| Handbook of biologically active peptides A Kastin Academic press, 2013 | 962 | 2013 |
| Animal models in the pathophysiology of cystic fibrosis A Semaniakou, RP Croll, V Chappe Frontiers in pharmacology 9, 1475, 2019 | 142 | 2019 |
| Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA V Chappe, DA Hinkson, T Zhu, XB Chang, JR Riordan, JW Hanrahan The Journal of physiology 548 (1), 39-52, 2003 | 142 | 2003 |
| The role of ghrelin in the regulation of glucose homeostasis BN Alamri, K Shin, V Chappe, Y Anini Hormone molecular biology and clinical investigation 26 (1), 3-11, 2016 | 136 | 2016 |
| Development of substituted Benzo [c] quinolizinium compounds as novel activators of the cystic fibrosis chloride channel F Becq, Y Mettey, MA Gray, LJV Galietta, RL Dormer, M Merten, T Métayé, ... Journal of Biological Chemistry 274 (39), 27415-27425, 1999 | 134 | 1999 |
| ClC channels and transporters: structure, physiological functions, and implications in human chloride channelopathies DR Poroca, RM Pelis, VM Chappe Frontiers in pharmacology 8, 151, 2017 | 128 | 2017 |
| Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator V Chappe, DA Hinkson, LD Howell, A Evagelidis, J Liao, XB Chang, ... Proceedings of the National Academy of Sciences 101 (1), 390-395, 2004 | 123 | 2004 |
| Phosphorylation of CFTR by PKA promotes binding of the regulatory domain V Chappe, T Irvine, J Liao, A Evagelidis, JW Hanrahan The EMBO journal 24 (15), 2730-2740, 2005 | 121 | 2005 |
| Structural basis for specificity and potency of xanthine derivatives as activators of the CFTR chloride channel V Chappe, Y Mettey, JM Vierfond, JW Hanrahan, M Gola, B Verrier, ... British journal of pharmacology 123 (4), 683-693, 1998 | 71 | 1998 |
| PKC phosphorylation modulates PKA-dependent binding of the R domain to other domains of CFTR G Seavilleklein, N Amer, A Evagelidis, F Chappe, T Irvine, JW Hanrahan, ... American Journal of Physiology-Cell Physiology 295 (5), C1366-C1375, 2008 | 52 | 2008 |
| VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1-and PKCε-dependent manner W Alshafie, FG Chappe, M Li, Y Anini, VM Chappe American Journal of Physiology-Cell Physiology 307 (1), C107-C119, 2014 | 41 | 2014 |
| Pharmacological and signaling properties of endogenous P2Y1 receptors in cystic fibrosis transmembrane conductance regulator-expressing Chinese hamster ovary cells B Marcet, V Chappe, P Delmas, B Verrier The Journal of pharmacology and experimental therapeutics 309 (2), 533-539, 2004 | 34 | 2004 |
| Cystic fibrosis transmembrane conductance regulator (CFTR) confers glibenclamide sensitivity to outwardly rectifying chloride channel (ORCC) in Hi-5 insect cells M Julien, B Verrier, M Cerutti, V Chappe, M Gola, G Devauchelle, F Becq The Journal of membrane biology 168 (3), 229-239, 1999 | 28 | 1999 |
| Vasoactive intestinal peptide increases cystic fibrosis transmembrane conductance regulator levels in the apical membrane of Calu-3 cells through a protein kinase C-dependent … F Chappe, ME Loewen, JW Hanrahan, V Chappe The Journal of pharmacology and experimental therapeutics 327 (1), 226-238, 2008 | 25 | 2008 |
| Cystic fibrosis transmembrane conductance regulator dysfunction in VIP knockout mice NG Alcolado, DJ Conrad, D Poroca, M Li, W Alshafie, FG Chappe, ... American Journal of Physiology-Cell Physiology 307 (2), C195-C207, 2014 | 24 | 2014 |
| Rescue of functional F508del cystic fibrosis transmembrane conductance regulator by vasoactive intestinal peptide in the human nasal epithelial cell line JME/CF15 S Rafferty, N Alcolado, C Norez, F Chappe, S Pelzer, F Becq, V Chappe The Journal of pharmacology and experimental therapeutics 331 (1), 2-13, 2009 | 19 | 2009 |
| VIP-dependent increase in F508del-CFTR membrane localization is mediated by PKCε N Alcolado, DJ Conrad, S Rafferty, FG Chappe, VM Chappe American Journal of Physiology-Cell Physiology 301 (1), C53-C65, 2011 | 18 | 2011 |
| Iron chelation as novel treatment for lung inflammation in cystic fibrosis M Aali, A Caldwell, K House, J Zhou, V Chappe, C Lehmann Medical Hypotheses 104, 86-88, 2017 | 16 | 2017 |
| Negative regulation of CFTR activity by extracellular ATP involves P2Y2 receptors in CFTR-expressing CHO cells B Marcet, V Chappe, P Delmas, M Gola, B Verrier The Journal of membrane biology 194 (1), 21-32, 2003 | 14 | 2003 |
| Disrupted local innervation results in less VIP expression in CF mice tissues A Semaniakou, S Brothers, G Gould, M Zahiremani, J Paton, F Chappe, ... Journal of Cystic Fibrosis 20 (1), 154-164, 2021 | 12 | 2021 |
John W. HanrahanMcGill UniversityVerified email at mcgill.ca
