| Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer’s Disease NS Dourado, CS Souza, MMA De Almeida, A Bispo da Silva, ... Frontiers in Aging Neuroscience 12, 119, 2020 | 139 | 2020 |
| Impact of plant-derived flavonoids on neurodegenerative diseases SL Costa, VDA Silva, C dos Santos Souza, CC Santos, I Paris, P Muñoz, ... Neurotoxicity research 30 (1), 41-52, 2016 | 134 | 2016 |
| The flavonoid rutin and its aglycone quercetin modulate the microglia inflammatory profile improving antiglioma activity AB da Silva, PLC Coelho, M das Neves Oliveira, JL Oliveira, JAO Amparo, ... Brain, behavior, and immunity 85, 170-185, 2020 | 131 | 2020 |
| Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression BL Santos, MN Oliveira, PLC Coelho, BPS Pitanga, AB da Silva, T Adelita, ... Chemico-biological interactions 242, 123-138, 2015 | 107 | 2015 |
| Alkaloids from Prosopis juliflora leaves induce glial activation, cytotoxicity and stimulate NO production. AMM Silva, AR Silva, AM Pinheiro, SRVB Freitas, VDA Silva, CS Souza, ... Toxicon 49 (5), 601-614, 2007 | 83 | 2007 |
| Role of microgliosis and NLRP3 inflammasome in Parkinson’s disease pathogenesis and therapy FM de Araujo, L Cuenca-Bermejo, E Fernandez-Villalba, SL Costa, ... Cellular and molecular neurobiology 42 (5), 1283-1300, 2022 | 68 | 2022 |
| Agathisflavone, a flavonoid derived from Poincianella pyramidalis (Tul.), enhances neuronal population and protects against glutamate excitotoxicity C dos Santos Souza, MS Grangeiro, EPL Pereira, CC Dos Santos, ... Neurotoxicology 65, 85-97, 2018 | 66 | 2018 |
| Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection associated to the modulation of astrocyte response and expression of … MS Oliveira-Junior, EP Pereira, VCM de Amorim, LTC Reis, ... International Immunopharmacology 70, 302-312, 2019 | 61 | 2019 |
| Genotoxicity and morphological changes induced by the alkaloid monocrotaline, extracted from Crotalaria retusa, in a model of glial cells JP Silva-Neto, RA Barreto, BPS Pitanga, CS Souza, VD Silva, AR Silva, ... Toxicon 55 (1), 105-117, 2010 | 60 | 2010 |
| The flavonoid rutin modulates microglial/macrophage activation to a CD150/CD206 M2 phenotype AB da Silva, PLC Coelho, JAO Amparo, MMA de Almeida Carneiro, ... Chemico-Biological Interactions 274, 89-99, 2017 | 59 | 2017 |
| Relevant Genes Linked to Virulence Are Required for Salmonella Typhimurium to Survive Intracellularly in the Social Amoeba Dictyostelium discoideum S Riquelme, M Varas, C Valenzuela, P Velozo, N Chahin, P Aguilera, ... Frontiers in microbiology 7, 1305, 2016 | 59 | 2016 |
| Combined 1-deoxynojirimycin and ibuprofen treatment decreases microglial activation, phagocytosis and dopaminergic degeneration in MPTP-treated mice TCS Costa, E Fernandez-Villalba, V Izura, AM Lucas-Ochoa, ... Journal of Neuroimmune Pharmacology 16 (2), 390-402, 2021 | 45 | 2021 |
| Aminochrome induces microglia and astrocyte activation CC Santos, FM Araújo, RS Ferreira, VB Silva, JHC Silva, MS Grangeiro, ... Toxicology In Vitro 42, 54-60, 2017 | 44 | 2017 |
| Phytoestrogen agathisflavone ameliorates neuroinflammation-induced by LPS and IL-1β and protects neurons in cocultures of glia/neurons MMA de Almeida, CS Souza, NS Dourado, AB da Silva, RS Ferreira, ... Biomolecules 10 (4), 562, 2020 | 42 | 2020 |
| Juliprosopine and Juliprosine from Prosopis juliflora Leaves Induce Mitochondrial Damage and Cytoplasmic Vacuolation on Cocultured Glial Cells and Neurons VDA Silva, BPS Pitanga, RP Nascimento, CS Souza, PLC Coelho, ... Chemical Research in Toxicology 26 (12), 1810-1820, 2013 | 42 | 2013 |
| Amburana cearensis: Pharmacological and Neuroprotective Effects of Its Compounds JHCE Silva, RS Ferreira, EP Pereira, S Braga-de-Souza, MMA Almeida, ... Molecules 25 (15), 3394, 2020 | 40 | 2020 |
| Neuroimmunomodulatory properties of flavonoids and derivates: A potential action as adjuvants for the treatment of glioblastoma RP do Nascimento, BL Dos Santos, JAO Amparo, JRP Soares, ... Pharmaceutics 14 (1), 116, 2022 | 39 | 2022 |
| The flavonoid apigenin from Croton betulaster Mull inhibits proliferation, induces differentiation and regulates the inflammatory profile of glioma cells PLC Coelho, MN Oliveira, AB da Silva, BPS Pitanga, VDA Silva, GP Faria, ... Anti-Cancer Drugs 27 (10), 960-969, 2016 | 39 | 2016 |
| Identification of bioactive metabolites from corn silk extracts by a combination of metabolite profiling, univariate statistical analysis and chemometrics NRS da Hora, LF Santana, VDA da Silva, SL Costa, L Zambotti-Villela, ... Food Chemistry 365, 130479, 2021 | 38 | 2021 |
| Combination of a multiplatform metabolite profiling approach and chemometrics as a powerful strategy to identify bioactive metabolites in Lepidium meyenii (Peruvian maca) FV Carvalho, LF Santana, VDA da Silva, SL Costa, L Zambotti-Villelae, ... Food Chemistry 364, 130453, 2021 | 35 | 2021 |