| Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ... Experimental & molecular medicine 53 (5), 956-972, 2021 | 86 | 2021 |
| Identification of novel discoidin domain receptor 1 (DDR1) inhibitors using E-pharmacophore modeling, structure-based virtual screening, molecular dynamics simulation and MM … H Nada, K Lee, L Gotina, AN Pae, A Elkamhawy Computers in Biology and Medicine 142, 105217, 2022 | 66 | 2022 |
| Design, synthesis and biological evaluation of new HDAC1 and HDAC2 inhibitors endowed with ligustrazine as a novel cap moiety MM Al-Sanea, L Gotina, MFA Mohamed, D Grace Thomas Parambi, ... Drug design, development and therapy, 497-508, 2020 | 48 | 2020 |
| Highly potent, selective, and competitive indole-based MAO-B inhibitors protect PC12 cells against 6-hydroxydopamine-and rotenone-induced oxidative stress MH Elsherbeny, J Kim, NA Gouda, L Gotina, J Cho, AN Pae, K Lee, ... Antioxidants 10 (10), 1641, 2021 | 31 | 2021 |
| Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington’s disease mouse model YJ Hwang, SJ Hyeon, Y Kim, S Lim, MY Lee, J Kim, AM Londhe, L Gotina, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 856-868, 2021 | 17 | 2021 |
| Discovery of 3, 4-dichloro-N-(1H-indol-5-yl) benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action A Elkamhawy, HJ Kim, MH Elsherbeny, S Paik, JH Park, L Gotina, ... Bioorganic Chemistry 116, 105352, 2021 | 14 | 2021 |
| Pharmacophore-based virtual screening of novel competitive inhibitors of the neurodegenerative disease target kynurenine-3-monooxygenase L Gotina, SH Seo, CW Kim, SM Lim, AN Pae Molecules 26 (11), 3314, 2021 | 12 | 2021 |
| Structural determinants for activation of the Tau kinase CDK5 by the serotonin receptor 5-HT7R J Ackmann, A Brüge, L Gotina, S Lim, K Jahreis, AL Vollbrecht, YK Kim, ... Cell Communication and Signaling 22 (1), 233, 2024 | 9 | 2024 |
| Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants EH Lee, J Park, L Gotina, YE Han, ANI Viswanath, S Yoo, B Moon, ... Biomedicine & Pharmacotherapy 165, 115139, 2023 | 7 | 2023 |
| NeuM: A Neuron‐Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin‐Mediated Endocytosis in Primary Neurons Y Sung, L Gotina, KH Kim, JY Lee, S Shin, H Aziz, DM Kang, X Liu, ... Angewandte Chemie 136 (3), e202312942, 2024 | 6 | 2024 |
| Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis E Cha, J Kim, L Gotina, J Kim, HJ Kim, SH Seo, JE Park, J Joo, M Kang, ... Journal of Medicinal Chemistry 66 (15), 10381-10412, 2023 | 6 | 2023 |
| Structural hybridization for inhibitors of the interaction between NRF2 and Keap1 DH Lee, SH Seo, L Gotina, AN Pae, SM Lim Bulletin of the Korean Chemical Society, 1-6, 2022 | 4 | 2022 |
| Novel hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof AN Pae, YK KIM, SM Lim, S LIM, J SEONG, JW Lee, JY Song, S Shin, ... US Patent App. 17/415,382, 2022 | 3 | 2022 |
| Molecular characterization of hepatitis C virus for developed antiviral agents resistance mutations and new insights into in-silico prediction studies MMA El-Sokkary, L Gotina, MM Al-Sanea, AN Pae, RM Elbargisy Infection and Drug Resistance, 4235-4248, 2020 | 3 | 2020 |
| Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases W Won, EH Lee, L Gotina, H Chun, JH Lee, M Bhalla, U Park, D Kim, ... Signal Transduction and Targeted Therapy 10 (1), 270, 2025 | 2 | 2025 |
| Discovery of Novel β-Arrestin Biased Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis CY Lee, L Gotina, J Kim, J Kim, JY Ahn, WS Son, SH Seo, J Park, M Kang, ... Journal of Medicinal Chemistry 68 (17), 18289-18313, 2025 | | 2025 |
Ahmed ElkamhawyDepartment of Pharmaceutical Organic chemistry, Faculty o Pharmacy, Mansoura UniversityVerified email at mans.edu.eg
