| Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors B Schoeberl, C Eichler-Jonsson, ED Gilles, G Müller Nature biotechnology 20 (4), 370-375, 2002 | 1281 | 2002 |
| Systems biology and combination therapy in the quest for clinical efficacy JB Fitzgerald, B Schoeberl, UB Nielsen, PK Sorger Nature chemical biology 2 (9), 458-466, 2006 | 723 | 2006 |
| Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data WW Chen, B Schoeberl, PJ Jasper, M Niepel, UB Nielsen, ... Molecular systems biology 5 (1), 239, 2009 | 492 | 2009 |
| Therapeutically targeting ErbB3: A key node in ligand-induced activation of the ErbB receptor–PI3K axis B Schoeberl, EA Pace, JB Fitzgerald, BD Harms, L Xu, L Nie, B Linggi, ... Science signaling 2 (77), ra31-ra31, 2009 | 445 | 2009 |
| Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3 CF McDonagh, A Huhalov, BD Harms, S Adams, V Paragas, S Oyama, ... Molecular cancer therapeutics 11 (3), 582-593, 2012 | 373 | 2012 |
| An ErbB3 antibody, MM-121, is active in cancers with ligand-dependent activation B Schoeberl, AC Faber, D Li, MC Liang, K Crosby, M Onsum, ... Cancer research 70 (6), 2485-2494, 2010 | 334 | 2010 |
| Estimation of immune cell content in tumour tissue using single-cell RNA-seq data M Schelker, S Feau, J Du, N Ranu, E Klipp, G MacBeath, B Schoeberl, ... Nature communications 8 (1), 2032, 2017 | 294 | 2017 |
| An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells Q Sheng, X Liu, E Fleming, K Yuan, H Piao, J Chen, Z Moustafa, ... Cancer cell 17 (3), 298-310, 2010 | 283 | 2010 |
| Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ... Bioinformatics 31 (21), 3558-3560, 2015 | 277 | 2015 |
| Control of MAPK signalling: from complexity to what really matters JJ Hornberg, B Binder, FJ Bruggeman, B Schoeberl, R Heinrich, ... Oncogene 24 (36), 5533-5542, 2005 | 258 | 2005 |
| Effects of insulin-like growth factor-1 and dexamethasone on cytokine-challenged cartilage: relevance to post-traumatic osteoarthritis Y Li, Y Wang, S Chubinskaya, B Schoeberl, E Florine, P Kopesky, ... Osteoarthritis and cartilage 23 (2), 266-274, 2015 | 151 | 2015 |
| MM-141, an IGF-IR–and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors JB Fitzgerald, BW Johnson, J Baum, S Adams, S Iadevaia, J Tang, ... Molecular cancer therapeutics 13 (2), 410-425, 2014 | 129 | 2014 |
| Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines M Niepel, M Hafner, EA Pace, M Chung, DH Chai, L Zhou, B Schoeberl, ... Science signaling 6 (294), ra84-ra84, 2013 | 117 | 2013 |
| Competing docking interactions can bring about bistability in the MAPK cascade S Legewie, B Schoeberl, N Blüthgen, H Herzel Biophysical journal 93 (7), 2279-2288, 2007 | 109 | 2007 |
| Transport and thermal properties of poly (ether imide)/acetylene-terminated monomer blends ME Rezac, B Schöberl Journal of Membrane Science 156 (2), 211-222, 1999 | 99 | 1999 |
| Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies Y Zhou, AL Goenaga, BD Harms, H Zou, J Lou, F Conrad, GP Adams, ... Molecular cancer therapeutics 11 (7), 1467-1476, 2012 | 91 | 2012 |
| Autocrine signaling is a key regulatory element during osteoclastogenesis P Kopesky, K Tiedemann, D Alkekhia, C Zechner, B Millard, B Schoeberl, ... Biology open 3 (8), 767-776, 2014 | 79 | 2014 |
| Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121) B Schoeberl, A Kudla, K Masson, A Kalra, M Curley, G Finn, E Pace, ... NPJ systems biology and applications 3 (1), 1-17, 2017 | 74 | 2017 |
| Influence of crosslinking technique on the physical and transport properties of ethynyl-terminated monomer/polyetherimide asymmetric membranes CN Dudley, B Schöberl, GK Sturgill, HW Beckham, ME Rezac Journal of Membrane Science 191 (1-2), 1-11, 2001 | 72 | 2001 |
| HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B DC Kirouac, J Du, J Lahdenranta, MD Onsum, UB Nielsen, B Schoeberl, ... PLoS computational biology 12 (4), e1004827, 2016 | 68 | 2016 |
