| Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by β-amyloid peptides via p38 mitogen-activated protein kinase pathway PM Canas, LO Porciúncula, GMA Cunha, CG Silva, NJ Machado, ... Journal of Neuroscience 29 (47), 14741-14751, 2009 | 431 | 2009 |
| Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress MP Kaster, NJ Machado, HB Silva, A Nunes, AP Ardais, M Santana, ... Proceedings of the National Academy of Sciences 112 (25), 7833-7838, 2015 | 386 | 2015 |
| Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes RG Tavares, CI Tasca, CES Santos, LB Alves, LO Porciúncula, ... Neurochemistry international 40 (7), 621-627, 2002 | 369 | 2002 |
| Neuroprotection by caffeine and adenosine A2A receptor blockade of β-amyloid neurotoxicity OP Dall'Igna, LO Porciuncula, DO Souza, RA Cunha, DR Lara British journal of pharmacology 139 (8), 1571, 2003 | 276 | 2003 |
| Caffeine Consumption Prevents Memory Impairment, Neuronal Damage, and Adenosine A2A Receptors Upregulation in the Hippocampus of a Rat Model of … J Espinosa, A Rocha, F Nunes, MS Costa, V Schein, V Kazlauckas, ... Journal of Alzheimer’s Disease 34 (2), 509-518, 2013 | 179 | 2013 |
| Coffee, caffeine, chlorogenic acid, and the purinergic system N Stefanello, RM Spanevello, S Passamonti, L Porciúncula, CD Bonan, ... Food and Chemical Toxicology 123, 298-313, 2019 | 175 | 2019 |
| Caffeine prevents disruption of memory consolidation in the inhibitory avoidance and novel object recognition tasks by scopolamine in adult mice PH Botton, MS Costa, AP Ardais, S Mioranzza, DO Souza, JBT da Rocha, ... Behavioural brain research 214 (2), 254-259, 2010 | 170 | 2010 |
| Caffeine prevents age-associated recognition memory decline and changes brain-derived neurotrophic factor and tirosine kinase receptor (TrkB) content in mice MS Costa, PH Botton, S Mioranzza, DO Souza, LO Porciúncula Neuroscience 153 (4), 1071-1078, 2008 | 151 | 2008 |
| Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons LO Porciúncula, JBT Rocha, CR Boeck, D Vendite, DO Souza Neuroscience letters 299 (3), 217-220, 2001 | 135 | 2001 |
| Exercise affects glutamate receptors in postsynaptic densities from cortical mice brain MO Dietrich, CE Mantese, LO Porciuncula, G Ghisleni, L Vinade, ... Brain research 1065 (1-2), 20-25, 2005 | 130 | 2005 |
| Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus MS Costa, PH Botton, S Mioranzza, AP Ardais, JD Moreira, DO Souza, ... Neurochemistry international 53 (3-4), 89-94, 2008 | 128 | 2008 |
| Long‐term Effect of Convulsive Behavior on the Density of Adenosine A1 and A2A Receptors in the Rat Cerebral Cortex N Rebola, LO Porciúncula, LV Lopes, CR Oliveira, P Soares‐da‐Silva, ... Epilepsia 46, 159-165, 2005 | 122 | 2005 |
| Enriched environment effects on behavior, memory and BDNF in low and high exploratory mice V Kazlauckas, N Pagnussat, S Mioranzza, E Kalinine, F Nunes, ... Physiology & behavior 102 (5), 475-480, 2011 | 108 | 2011 |
| Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation AP Simões, CG Silva, JM Marques, D Pochmann, LO Porciúncula, ... Cell Death & Disease 9 (3), 297, 2018 | 106 | 2018 |
| Anti‐nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors AP Schmidt, AE Böhmer, C Antunes, C Schallenberger, LO Porciúncula, ... British Journal of Pharmacology 156 (1), 163-172, 2009 | 106 | 2009 |
| Diphenyl diselenide protects rat hippocampal slices submitted to oxygen–glucose deprivation and diminishes inducible nitric oxide synthase immunocontent G Ghisleni, LO Porciuncula, H Cimarosti, JBT Rocha, CG Salbego, ... Brain research 986 (1-2), 196-199, 2003 | 103 | 2003 |
| Adenosine A2A receptors are necessary and sufficient to trigger memory impairment in adult mice N Pagnussat, AS Almeida, DM Marques, F Nunes, GC Chenet, ... British Journal of Pharmacology 172 (15), 3831-3845, 2015 | 102 | 2015 |
| Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for … AS Freitas, AS Prestes, C Wagner, JH Sudati, D Alves, LO Porciúncula, ... Molecules 15 (11), 7699-7714, 2010 | 96 | 2010 |
| Neuroprotection by caffeine and adenosine A2A receptor blockade of β‐amyloid neurotoxicity OP Dall'lgna, LO Porciúncula, DO Souza, RA Cunha, DR Lara British journal of pharmacology 138 (7), 1207-1209, 2003 | 92 | 2003 |
| Repeated restraint stress alters hippocampal glutamate uptake and release in the rat FU Fontella, DA Vendite, AS Tabajara, LO Porciúncula, ILS Torres, ... Neurochemical research 29 (9), 1703-1709, 2004 | 87 | 2004 |
