| Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children A Ramaswamy, NN Brodsky, TS Sumida, M Comi, H Asashima, ... Immunity 54 (5), 1083-1095. e7, 2021 | 296 | 2021 |
| Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19 A Unterman, TS Sumida, N Nouri, X Yan, AY Zhao, V Gasque, JC Schupp, ... Nature Communications 13 (1), 1-23, 2022 | 196 | 2022 |
| Effects of inversions on within-and between-species recombination and divergence LS Stevison, KB Hoehn, MAF Noor Genome biology and evolution 3, 830-841, 2011 | 176 | 2011 |
| Mutant EZH2 induces a pre-malignant lymphoma niche by reprogramming the immune response W Béguelin, M Teater, C Meydan, KB Hoehn, JM Phillip, AA Soshnev, ... Cancer cell 37 (5), 655-673. e11, 2020 | 169 | 2020 |
| The diversity and molecular evolution of B-cell receptors during infection KB Hoehn, A Fowler, G Lunter, OG Pybus Molecular biology and evolution 33 (5), 1147-1157, 2016 | 132 | 2016 |
| Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination KB Hoehn, JA Vander Heiden, JQ Zhou, G Lunter, OG Pybus, ... Proceedings of the National Academy of Sciences 116 (45), 22664-22672, 2019 | 129 | 2019 |
| Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation JW Austin, CM Buckner, L Kardava, W Wang, X Zhang, VA Melson, ... Science translational medicine 11 (520), eaax0904, 2019 | 113 | 2019 |
| Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice KM Nickerson, S Smita, KB Hoehn, AD Marinov, KB Thomas, JT Kos, ... Journal of Experimental Medicine 220 (5), e20221346, 2023 | 108 | 2023 |
| Phylogenetic analysis of migration, differentiation, and class switching in B cells KB Hoehn, OG Pybus, SH Kleinstein PLoS computational biology 18 (4), e1009885, 2022 | 101 | 2022 |
| CD23+IgG1+ memory B cells are poised to switch to pathogenic IgE production in food allergy M Ota, KB Hoehn, W Fernandes-Braga, T Ota, CJ Aranda, S Friedman, ... Science translational medicine 16 (733), eadi0673, 2024 | 94* | 2024 |
| A phylogenetic codon substitution model for antibody lineages KB Hoehn, G Lunter, OG Pybus Genetics 206 (1), 417-427, 2017 | 82 | 2017 |
| Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children Q Xu, P Milanez-Almeida, AJ Martins, AJ Radtke, KB Hoehn, C Oguz, ... Nature immunology 24 (1), 186-199, 2023 | 80 | 2023 |
| Single-cell repertoire tracing identifies rituximab-resistant B cells during myasthenia gravis relapses R Jiang, ML Fichtner, KB Hoehn, MC Pham, P Stathopoulos, RJ Nowak, ... JCI insight 5 (14), e136471, 2020 | 70 | 2020 |
| Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis R Jiang, KB Hoehn, CS Lee, MC Pham, RJ Homer, FC Detterbeck, I Aban, ... Proceedings of the National Academy of Sciences 117 (48), 30649-30660, 2020 | 64 | 2020 |
| Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving KB Hoehn, JS Turner, FI Miller, R Jiang, OG Pybus, AH Ellebedy, ... Elife 10, e70873, 2021 | 55 | 2021 |
| BTG1 mutation yields supercompetitive B cells primed for malignant transformation C Mlynarczyk, M Teater, J Pae, CR Chin, L Wang, T Arulraj, D Barisic, ... Science 379 (6629), eabj7412, 2023 | 48 | 2023 |
| Distinct B cell repertoires characterize patients with mild and severe COVID-19 KB Hoehn, P Ramanathan, A Unterman, TS Sumida, H Asashima, ... The Journal of Immunology 206 (12), 2785-2790, 2021 | 45 | 2021 |
| Dynamics of immunoglobulin sequence diversity in HIV-1 infected individuals KB Hoehn, A Gall, R Bashford-Rogers, SJ Fidler, S Kaye, JN Weber, ... Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015 | 42 | 2015 |
| PD-1highCXCR5–CD4+ peripheral helper T cells promote CXCR3+ plasmablasts in human acute viral infection H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, ... Cell Reports 42 (1), 2023 | 40 | 2023 |
| Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapy ML Fichtner, KB Hoehn, EE Ford, M Mane-Damas, S Oh, P Waters, ... Acta neuropathologica communications 10 (1), 154, 2022 | 40 | 2022 |
Steven H. KleinsteinProfessor, Departments of Pathology and Immunobiology, Yale School of MedicineVerified email at yale.edu
