| High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ... Science translational medicine 13 (596), eabf8654, 2021 | 301* | 2021 |
| High-throughput functional genetic and compound screens identify targets for senescence induction in cancer L Wang, RL de Oliveira, C Wang, JMF Neto, S Mainardi, B Evers, ... Cell reports 21 (3), 773-783, 2017 | 258 | 2017 |
| Macrophage subsets in atherosclerosis as defined by single‐cell technologies L Willemsen, MPJ de Winther The Journal of pathology 250 (5), 705-714, 2020 | 256 | 2020 |
| Trained immunity-promoting nanobiologic therapy suppresses tumor growth and potentiates checkpoint inhibition B Priem, MMT van Leent, AJP Teunissen, AM Sofias, VP Mourits, ... Cell 183 (3), 786-801. e19, 2020 | 190 | 2020 |
| Impact of cholesterol on proinflammatory monocyte production by the bone marrow LCA Stiekema, L Willemsen, Y Kaiser, KHM Prange, NJ Wareham, ... European Heart Journal 42 (42), 4309-4320, 2021 | 75 | 2021 |
| Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages’ transition into a pro-inflammatory state LA Bosmans, CM van Tiel, SABM Aarts, L Willemsen, J Baardman, ... Cardiovascular research 119 (5), 1146-1160, 2023 | 56 | 2023 |
| Targeting epigenetics as atherosclerosis treatment: an updated view AE Neele, L Willemsen, HJ Chen, KE Dzobo, MPJ de Winther Current Opinion in Lipidology 31 (6), 324-330, 2020 | 32 | 2020 |
| Hematopoietic somatic mosaicism is associated with an increased risk of postoperative atrial fibrillation S Ninni, D Dombrowicz, T Kuznetsova, R Vicario, V Gao, O Molendi-Coste, ... Journal of the American College of Cardiology 81 (13), 1263-1278, 2023 | 31 | 2023 |
| DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability L Willemsen, KHM Prange, AE Neele, CPAA van Roomen, M Gijbels, ... Cell Reports 41 (8), 111703, 2022 | 31 | 2022 |
| Antigen-specificity measurements are the key to understanding T cell responses R Tippalagama, LY Chihab, K Kearns, S Lewis, S Panda, L Willemsen, ... Frontiers in Immunology 14, 1127470, 2023 | 27 | 2023 |
| Monocyte and macrophage lipid accumulation results in down-regulated type-I interferon responses L Willemsen, HJ Chen, CPAA van Roomen, GR Griffith, R Siebeler, ... Frontiers in Cardiovascular Medicine 9, 169, 2022 | 24 | 2022 |
| Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss L Willemsen, AE Neele, S Van Der Velden, KHM Prange, M Den Toom, ... BMJ open diabetes research & care 7 (1), 2019 | 22 | 2019 |
| Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques KJ Harber, AE Neele, CPAA van Roomen, MJJ Gijbels, L Beckers, ... Redox biology 70, 103054, 2024 | 18 | 2024 |
| The human milk oligosaccharide 3′ sialyllactose reduces low-grade inflammation and atherosclerosis development in mice AR Pessentheiner, NJ Spann, CA Autran, TG Oh, KV Grunddal, ... JCI insight 9 (21), e181329, 2024 | 12 | 2024 |
| Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction ME Reiche, M Den Toom, L Willemsen, B Van Os, MJJ Gijbels, N Gerdes, ... BMJ Open Diabetes Research & Care 7 (1), 2019 | 12 | 2019 |
| Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop L Willemsen, J Lee, P Shinde, F Soldevila, M Aoki, S Orfield, M Kojima, ... Nature Communications 16 (1), 3132, 2025 | 10 | 2025 |
| A multi-omics systems vaccinology resource to develop and test computational models of immunity P Shinde, F Soldevila, J Reyna, M Aoki, M Rasmussen, L Willemsen, ... Cell Reports Methods 4 (3), 2024 | 8* | 2024 |
| Putting computational models of immunity to the test—An invited challenge to predict B.pertussis vaccination responses P Shinde, L Willemsen, M Anderson, M Aoki, S Basu, JG Burel, P Cheng, ... PLoS computational biology 21 (3), e1012927, 2025 | 3* | 2025 |
| Is the vaccination-induced B cell receptor repertoire predictable? E Richardson, L Willemsen, P Shinde, M Nielsen, B Peters ImmunoInformatics, 100057, 2025 | 1 | 2025 |
| Exploring Pertussis Vaccination Through Systems Vaccinology J Hsiao, P Shinde, L Willemsen, M Kojima, J Reyna, B Peters, BJ Grant | 1 | 2025 |
