| The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases R Chowdhury, KK Yeoh, YM Tian, L Hillringhaus, EA Bagg, NR Rose, ... EMBO reports 12 (5), 463, 2011 | 1258 | 2011 |
| Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors YM Tian, KK Yeoh, MK Lee, T Eriksson, BM Kessler, HB Kramer, ... Journal of biological chemistry 286 (15), 13041-13051, 2011 | 236 | 2011 |
| 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ... Chemical science 4 (8), 3110-3117, 2013 | 194 | 2013 |
| Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ... Journal of medicinal chemistry 55 (14), 6639-6643, 2012 | 185 | 2012 |
| Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents E Flashman, SL Davies, KK Yeoh, CJ Schofield Biochemical journal 427 (1), 135-142, 2010 | 179 | 2010 |
| Structural basis for inhibition of the fat mass and obesity associated protein (FTO) WS Aik, M Demetriades, MKK Hamdan, EAL Bagg, KK Yeoh, C Lejeune, ... Journal of medicinal chemistry 56 (9), 3680-3688, 2013 | 174 | 2013 |
| Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases R Chowdhury, JI Candela-Lena, MC Chan, DJ Greenald, KK Yeoh, ... ACS chemical biology 8 (7), 1488-1496, 2013 | 155 | 2013 |
| Metabolic adaptation to chronic hypoxia in cardiac mitochondria LC Heather, MA Cole, JJ Tan, LJA Ambrose, S Pope, AH Abd-Jamil, ... Basic research in cardiology 107 (3), 268, 2012 | 130 | 2012 |
| Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors SC Tan, CA Carr, KK Yeoh, CJ Schofield, KE Davies, K Clarke Molecular biology reports 39 (4), 4857-4867, 2012 | 115 | 2012 |
| Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors M Demetriades, IKH Leung, R Chowdhury, MC Chan, MA McDonough, ... Angewandte Chemie International Edition 51 (27), 6672-6675, 2012 | 108 | 2012 |
| On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury MA Cole, AH Abd Jamil, LC Heather, AJ Murray, ER Sutton, M Slingo, ... The faseb journal 30 (8), 2684, 2016 | 87 | 2016 |
| HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice RL Chen, OO Ogunshola, KK Yeoh, A Jani, M Papadakis, S Nagel, ... Journal of neurochemistry 131 (2), 177-189, 2014 | 57 | 2014 |
| Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure CJ Stubbs, C Loenarz, J Mecinović, KK Yeoh, N Hindley, BM Liénard, ... Journal of medicinal chemistry 52 (9), 2799-2805, 2009 | 56 | 2009 |
| Probing replacement of pyrophosphate via click chemistry; synthesis of UDP-sugar analogues as potential glycosyl transferase inhibitors KK Yeoh, TD Butters, BL Wilkinson, AJ Fairbanks Carbohydrate research 344 (5), 586-591, 2009 | 56 | 2009 |
| Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion KK Yeoh, MC Chan, A Thalhammer, M Demetriades, R Chowdhury, ... Organic & biomolecular chemistry 11 (5), 732-745, 2013 | 45 | 2013 |
| Preconditioning of cardiosphere-derived cells with hypoxia or prolyl-4-hydroxylase inhibitors increases stemness and decreases reliance on oxidative metabolism SC Tan, RSM Gomes, KK Yeoh, F Perbellini, S Malandraki-Miller, ... Cell transplantation 25 (1), 35-53, 2016 | 43 | 2016 |
| Using NMR solvent water relaxation to investigate metalloenzyme− ligand binding interactions IKH Leung, E Flashman, KK Yeoh, CJ Schofield, TDW Claridge Journal of medicinal chemistry 53 (2), 867-875, 2010 | 41 | 2010 |
| Pharmacotherapeutic potential of natural products to target the SARS-CoV-2 PLpro using molecular screening and simulation approaches AM Sayaf, H Ahmad, MA Aslam, SA Ghani, S Bano, Q Yousafi, ... Applied Biochemistry and Biotechnology 195 (11), 6959-6978, 2023 | 18 | 2023 |
| Exploring the natural products chemical space through a molecular search to discover potential inhibitors that target the hypoxia-inducible factor (HIF) prolyl hydroxylase … AM Sayaf, S Ullah Khalid, JA Hameed, A Alshammari, A Khan, ... Frontiers in Pharmacology 14, 1202128, 2023 | 18 | 2023 |
| Molecular exploration of natural and synthetic compounds databases for promising hypoxia inducible factor (HIF) Prolyl-4-hydroxylase domain (PHD) inhibitors using molecular … AM Sayaf, K Kousar, M Suleman, NA Albekairi, AR Alshammari, ... BMC chemistry 18 (1), 236, 2024 | 8 | 2024 |
Eleanor BaggUniversity of OxfordVerified email at lincoln.oxon.org
