CD May, N Sphyris, KW Evans, SJ Werden, W Guo, SA Mani Breast Cancer Research 13 (1), 202, 2011 | 430 | 2011 |
| CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells P Wang, R Mokhtari, E Pedrosa, M Kirschenbaum, C Bayrak, D Zheng, ... Molecular autism 8 (1), 11, 2017 | 398 | 2017 |
| Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells WL Tam, H Lu, J Buikhuisen, BS Soh, E Lim, F Reinhardt, ZJ Wu, JA Krall, ... Cancer cell 24 (3), 347-364, 2013 | 387 | 2013 |
| Integrin-specific activation of Rac controls progression through the G1 phase of the cell cycle A Mettouchi, S Klein, W Guo, M Lopez-Lago, E Lemichez, JK Westwick, ... Molecular cell 8 (1), 115-127, 2001 | 383 | 2001 |
| Integrin β4 signaling promotes tumor angiogenesis SN Nikolopoulos, P Blaikie, T Yoshioka, W Guo, FG Giancotti Cancer cell 6 (5), 471-483, 2004 | 269 | 2004 |
| Oncogene-dependent apoptosis is mediated by caspase-9 HO Fearnhead, J Rodriguez, EE Govek, W Guo, R Kobayashi, G Hannon, ... Proceedings of the national academy of sciences 95 (23), 13664-13669, 1998 | 215 | 1998 |
| Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity MJ Liao, CC Zhang, B Zhou, DB Zimonjic, SA Mani, M Kaba, A Gifford, ... Cancer research 67 (17), 8131-8138, 2007 | 209 | 2007 |
| Targeted deletion of the integrin β4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-κB, causing defects in epidermal … SN Nikolopoulos, P Blaikie, T Yoshioka, W Guo, C Puri, C Tacchetti, ... Molecular and cellular biology 25 (14), 6090-6102, 2005 | 163 | 2005 |
| Lineage-biased stem cells maintain estrogen-receptor-positive and-negative mouse mammary luminal lineages C Wang, JR Christin, MH Oktay, W Guo Cell reports 18 (12), 2825-2835, 2017 | 124 | 2017 |
| Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination VP Sharma, B Tang, Y Wang, CL Duran, GS Karagiannis, EA Xue, ... Nature Communications 12 (1), 7300, 2021 | 118 | 2021 |
| Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem–like cell traits in breast cancer ML Luo, C Gong, CH Chen, DY Lee, H Hu, P Huang, Y Yao, W Guo, ... Cancer research 74 (13), 3603-3616, 2014 | 100 | 2014 |
| Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation SK Donnelly, R Cabrera, SPH Mao, JR Christin, B Wu, W Guo, ... Journal of Cell Biology 216 (12), 4331-4349, 2017 | 92 | 2017 |
| Mammary-stem-cell-based somatic mouse models reveal breast cancer drivers causing cell fate dysregulation Z Zhang, JR Christin, C Wang, K Ge, MH Oktay, W Guo Cell reports 16 (12), 3146-3156, 2016 | 76 | 2016 |
Robert A. WeinbergMITVerified email at wi.mit.edu
