| Mitochondrial dysfunction prevents repolarization of inflammatory macrophages J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ... Cell reports 17 (3), 684-696, 2016 | 986 | 2016 |
| PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia SJ Bernelot Moens, AE Neele, J Kroon, FM Van Der Valk, ... European heart journal 38 (20), 1584-1593, 2017 | 219 | 2017 |
| Analysis of genetically diverse macrophages reveals local and domain-wide mechanisms that control transcription factor binding and function VM Link, SH Duttke, HB Chun, IR Holtman, E Westin, MA Hoeksema, ... Cell 173 (7), 1796-1809. e17, 2018 | 210 | 2018 |
| Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis TTP Seijkens, CM van Tiel, PJH Kusters, D Atzler, O Soehnlein, ... Journal of the American College of Cardiology 71 (5), 527-542, 2018 | 206 | 2018 |
| Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions MA Hoeksema, MJJ Gijbels, J Van den Bossche, S van der Velden, ... EMBO molecular medicine 6 (9), 1124-1132, 2014 | 200 | 2014 |
| Epigenetic regulation of monocyte and macrophage function MA Hoeksema, MPJ de Winther Antioxidants & redox signaling 25 (14), 758-774, 2016 | 148 | 2016 |
| High-density lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-κB/STAT1-IRF1 signaling EPC van Der Vorst, K Theodorou, Y Wu, MA Hoeksema, P Goossens, ... Cell metabolism 25 (1), 197-207, 2017 | 142 | 2017 |
| Hypercholesterolemia‐induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis T Seijkens, MA Hoeksema, L Beckers, E Smeets, S Meiler, J Levels, ... The FASEB Journal 28 (5), 2202-2213, 2014 | 139 | 2014 |
| Macrophage polarization: the epigenetic point of view J Van den Bossche, AE Neele, MA Hoeksema, MPJ De Winther Current opinion in lipidology 25 (5), 367-373, 2014 | 114 | 2014 |
| Molecular pathways regulating macrophage polarization: implications for atherosclerosis MA Hoeksema, JL Stöger, MPJ de Winther Current atherosclerosis reports 14 (3), 254-263, 2012 | 104 | 2012 |
| IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment MA Hoeksema, BP Scicluna, M Boshuizen, S Van Der Velden, AE Neele, ... The Journal of Immunology 194 (8), 3909-3916, 2015 | 95 | 2015 |
| Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis AE Neele, J Van den Bossche, MA Hoeksema, MPJ De Winther European journal of pharmacology 763, 79-89, 2015 | 86 | 2015 |
| Inhibiting epigenetic enzymes to improve atherogenic macrophage functions J Van den Bossche, AE Neele, MA Hoeksema, F De Heij, MCS Boshuizen, ... Biochemical and biophysical research communications 455 (3-4), 396-402, 2014 | 86 | 2014 |
| The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands Z Czimmerer, L Halasz, B Daniel, Z Varga, K Bene, A Domokos, ... Immunity 55 (11), 2006-2026. e6, 2022 | 73 | 2022 |
| The regulatory landscape of macrophage interferon signaling in inflammation R Siebeler, MPJ de Winther, MA Hoeksema Journal of Allergy and Clinical Immunology 152 (2), 326-337, 2023 | 67 | 2023 |
| A PPARγ-Bnip3 axis couples adipose mitochondrial fusion-fission balance to systemic insulin sensitivity MJ Tol, R Ottenhoff, M Van Eijk, N Zelcer, J Aten, SM Houten, D Geerts, ... Diabetes 65 (9), 2591-2605, 2016 | 59 | 2016 |
| Nature and nurture of tissue-specific macrophage phenotypes MA Hoeksema, CK Glass Atherosclerosis 281, 159-167, 2019 | 53 | 2019 |
| Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia KAP Wijnands, MA Hoeksema, DM Meesters, NMS van den Akker, ... PloS one 9 (1), e86135, 2014 | 52 | 2014 |
| Somatic mosaicism reveals clonal distributions of neocortical development MW Breuss, X Yang, JCM Schlachetzki, D Antaki, AJ Lana, X Xu, ... Nature 604 (7907), 689-696, 2022 | 51 | 2022 |
| NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes J Fei, H Ishii, MA Hoeksema, F Meitinger, GA Kassavetis, CK Glass, ... Genes & development 32 (9-10), 682-694, 2018 | 51 | 2018 |
Menno de WintherProfessor of Vascular Immune Cell BiologyVerified email at amsterdamumc.nl
