| Molecular dynamics simulation for all SA Hollingsworth, RO Dror Neuron 99 (6), 1129-1143, 2018 | 3532 | 2018 |
| A fresh look at the Ramachandran plot and the occurrence of standard structures in proteins SA Hollingsworth, PA Karplus Biomolecular concepts 1 (3-4), 271, 2010 | 476 | 2010 |
| Structure of a signaling cannabinoid receptor 1-G protein complex KK Kumar, M Shalev-Benami, MJ Robertson, H Hu, SD Banister, ... Cell 176 (3), 448-458. e12, 2019 | 464 | 2019 |
| Molecular mechanism of GPCR-mediated arrestin activation NR Latorraca, JK Wang, B Bauer, RJL Townshend, SA Hollingsworth, ... Nature 557 (7705), 452-456, 2018 | 234 | 2018 |
| How GPCR phosphorylation patterns orchestrate arrestin-mediated signaling NR Latorraca, M Masureel, SA Hollingsworth, FM Heydenreich, ... Cell 183 (7), 1813-1825. e18, 2020 | 177 | 2020 |
| Structure and mechanism of the cation–chloride cotransporter NKCC1 TA Chew, BJ Orlando, J Zhang, NR Latorraca, A Wang, SA Hollingsworth, ... Nature 572 (7770), 488-492, 2019 | 140 | 2019 |
| Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation C Hong, NJ Byrne, B Zamlynny, S Tummala, L Xiao, JM Shipman, ... Nature communications 12 (1), 815, 2021 | 106 | 2021 |
| Gi-and Gs-coupled GPCRs show different modes of G-protein binding N Van Eps, C Altenbach, LN Caro, NR Latorraca, SA Hollingsworth, ... Proceedings of the National Academy of Sciences 115 (10), 2383-2388, 2018 | 106 | 2018 |
| Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs SA Hollingsworth, B Kelly, C Valant, JA Michaelis, O Mastromihalis, ... Nature Communications 10 (1), 3289, 2019 | 80 | 2019 |
| Conformational selectivity in cytochrome P450 redox partner interactions SA Hollingsworth, D Batabyal, BD Nguyen, TL Poulos Proceedings of the National Academy of Sciences 113 (31), 8723-8728, 2016 | 72 | 2016 |
| Uncovering patterns of atomic interactions in static and dynamic structures of proteins AJ Venkatakrishnan, R Fonseca, AK Ma, SA Hollingsworth, ... BioRxiv, 840694, 2019 | 55 | 2019 |
| On the occurrence of linear groups in proteins SA Hollingsworth, DS Berkholz, PA Karplus Protein Science 18 (6), 1321-1325, 2009 | 50 | 2009 |
| Leveraging nonstructural data to predict structures and affinities of protein–ligand complexes JM Paggi, JA Belk, SA Hollingsworth, N Villanueva, AS Powers, MJ Clark, ... Proceedings of the National Academy of Sciences 118 (51), e2112621118, 2021 | 37 | 2021 |
| Small molecule agonists of toll-like receptors 7 and 8: a patent review 2014–2020 ME Kieffer, AM Patel, SA Hollingsworth, WM Seganish Expert Opinion on Therapeutic Patents 30 (11), 825-845, 2020 | 30 | 2020 |
| Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists M Wu, E Carballo-Jane, H Zhou, P Zafian, G Dai, M Liu, J Lao, T Kelly, ... Nature Communications 13 (1), 942, 2022 | 29 | 2022 |
| Delineating the ligand–receptor interactions that lead to biased signaling at the μ-opioid receptor B Kelly, SA Hollingsworth, DC Blakemore, RM Owen, RI Storer, NA Swain, ... Journal of Chemical Information and Modeling 61 (7), 3696-3707, 2021 | 27 | 2021 |
| (φ, ψ) 2 motifs: a purely conformation-based fine-grained enumeration of protein parts at the two-residue level SA Hollingsworth, MC Lewis, DS Berkholz, WK Wong, PA Karplus Journal of Molecular Biology 416 (1), 78-93, 2012 | 27 | 2012 |
| Molecular dynamics of the P 450cam–P dx complex reveals complex stability and novel interface contacts SA Hollingsworth, TL Poulos Protein Science 24 (1), 49-57, 2015 | 26 | 2015 |
| Crystal structure of cindoxin, the P450cin redox partner Y Madrona, SA Hollingsworth, S Tripathi, JB Fields, JCN Rwigema, ... Biochemistry 53 (9), 1435-1446, 2014 | 26 | 2014 |
| Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors JK Holden, S Kang, SA Hollingsworth, H Li, N Lim, S Chen, H Huang, ... Journal of Medicinal Chemistry, 2014 | 25 | 2014 |
