| Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs M de Lourdes G. Ferreira, LCS Pinheiro, OA Santos-Filho, MDS Peçanha, ... Medicinal Chemistry Research 23 (3), 1501-1511, 2014 | 160 | 2014 |
| Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection LC Manjolin, MBG dos Reis, C do Carmo Maquiaveli, OA Santos-Filho, ... Food chemistry 141 (3), 2253-2262, 2013 | 125 | 2013 |
| Inhibition of Leishmania (Leishmania) amazonensis and Rat Arginases by Green Tea EGCG, (+)-Catechin and (−)-Epicatechin: A Comparative Structural Analysis … MBG dos Reis, LC Manjolin, CC Maquiaveli, OA Santos-Filho, ... PLoS One 8 (11), e78387, 2013 | 103 | 2013 |
| Modelagem de proteínas por homologia OA Santos Filho, RB Alencastro Química Nova 26, 253-259, 2003 | 85 | 2003 |
| Mapping the Protein Interaction Network in Methicillin-Resistant Staphylococcus aureus A Cherkasov, M Hsing, R Zoraghi, LJ Foster, RH See, N Stoynov, J Jiang, ... Journal of proteome research 10 (3), 1139-1150, 2011 | 83 | 2011 |
| Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes N Boechat, LCS Pinheiro, OA Santos-Filho, IC Silva Molecules 16 (9), 8083-8097, 2011 | 81 | 2011 |
| Rational design of new antituberculosis agents: receptor-independent four-dimensional quantitative structure− activity relationship analysis of a set of isoniazid derivatives KFM Pasqualoto, EI Ferreira, OA Santos-Filho, AJ Hopfinger Journal of medicinal chemistry 47 (15), 3755-3764, 2004 | 79 | 2004 |
| Type 2 antifolates in the chemotherapy of falciparum malaria RT Delfino, OA Santos-Filho, JD Figueroa-Villar Journal of the Brazilian Chemical Society 13, 727-741, 2002 | 79 | 2002 |
| New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodiumfalciparum Agents N Boechat, LCS Pinheiro, TS Silva, ACC Aguiar, AS Carvalho, MM Bastos, ... Molecules 17 (7), 8285-8302, 2012 | 75 | 2012 |
| Molecular modeling of wild-type and antifolate resistant mutant Plasmodium falciparum DHFR RT Delfino, OA Santos-Filho, JD Figueroa-Villar Biophysical chemistry 98 (3), 287-300, 2002 | 66 | 2002 |
| A search for sources of drug resistance by the 4D-QSAR analysis of a set of antimalarial dihydrofolate reductase inhibitors OA Santos-Filho, AJ Hopfinger Journal of computer-aided molecular design 15 (1), 1-12, 2001 | 57 | 2001 |
| The receptor-dependent QSAR paradigm: an overview of the current state of the art OA Santos-Filho, AJ Hopfinger, A Cherkasov, RB de Alencastro Medicinal Chemistry 5 (4), 359-366, 2009 | 50 | 2009 |
| Aureonitol, a fungi-derived tetrahydrofuran, inhibits influenza replication by targeting its surface glycoprotein hemagglutinin CQ Sacramento, A Marttorelli, N Fintelman-Rodrigues, CS de Freitas, ... PLoS One 10 (10), e0139236, 2015 | 47 | 2015 |
| An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin A Cherkasov, F Ban, O Santos-Filho, N Thorsteinson, M Fallahi, ... Journal of medicinal chemistry 51 (7), 2047-2056, 2008 | 47 | 2008 |
| Free energy force field (FEFF) 3D-QSAR analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors OA Santos-Filho, RK Mishra, AJ Hopfinger Journal of Computer-Aided Molecular Design 15 (9), 787-810, 2001 | 42 | 2001 |
| Homology modeling of wild type and pyrimethamine/cycloguanil-cross resistant mutant type Plasmodium falciparum dihydrofolate reductase. A model for antimalarial chemotherapy … OA Santos-Filho, RB de Alencastro, JD Figueroa-Villar Biophysical Chemistry 91 (3), 305-317, 2001 | 38 | 2001 |
| Geissoschizoline, a promising alkaloid for Alzheimer’s disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking JA Lima, TWR Costa, ACC da Fonseca, RF do Amaral, ... Bioorganic Chemistry 104, 104215, 2020 | 33 | 2020 |
| Structure-based QSAR analysis of a set of 4-hydroxy-5, 6-dihydropyrones as inhibitors of HIV-1 protease: an application of the receptor-dependent (RD) 4D-QSAR formalism OA Santos-Filho, AJ Hopfinger Journal of chemical information and modeling 46 (1), 345-354, 2006 | 33 | 2006 |
| In silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin N Thorsteinson, F Ban, O Santos-Filho, SMH Tabaei, S Miguel-Queralt, ... Toxicology and applied pharmacology 234 (1), 47-57, 2009 | 32 | 2009 |
| The 4D‐QSAR Paradigm: Application to a Novel Set of Non‐peptidic HIV Protease Inhibitors OA Santos‐Filho, AJ Hopfinger Quantitative Structure‐Activity Relationships 21 (4), 369-381, 2002 | 30 | 2002 |
