| The relationship between the chemistry and biological activity of the bisphosphonates FH Ebetino, AML Hogan, S Sun, MK Tsoumpra, X Duan, JT Triffitt, ... Bone 49 (1), 20-33, 2011 | 505 | 2011 |
| Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption MM McDonald, WH Khoo, PY Ng, Y Xiao, J Zamerli, P Thatcher, W Kyaw, ... Cell 184 (5), 1330-1347. e13, 2021 | 469 | 2021 |
| Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo AJ Roelofs, FP Coxon, FH Ebetino, MW Lundy, ZJ Henneman, ... Journal of Bone and Mineral Research 25 (3), 606-616, 2010 | 199 | 2010 |
| Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer S Junankar, G Shay, J Jurczyluk, N Ali, J Down, N Pocock, A Parker, ... Cancer discovery 5 (1), 35-42, 2015 | 168 | 2015 |
| Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: role in osteoclast-mediated NK cell activation HC Tseng, K Kanayama, K Kaur, SH Park, S Park, A Kozlowska, S Sun, ... Oncotarget 6 (24), 20002, 2015 | 127 | 2015 |
| Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo AJ Roelofs, CA Stewart, S Sun, KM Błażewska, BA Kashemirov, ... Journal of Bone and Mineral Research 27 (4), 835-847, 2012 | 123 | 2012 |
| Design, synthesis, and antimicrobial evaluation of a novel bone-targeting bisphosphonate-ciprofloxacin conjugate for the treatment of osteomyelitis biofilms PP Sedghizadeh, S Sun, AF Junka, E Richard, K Sadrerafi, S Mahabady, ... Journal of medicinal chemistry 60 (6), 2326-2343, 2017 | 111 | 2017 |
| Bisphosphonates: The role of chemistry in understanding their biological actions and structure-activity relationships, and new directions for their therapeutic use FH Ebetino, S Sun, P Cherian, S Roshandel, JD Neighbors, E Hu, ... Bone 156, 116289, 2022 | 91 | 2022 |
| Equilibrium-dependent bisphosphonate interaction with crystalline bone mineral explains anti-resorptive pharmacokinetics and prevalence of osteonecrosis of the jaw in rats A Hokugo, S Sun, S Park, CE McKenna, I Nishimura Bone 53 (1), 59-68, 2013 | 59 | 2013 |
| Farnesyl pyrophosphate synthase modulators: a patent review (2006–2010) S Sun, CE McKenna Expert opinion on therapeutic patents 21 (9), 1433-1451, 2011 | 57 | 2011 |
| Jaw bone marrow-derived osteoclast precursors internalize more bisphosphonate than long-bone marrow precursors JAF Vermeer, IDC Jansen, M Marthi, FP Coxon, CE McKenna, S Sun, ... Bone 57 (1), 242-251, 2013 | 55 | 2013 |
| Bisphosphonate uptake in areas of tooth extraction or periapical disease S Cheong, S Sun, B Kang, O Bezouglaia, D Elashoff, CE McKenna, ... Journal of Oral and Maxillofacial Surgery 72 (12), 2461-2468, 2014 | 53 | 2014 |
| Fluorescent bisphosphonate and carboxyphosphonate probes: a versatile imaging toolkit for applications in bone biology and biomedicine S Sun, KM Błażewska, AP Kadina, BA Kashemirov, X Duan, JT Triffitt, ... Bioconjugate chemistry 27 (2), 329-340, 2016 | 51 | 2016 |
| Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits J Turek, FH Ebetino, MW Lundy, S Sun, BA Kashemirov, CE McKenna, ... Calcified tissue international 90 (3), 202-210, 2012 | 46 | 2012 |
| Bisphosphonates for delivering drugs to bone S Sun, J Tao, PP Sedghizadeh, P Cherian, AF Junka, E Sodagar, L Xing, ... British journal of pharmacology 178 (9), 2008-2025, 2021 | 42 | 2021 |
| Rescue bisphosphonate treatment of alveolar bone improves extraction socket healing and reduces osteonecrosis in zoledronate-treated mice A Hokugo, K Kanayama, S Sun, K Morinaga, Y Sun, QQ Wu, H Sasaki, ... Bone 123, 115-128, 2019 | 42 | 2019 |
| N-phosphorylation of amino acids by trimetaphosphate in aqueous solution—learning from prebiotic synthesis F Ni, S Sun, C Huang, Y Zhao Green Chemistry 11 (4), 569-573, 2009 | 39 | 2009 |
| Development of oral osteomucosal tissue constructs in vitro and localization of fluorescently-labeled bisphosphonates to hard and soft tissue S Bae, S Sun, T Aghaloo, JE Oh, CE McKenna, MK Kang, KH Shin, S Tetradis, NH ... International journal of molecular medicine 34, 559-563, 2014 | 36 | 2014 |
| Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene … H Okawa, T Kondo, A Hokugo, P Cherian, JJ Campagna, NA Lentini, ... Elife 11, e76207, 2022 | 31 | 2022 |
| Bisphosphonate quinolone conjugates and uses thereof FH Ebetino, S Sun, MW Lundy, CE McKenna, E Richard, ... US Patent 10,865,220, 2020 | 31 | 2020 |
