| An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel WJ Crumb Jr, J Vicente, L Johannesen, DG Strauss Journal of pharmacological and toxicological methods 81, 251-262, 2016 | 321 | 2016 |
| Differentiating Drug‐Induced Multichannel Block on the Electrocardiogram: Randomized Study of Dofetilide, Quinidine, Ranolazine, and Verapamil L Johannesen, J Vicente, JW Mason, C Sanabria, K Waite‐Labott, ... Clinical Pharmacology & Therapeutics 96 (5), 549-558, 2014 | 291 | 2014 |
| Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias K Blinova, J Stohlman, J Vicente, D Chan, L Johannesen, ... Toxicological Sciences 155 (1), 234-247, 2017 | 289 | 2017 |
| Results From the IQ‐CSRC Prospective Study Support Replacement of the Thorough QT Study by QT Assessment in the Early Clinical Phase B Darpo, C Benson, C Dota, G Ferber, C Garnett, CL Green, V Jarugula, ... Clinical Pharmacology & Therapeutics 97 (4), 326-335, 2015 | 196 | 2015 |
| Late sodium current block for drug‐induced long QT syndrome: Results from a prospective clinical trial L Johannesen, J Vicente, JW Mason, C Erato, C Sanabria, K Waite‐Labott, ... Clinical Pharmacology & Therapeutics 99 (2), 214-223, 2016 | 163 | 2016 |
| Mechanistic Model‐Informed Proarrhythmic Risk Assessment of Drugs: Review of the “CiPA” Initiative and Design of a Prospective Clinical Validation Study J Vicente, R Zusterzeel, L Johannesen, J Mason, P Sager, V Patel, ... Clinical Pharmacology & Therapeutics 103 (1), 54-66, 2018 | 145 | 2018 |
| Comprehensive T wave Morphology Assessment in a Randomized Clinical Study of Dofetilide, Quinidine, Ranolazine, and Verapamil J Vicente, L Johannesen, JW Mason, WJ Crumb, E Pueyo, N Stockbridge, ... Journal of the American Heart Association 4 (4), e001615, 2015 | 145 | 2015 |
| Common Genetic Variant Risk Score Is Associated With Drug-Induced QT Prolongation and Torsade de Pointes Risk DG Strauss, J Vicente, L Johannesen, K Blinova, JW Mason, P Weeke, ... Circulation 135 (14), 1300-1310, 2017 | 137 | 2017 |
| The IQ‐CSRC Prospective Clinical Phase 1 Study:“Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?” B Darpo, N Sarapa, C Garnett, C Benson, C Dota, G Ferber, V Jarugula, ... Annals of Noninvasive Electrocardiology 19 (1), 70-81, 2014 | 117 | 2014 |
| Improving the assessment of heart toxicity for all new drugs through translational regulatory science L Johannesen, J Vicente, RA Gray, L Galeotti, Z Loring, CE Garnett, ... Clinical Pharmacology & Therapeutics 95 (5), 501-508, 2014 | 103 | 2014 |
| Mechanisms of sex and age differences in ventricular repolarization in humans J Vicente, L Johannesen, L Galeotti, DG Strauss American heart journal 168 (5), 749-756. e3, 2014 | 101 | 2014 |
| Assessment of Multi‐Ion Channel Block in a Phase I Randomized Study Design: Results of the Ci PA Phase I ECG Biomarker Validation Study J Vicente, R Zusterzeel, L Johannesen, R Ochoa‐Jimenez, JW Mason, ... Clinical Pharmacology & Therapeutics 105 (4), 943-953, 2019 | 94 | 2019 |
| Automatic ECG quality scoring methodology: mimicking human annotators L Johannesen, L Galeotti Physiological Measurement 33 (9), 1479, 2012 | 83 | 2012 |
| A Comparison of IIR and Wavelet Filtering for Noise Reduction of the ECG JS Sørensen, L Johannesen, USL Grove, K Lundhus, JP Couderc, C Graff Computing in Cardiology, 2010, 489-492, 2010 | 57 | 2010 |
| Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block J Vicente, L Johannesen, M Hosseini, JW Mason, PT Sager, E Pueyo, ... PLOS ONE 11 (12), e0163619, 2016 | 46 | 2016 |
| Assessment of ECG quality on an android platform L Johannesen Computing in Cardiology 38, 433-436, 2011 | 46 | 2011 |
| Automated Algorithm for J-Tpeak and Tpeak-Tend Assessment of Drug-Induced Proarrhythmia Risk L Johannesen, J Vicente, M Hosseini, DG Strauss PLOS ONE 11 (12), e0166925, 2016 | 44 | 2016 |
| Assessing ECG signal quality indices to discriminate ECGs with artefacts from pathologically different arrhythmic ECGs C Daluwatte, L Johannesen, L Galeotti, J Vicente, DG Strauss, CG Scully Physiological Measurement 37 (8), 1370, 2016 | 41 | 2016 |
| Universal correction for QT/RR hysteresis M Malik, L Johannesen, K Hnatkova, N Stockbridge Drug safety 39 (6), 577-588, 2016 | 35 | 2016 |
| Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block PN Tran, J Sheng, AL Randolph, CA Baron, N Thiebaud, M Ren, M Wu, ... Plos one 15 (11), e0241362, 2020 | 34 | 2020 |