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Prakash Manikwar
Prakash Manikwar
Scientist
Verified email at medimmune.com
Title
Cited by
Cited by
Year
Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, HS Samra, HA Sathish, SM Bishop, ...
Biochemistry 52 (19), 3376-3389, 2013
1402013
Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass …
P Manikwar, R Majumdar, JM Hickey, SV Thakkar, HS Samra, HA Sathish, ...
Journal of pharmaceutical sciences 102 (7), 2136-2151, 2013
1132013
Analytical lessons learned from selected therapeutic protein drug comparability studies
M Federici, A Lubiniecki, P Manikwar, DB Volkin
Biologicals 41 (3), 131-147, 2013
902013
Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, J Arora, CR Middaugh, DB Volkin, ...
Journal of the American Society for Mass Spectrometry 23 (12), 2140-2148, 2012
902012
cIBR effectively targets nanoparticles to LFA-1 on acute lymphoblastic T cells
C Chittasupho, P Manikwar, JP Krise, TJ Siahaan, C Berkland
Molecular pharmaceutics 7 (1), 146-155, 2010
492010
Antigen‐specific blocking of CD4‐specific immunological synapse formation using BPI and current therapies for autoimmune diseases
P Manikwar, P Kiptoo, AH Badawi, B Büyüktimkin, TJ Siahaan
Medicinal research reviews 32 (4), 727-764, 2012
432012
Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions
PS Sarangapani, J Weaver, A Parupudi, TMD Besong, GG Adams, ...
Journal of pharmaceutical sciences 105 (12), 3496-3506, 2016
292016
Characterization of a novel bispecific antibody with improved conformational and chemical stability
P Manikwar, SHR Mulagapati, S Kasturirangan, K Moez, GJ Rainey, ...
Journal of Pharmaceutical Sciences 109 (1), 220-232, 2020
222020
Utilization of I-domain of LFA-1 to target drug and marker molecules to leukocytes
P Manikwar, BA Tejo, H Shinogle, DS Moore, T Zimmerman, F Blanco, ...
Theranostics 1, 277, 2011
202011
Mechanism of a decrease in potency for the recombinant influenza A virus hemagglutinin H3 antigen during storage
JM Hickey, KM Holtz, P Manikwar, SB Joshi, CE Mcpherson, B Buckland, ...
Journal of pharmaceutical sciences 103 (3), 821-827, 2014
192014
Rapid identification of fluorochrome modification sites in proteins by LC ESI-Q-TOF mass spectrometry
P Manikwar, T Zimmerman, FJ Blanco, TD Williams, TJ Siahaan
Bioconjugate chemistry 22 (7), 1330-1336, 2011
192011
Bispecific binding proteins and uses thereof
S Kasturirangan, C Gao, G RAINEY, M Morrow, CL Dobson, S Drabic, ...
US Patent 10,457,732, 2019
122019
I-domain-antigen conjugate (IDAC) for delivering antigenic peptides to APC: synthesis, characterization, and in vivo EAE suppression
P Manikwar, B Büyüktimkin, P Kiptoo, AH Badawi, NA Galeva, ...
Bioconjugate chemistry 23 (3), 509-517, 2012
122012
Spray drying process challenges and considerations for inhaled biologics
S Poozesh, P Connaughton, S Sides, D Lechuga-Ballesteros, SM Patel, ...
Journal of Pharmaceutical Sciences 114 (2), 766-781, 2025
82025
Vaccinelike and prophylactic treatments of EAE with novel I-domain antigen conjugates (IDAC): targeting multiple antigenic peptides to APC
B Büyüktimkin, P Manikwar, PK Kiptoo, AH Badawi, JM Stewart Jr, ...
Molecular pharmaceutics 10 (1), 297-306, 2013
82013
Rapid room-temperature aerosol dehydration versus spray drying: A novel paradigm in biopharmaceutical drying technologies
S Poozesh, M Mezhericher, Z Pan, U Chaudhary, P Manikwar, HA Stone
Journal of Pharmaceutical Sciences 113 (4), 974-981, 2024
52024
Sensitivity and uncertainty analysis of micro-flow imaging for sub-visible particle measurements using artificial neural network
S Poozesh, F Cannavò, P Manikwar
Pharmaceutical Research 40 (3), 721-733, 2023
52023
Preformulation characterization, stabilization, and formulation design for the acrylodan-labeled glucose-binding protein SM4-AC
N Sahni, R Chaudhuri, JM Hickey, P Manikwar, A D’Souza, A Metters, ...
Journal of Pharmaceutical Sciences 106 (5), 1197-1210, 2017
52017
Bispecific binding proteins and uses thereof
S Kasturirangan, C Gao, G RAINEY, M Morrow, CL Dobson, S Drabic, ...
US Patent 11,279,759, 2022
32022
Dry powder formulations of thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of use thereof
CEC HUNTINGTON, HOE Susan, P Manikwar, RW KOLBECK, ES Cohen, ...
US Patent 11,904,053, 2024
12024
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