| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ... Science 318 (5856), 1637-1640, 2007 | 1121 | 2007 |
| The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage GS Stewart, S Panier, K Townsend, AK Al-Hakim, NK Kolas, ES Miller, ... Cell 136 (3), 420-434, 2009 | 916 | 2009 |
| Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1 S Nakada, I Tai, S Panier, A Al-Hakim, S Iemura, YC Juang, L O’Donnell, ... Nature 466 (7309), 941-946, 2010 | 419 | 2010 |
| Human Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair T Yasuhara, R Kato, Y Hagiwara, B Shiotani, M Yamauchi, S Nakada, ... Cell 175 (2), 558-570. e11, 2018 | 364 | 2018 |
| PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint S Nakada, GI Chen, AC Gingras, D Durocher The EMBO Reports 9 (10), 1019-1026, 2008 | 294 | 2008 |
| BRCA1 directs the repair pathway to homologous recombination by promoting 53BP1 dephosphorylation M Isono, A Niimi, T Oike, Y Hagiwara, H Sato, R Sekine, Y Yoshida, ... Cell reports 18 (2), 520-532, 2017 | 255 | 2017 |
| Ubiquitination of DNA damage-stalled RNAPII promotes transcription-coupled repair Y Nakazawa, Y Hara, Y Oka, O Komine, D van den Heuvel, C Guo, ... Cell 180 (6), 1228-1244. e24, 2020 | 245 | 2020 |
| CRISPR-Cas3 induces broad and unidirectional genome editing in human cells H Morisaka, K Yoshimi, Y Okuzaki, P Gee, Y Kunihiro, E Sonpho, H Xu, ... Nature communications 10 (1), 5302, 2019 | 219 | 2019 |
| RFWD3-mediated ubiquitination promotes timely removal of both RPA and RAD51 from DNA damage sites to facilitate homologous recombination S Inano, K Sato, Y Katsuki, W Kobayashi, H Tanaka, K Nakajima, ... Molecular cell 66 (5), 622-634. e8, 2017 | 199 | 2017 |
| Fine-tuning of DNA damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice K Kato, K Nakajima, A Ui, Y Muto-Terao, H Ogiwara, S Nakada Molecular cell 53 (4), 617-630, 2014 | 107 | 2014 |
| BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes H Sasanuma, M Tsuda, S Morimoto, LK Saha, MM Rahman, Y Kiyooka, ... Proceedings of the National Academy of Sciences 115 (45), E10642-E10651, 2018 | 105 | 2018 |
| Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome Y Oka, M Hamada, Y Nakazawa, H Muramatsu, Y Okuno, K Higasa, ... Science Advances 6 (51), eabd7197, 2020 | 91 | 2020 |
| A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions P Kanellis, M Gagliardi, JP Banath, RK Szilard, S Nakada, S Galicia, ... Plos genetics 3 (8), e134, 2007 | 88 | 2007 |
| Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13 Y Sato, A Yamagata, S Goto-Ito, K Kubota, R Miyamoto, S Nakada, ... Journal of Biological Chemistry 287 (31), 25860-25868, 2012 | 87 | 2012 |
| RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1 S Nakada, RM Yonamine, K Matsuo Cancer research 72 (19), 4974-4983, 2012 | 76 | 2012 |
| Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism E Nitta, M Yamashita, K Hosokawa, MJ Xian, K Takubo, F Arai, S Nakada, ... Blood, The Journal of the American Society of Hematology 117 (16), 4169-4180, 2011 | 76 | 2011 |
| Ataxia‐telangiectasia‐mutated dependent phosphorylation of Artemis in response to DNA damage L Chen, T Morio, Y Minegishi, SI Nakada, M Nagasawa, K Komatsu, ... Cancer science 96 (2), 134-141, 2005 | 72 | 2005 |
| Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations S Nakada, Y Katsuki, I Imoto, T Yokoyama, M Nagasawa, J Inazawa, ... The Journal of clinical investigation 116 (1), 80-89, 2006 | 68 | 2006 |
| Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair K Nakajima, Y Zhou, A Tomita, Y Hirade, CB Gurumurthy, S Nakada Genome Research 28 (2), 223-230, 2018 | 56 | 2018 |
| Rad18 and Rnf8 facilitate homologous recombination by two distinct mechanisms, promoting Rad51 focus formation and suppressing the toxic effect of nonhomologous end joining S Kobayashi, Y Kasaishi, S Nakada, T Takagi, S Era, A Motegi, RK Chiu, ... Oncogene 34 (33), 4403-4411, 2015 | 53 | 2015 |
