| Enantioselective synthesis of a highly potent selective serotonin reuptake inhibitor. An application of imidazolidinone catalysis to the alkylation of indoles with an α, β … HD King, Z Meng, D Denhart, R Mattson, R Kimura, D Wu, Q Gao, ... Organic Letters 7 (16), 3437-3440, 2005 | 162 | 2005 |
| Discovery of AZD9833, a potent and orally bioavailable selective estrogen receptor degrader and antagonist JS Scott, TA Moss, A Balazs, B Barlaam, J Breed, RJ Carbajo, ... Journal of medicinal chemistry 63 (23), 14530-14559, 2020 | 119 | 2020 |
| Discovery of AZD4573, a potent and selective inhibitor of CDK9 that enables short duration of target engagement for the treatment of hematological malignancies B Barlaam, R Casella, J Cidado, C Cook, C De Savi, A Dishington, ... Journal of medicinal chemistry 63 (24), 15564-15590, 2020 | 108 | 2020 |
| Hydraulics play an important role in causing low growth rate and dieback of aging Pinus sylvestris var. mongolica trees in plantations of Northeast China YY Liu, AY Wang, YN An, PY Lian, DD Wu, JJ Zhu, FC Meinzer, GY Hao Plant, Cell & Environment 41 (7), 1500-1511, 2018 | 102 | 2018 |
| Regioselective synthesis of 3-(heteroaryl)-iminothiazolidin-4-ones DRS Laurent, Q Gao, D Wu, MH Serrano-Wu Tetrahedron letters 45 (9), 1907-1910, 2004 | 78 | 2004 |
| Discovery of a potent respiratory syncytial virus RNA polymerase inhibitor H Xiong, M Foulk, L Aschenbrenner, J Fan, CL Tiong-Yip, KD Johnson, ... Bioorganic & medicinal chemistry letters 23 (24), 6789-6793, 2013 | 73 | 2013 |
| Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse … JS Scott, SL Degorce, R Anjum, J Culshaw, RDM Davies, NL Davies, ... Journal of medicinal chemistry 60 (24), 10071-10091, 2017 | 68 | 2017 |
| Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 12. Structure–Activity Relationships Associated with 4-Fluoro-6-azaindole Derivatives Leading to the … A Regueiro-Ren, QM Xue, JJ Swidorski, YF Gong, M Mathew, DD Parker, ... Journal of medicinal chemistry 56 (4), 1656-1669, 2013 | 64 | 2013 |
| Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives T Wang, JF Kadow, Z Zhang, Z Yin, Q Gao, D Wu, DDG Parker, Z Yang, ... Bioorganic & medicinal chemistry letters 19 (17), 5140-5145, 2009 | 64 | 2009 |
| (S)-N-[1-(4-Cyclopropylmethyl-3, 4-dihydro-2H-benzo, oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced … YJ Wu, CG Boissard, J Chen, W Fitzpatrick, Q Gao, VK Gribkoff, ... Bioorganic & medicinal chemistry letters 14 (8), 1991-1995, 2004 | 38 | 2004 |
| Optimization of M4 positive allosteric modulators (PAMs): the discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology BJ Melancon, MR Wood, MJ Noetzel, KD Nance, EM Engelberg, C Han, ... Bioorganic & medicinal chemistry letters 27 (11), 2296-2301, 2017 | 35 | 2017 |
| Dinuclear Molybdenum and Tungsten Complexes with Metal−Metal Triple Bonds Supported by p-tert-Butylcalix[4]arene Ligands MH Chisholm, K Folting, WE Streib, DD Wu Inorganic Chemistry 38 (23), 5219-5229, 1999 | 35 | 1999 |
| Identification of a Potent and Selective 5-HT6 Antagonist: One-Step Synthesis of (E)-3-(Benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2-a]pyrimidin- 4 … YJ Wu, H He, S Hu, Y Huang, PM Scola, K Grant-Young, RL Bertekap, ... Journal of medicinal chemistry 46 (23), 4834-4837, 2003 | 32 | 2003 |
| Syntheses, structures and spectroscopic properties of [Ag (dppm)(O2CCH2Ph)] 2 and [Ag2 (dppm) 3](NO3) 2· 3H2O M Hong, D Wu, H Liu, TCW Mak, Z Zhou, D Wu, S Li Polyhedron 16 (11), 1957-1962, 1997 | 32 | 1997 |
| Lanthanide coordination polymers with dicarboxylate-like ligands: crystal structures of polymeric neodymium (III) and erbium (III) complexes with flexible double betaines PR Wei, DD Wu, ZY Zhou, SL Li, TCW Mak Polyhedron 16 (5), 749-763, 1997 | 32 | 1997 |
| (R)-2-(4-Phenylbutyl) dihydrobenzofuran derivatives as melatoninergic agents LQ Sun, K Takaki, J Chen, S Bertenshaw, L Iben, CD Mahle, E Ryan, ... Bioorganic & medicinal chemistry letters 15 (5), 1345-1349, 2005 | 30 | 2005 |
| Building two-dimensional silver (I) co-ordination polymers with dicarboxylate-like ligands: Synthesis and crystal structures of polymeric complexes of silver nitrate and … CW Thomas Journal of the Chemical Society, Dalton Transactions, 2671-2678, 1995 | 29 | 1995 |
| Greater hydraulic safety contributes to higher growth resilience to drought across seven pine species in a semi-arid environment CY Duan, MY Li, LD Fang, Y Cao, DD Wu, H Liu, Q Ye, GY Hao Tree Physiology 42 (4), 727-739, 2022 | 28 | 2022 |
| Generation of coordination networks with dicarboxylate-like ligands: Synthesis and crystal structures of polymeric complexes of gadolinium (III) perchlorate with flexible … PR Wei, DD Wu, ZY Zhou, TCW Mak Polyhedron 17 (4), 497-505, 1998 | 28 | 1998 |
| Synthesis and KCNQ2 opener activity of N-(1-benzo [1, 3] dioxol-5-yl-ethyl, N-[1-(2, 3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2, 3-dihydro-1H-indol-5-yl)-ethyl acrylamides YJ Wu, LQ Sun, H He, J Chen, JE Starrett Jr, P Dextraze, JP Daris, ... Bioorganic & medicinal chemistry letters 14 (17), 4533-4537, 2004 | 26 | 2004 |
