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Mu-Sen Liu
Mu-Sen Liu
Senior Scientist I (Biochemistry) • Tango Therapeutics
Verified email at tangotx.com
Title
Cited by
Cited by
Year
Structural basis for mismatch surveillance by CRISPR–Cas9
JPK Bravo, MS Liu, GN Hibshman, TL Dangerfield, K Jung, RS McCool, ...
Nature 603 (7900), 343-347, 2022
3012022
Engineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA
MS Liu, S Gong, HH Yu, K Jung, KA Johnson, DW Taylor
Nature communications 11 (1), 3576, 2020
1152020
Kinetic characterization of Cas9 enzymes
MS Liu, S Gong, HH Yu, DW Taylor, KA Johnson
Methods in enzymology 616, 289-311, 2019
192019
Structural mechanism for the fidelity modulation of DNA polymerase λ
MS Liu, HY Tsai, XX Liu, MC Ho, WJ Wu, MD Tsai
Journal of the American Chemical Society 138 (7), 2389-2398, 2016
172016
Thermococcus sp. 9°N DNA polymerase exhibits 3′-esterase activity that can be harnessed for DNA sequencing
SW LinWu, YH Tu, TY Tsai, M Maestre-Reyna, MS Liu, WJ Wu, JY Huang, ...
Communications Biology 2 (1), 224, 2019
102019
Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of …
YR Lee, TS Lin, SJ Lai, MS Liu, MC Lai, NL Chan
Scientific reports 6 (1), 38071, 2016
102016
Basis for discrimination by engineered CRISPR/Cas9 enzymes
MS Liu, S Gong, HH Yu, K Jung, KA Johnson, DW Taylor
BioRxiv, 630509, 2019
52019
LIG1 Is a Synthetic Lethal Target in BRCA1 Mutant Cancers
LCM Martires, LG Ahronian, CB Pratt, NM Das, X Zhang, DA Whittington, ...
Molecular Cancer Therapeutics 24 (4), 618-627, 2025
42025
A duplexed high-throughput mass spectrometry assay for bifunctional POLB polymerase and lyase activity
ZA Gurard-Levin, B McMillan, DA Whittington, B Doyon, MD Scholle, ...
SLAS technology 29 (5), 100173, 2024
42024
POLB knockout is synthetic lethal with PARP inhibition leading to complete and durable responses in BRCA-mutant tumor xenografts
M Bandi, K Lazarides, J Engel, T Feng, M Meseonznik, A Choi, Y Yu, ...
Manuscript in Preparations. Published online, 2024
22024
Abstract C104: Hit finding and assay enablement for MGAT1, a novel glycosyl transferase involved in cancer cell immune evasion
KB Handing, MS Liu, DA Whittington, S Sun, R Salerno, WD Mallender, ...
Molecular Cancer Therapeutics 24 (10_Supplement), C104-C104, 2025
2025
Cas9 variants with improved specificity
DW Taylor, KA Johnson, JPK BRAVO, MS LIU, T DANGERFIELD, ...
US Patent App. 18/691,246, 2025
2025
Cas9 variants with improved specificity
DW Taylor, KA Johnson, JPK BRAVO, T DANGERFIELD, GN HIBSHMAN
2023
Structural basis for mismatch surveillance by CRISPR-Cas9 (vol 603, pg 343, 2022)
JPK Bravo, MS Liu, GN Hibshman, TL Dangerfield, K Jung, RS McCool, ...
NATURE 604 (7904), E10-E10, 2022
2022
Kinetic Basis for Improved Specificity of CRISPR/Cas9 High Fidelity Variants
MS Liu, S Gong, HH Yu, DW Taylor, KA Johnson
The FASEB Journal 33 (S1), 620.4-620.4, 2019
2019
DNA 聚合酶 λ 結構機制探討之忠實度調節
劉沐森
國立臺灣大學生化科學研究所學位論文, 1-111, 2016
2016
SLAS Technology
ZA Gurard-Levin, B McMillan, DA Whittington, B Doyon, MD Scholle, ...
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Articles 1–17