| Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128· 9 million … L Abarca-Gómez, ZA Abdeen, ZA Hamid, NM Abu-Rmeileh, ... The lancet 390 (10113), 2627-2642, 2017 | 9930 | 2017 |
| Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19· 2 million participants NCD Risk Factor Collaboration Lancet (London, England) 387 (10026), 1377, 2016 | 6347 | 2016 |
| Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015 | 5408 | 2015 |
| Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 5073 | 2013 |
| C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease J Danesh, JG Wheeler, GM Hirschfield, S Eda, G Eiriksdottir, A Rumley, ... New England journal of medicine 350 (14), 1387-1397, 2004 | 4347 | 2004 |
| Biological, clinical and population relevance of 95 loci for blood lipids TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ... Nature 466 (7307), 707-713, 2010 | 4299 | 2010 |
| Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 … B Zhou, RM Carrillo-Larco, G Danaei, LM Riley, CJ Paciorek, GA Stevens, ... The lancet 398 (10304), 957-980, 2021 | 4153 | 2021 |
| New creatinine-and cystatin C–based equations to estimate GFR without race LA Inker, ND Eneanya, J Coresh, H Tighiouart, D Wang, Y Sang, ... New England Journal of Medicine 385 (19), 1737-1749, 2021 | 4001 | 2021 |
| Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3799 | 2010 |
| Major lipids, apolipoproteins, and risk of vascular disease R Assessment Jama 302 (18), 1993-2000, 2009 | 3368 | 2009 |
| Discovery and refinement of loci associated with lipid levels Nature genetics 45 (11), 1274-1283, 2013 | 3316 | 2013 |
| Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19· 1 million participants B Zhou, J Bentham, M Di Cesare, H Bixby, G Danaei, MJ Cowan, ... The Lancet 389 (10064), 37-55, 2017 | 3248 | 2017 |
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 3147 | 2019 |
| C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis Emerging Risk Factors Collaboration The Lancet 375 (9709), 132-140, 2010 | 3146 | 2010 |
| Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes SFA Grant, G Thorleifsson, I Reynisdottir, R Benediktsson, A Manolescu, ... Nature genetics 38 (3), 320-323, 2006 | 3011 | 2006 |
| Diabetes mellitus, fasting glucose, and risk of cause-specific death Emerging Risk Factors Collaboration New England Journal of Medicine 364 (9), 829-841, 2011 | 2958 | 2011 |
| A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease Nature genetics 47 (10), 1121-1130, 2015 | 2839 | 2015 |
| Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ... Nature 478 (7367), 103-109, 2011 | 2458 | 2011 |
| Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2431 | 2010 |
| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 2423 | 2022 |