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David Schlaepfer
David Schlaepfer
Moores UCSD Cancer Center
Verified email at ucsd.edu - Homepage
Title
Cited by
Cited by
Year
Focal adhesion kinase: in command and control of cell motility
SK Mitra, DA Hanson, DD Schlaepfer
Nature reviews Molecular cell biology 6 (1), 56-68, 2005
33032005
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
DD Schlaepfer, SK Hanks, T Hunter, P Geer
Nature 372 (6508), 786-791, 1994
21381994
Integrin-regulated FAK–Src signaling in normal and cancer cells
SK Mitra, DD Schlaepfer
Current opinion in cell biology 18 (5), 516-523, 2006
19712006
FAK integrates growth-factor and integrin signals to promote cell migration
DJ Sieg, CR Hauck, D Ilic, CK Klingbeil, E Schaefer, CH Damsky, ...
Nature cell biology 2 (5), 249-256, 2000
15852000
Signaling through focal adhesion kinase
DD Schlaepfer, CR Hauck, DJ Sieg
Progress in biophysics and molecular biology 71 (3-4), 435-478, 1999
15551999
FAK in cancer: mechanistic findings and clinical applications
FJ Sulzmaier, C Jean, DD Schlaepfer
Nature reviews cancer 14 (9), 598-610, 2014
15302014
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
DJ Sieg, CR Hauck, DD Schlaepfer
Journal of cell science 112 (16), 2677-2691, 1999
9121999
Differential regulation of cell motility and invasion by FAK
DA Hsia, SK Mitra, CR Hauck, DN Streblow, JA Nelson, D Ilic, S Huang, ...
The Journal of cell biology 160 (5), 753-767, 2003
7462003
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation
AM Pasapera, IC Schneider, E Rericha, DD Schlaepfer, CM Waterman
Journal of Cell Biology 188 (6), 877-890, 2010
7012010
Integrin signalling and tyrosine phosphorylation: just the FAKs?
DD Schlaepfer, T Hunter
Trends in cell biology 8 (4), 151-157, 1998
6951998
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ...
Nature medicine 22 (5), 497-505, 2016
6682016
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
XD Ren, WB Kiosses, DJ Sieg, CA Otey, DD Schlaepfer, MA Schwartz
Journal of cell science 113 (20), 3673-3678, 2000
6372000
Control of motile and invasive cell phenotypes by focal adhesion kinase
DD Schlaepfer, SK Mitra, D Ilic
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1692 (2-3), 77-102, 2004
6292004
Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases
DD Schlaepfer, T Hunter
Molecular and cellular biology 16 (10), 5623-5633, 1996
6151996
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
D Ilić, EAC Almeida, DD Schlaepfer, P Dazin, S Aizawa, CH Damsky
The Journal of cell biology 143 (2), 547-560, 1998
6121998
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation
ST Lim, XL Chen, Y Lim, DA Hanson, TT Vo, K Howerton, N Larocque, ...
Molecular cell 29 (1), 9-22, 2008
6032008
Fibronectin-Stimulated Signaling from a Focal Adhesion Kinase–c-Src Complex: Involvement of the Grb2, p130cas, and Nck Adaptor Proteins
DD Schlaepfer, MA Broome, T Hunter
Molecular and cellular biology 17 (3), 1702-1713, 1997
5921997
Multiple connections link FAK to cell motility and invasion
DD Schlaepfer, SK Mitra
Current opinion in genetics & development 14 (1), 92-101, 2004
5602004
Fluid shear stress activation of focal adhesion kinase: linking to mitogen-activated protein kinases
S Li, M Kim, YL Hu, S Jalali, DD Schlaepfer, T Hunter, S Chien, JYJ Shyy
Journal of Biological Chemistry 272 (48), 30455-30462, 1997
5471997
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src-and focal adhesion kinase-initiated tyrosine …
DD Schlaepfer, KC Jones, T Hunter
Molecular and cellular biology 18 (5), 2571-2585, 1998
5381998
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Articles 1–20