| Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing S Sadegh, J Matschinske, DB Blumenthal, G Galindez, T Kacprowski, ... Nature communications 11 (1), 3518, 2020 | 200 | 2020 |
| Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research F Hufsky, K Lamkiewicz, A Almeida, A Aouacheria, C Arighi, A Bateman, ... Briefings in bioinformatics 22 (2), 642-663, 2021 | 172 | 2021 |
| Network medicine for disease module identification and drug repurposing with the NeDRex platform S Sadegh, J Skelton, E Anastasi, J Bernett, DB Blumenthal, G Galindez, ... Nature communications 12 (1), 6848, 2021 | 143 | 2021 |
| Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies G Galindez, J Matschinske, TD Rose, S Sadegh, M Salgado-Albarrán, ... Nature Computational Science 1 (1), 33-41, 2021 | 132 | 2021 |
| Network-based approaches for modeling disease regulation and progression G Galindez, S Sadegh, J Baumbach, T Kacprowski, M List Computational and structural biotechnology journal 21, 780-795, 2023 | 56 | 2023 |
| NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype MH Elbatreek, S Sadegh, E Anastasi, E Guney, C Nogales, T Kacprowski, ... PLoS Biology 18 (11), e3000885, 2020 | 56 | 2020 |
| Robust disease module mining via enumeration of diverse prize-collecting Steiner trees J Bernett, D Krupke, S Sadegh, J Baumbach, SP Fekete, T Kacprowski, ... Bioinformatics 38 (6), 1600-1606, 2022 | 33 | 2022 |
| Drugst. One—a plug-and-play solution for online systems medicine and network-based drug repurposing A Maier, M Hartung, M Abovsky, K Adamowicz, GD Bader, S Baier, ... Nucleic Acids Research 52 (W1), W481-W488, 2024 | 31 | 2024 |
| Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond S Sadegh, J Skelton, E Anastasi, A Maier, K Adamowicz, A Möller, ... Nature Communications 14 (1), 1662, 2023 | 17 | 2023 |
| Individuating possibly repurposable drugs and drug targets for COVID-19 treatment through hypothesis-driven systems medicine using CoVex J Matschinske, M Salgado-Albarrán, S Sadegh, D Bongiovanni, ... Assay and drug development technologies 18 (8), 348-355, 2020 | 13 | 2020 |
| Network medicine-based unbiased disease modules for drug and diagnostic target identification in ROSopathies C Nogales, AGB Grønning, S Sadegh, J Baumbach, HHHW Schmidt Reactive Oxygen Species: Network Pharmacology and Therapeutic Applications …, 2020 | 10 | 2020 |
| Drugst A Maier, M Hartung, M Abovsky, K Adamowicz, GD Bader, S Baier, ... One–a plug-and-play solution for online systems medicine and network-based …, 2023 | 7 | 2023 |
| Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing. Nat Commun 11: 3518 S Sadegh, J Matschinske, DB Blumenthal, G Galindez, T Kacprowski, ... | 7 | 2020 |
| NeDRex-an integrative and interactive network medicine platform for drug repurposing S Sadegh, J Skelton, E Anastasi, DB Blumenthal, A Maier, G Galindez, ... RExPO22, 2022 | 4 | 2022 |
| Synergistic Network Pharmacology: Preclinical Validation and Clinical Safety in Acute Ischemic Stroke AI Casas, C Nogales, RD Szepanowski, MH Elbatreek, E Anastasi, ... Journal of the American Heart Association 14 (10), e039098, 2025 | 3 | 2025 |
| Nedrex-web: an interactive web tool for drug repurposing by exploring heterogeneous molecular networks A Maier, M Rafiei, E Anastasi, O Zolotareva, J Skelton, ML Elkjaer, ... 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2024 | 3 | 2024 |
| Randomization strategies affect motif significance analysis in TF-miRNA-gene regulatory networks S Sadegh, M Nazarieh, C Spaniol, V Helms Journal of Integrative Bioinformatics 14 (2), 20170017, 2017 | 2 | 2017 |
| A Sensitive and Transparent Method for Tumor-Informed Detection of Circulating Tumor DNA in Ovarian Cancer Using Whole-Genome Sequencing CF Thusgaard, S Sadegh, KM Jochumsen, TA Kruse, M Thomassen International Journal of Molecular Sciences 25 (24), 13349, 2024 | 1 | 2024 |
| A plug-and-play solution to bring network exploration and drug repurposing to biomedical web platforms M Hartung, A Maier, S Sadegh, J Matschinske, M List, OI Zolotareva, ... RExPO22, 2022 | 1 | 2022 |
| Network pharmacology drug repurposing strategy for neurovascular diseases AI Casas, C Nogales, MH Elbatreek, S Sadegh, E Anastasi, J Skelton, ... RExPO22, 2022 | 1 | 2022 |
Jan BaumbachInstitute for Computational Systems Biology, University of HamburgVerified email at cosy.bio
