| Applications of machine learning to diagnosis and treatment of neurodegenerative diseases MA Myszczynska, PN Ojamies, AMB Lacoste, D Neil, A Saffari, R Mead, ... Nature reviews neurology 16 (8), 440-456, 2020 | 726 | 2020 |
| A simple method for improving protein solubility and long-term stability AP Golovanov, GM Hautbergue, SA Wilson, LY Lian Journal of the American Chemical Society 126 (29), 8933-8939, 2004 | 645 | 2004 |
| The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ... The EMBO journal 35 (15), 1656-1676, 2016 | 540 | 2016 |
| Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions J Cooper-Knock, MJ Walsh, A Higginbottom, J Robin Highley, ... Brain 137 (7), 2040-2051, 2014 | 411 | 2014 |
| Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8 Y Hargous, GM Hautbergue, AM Tintaru, L Skrisovska, AP Golovanov, ... The EMBO journal 25 (21), 5126, 2006 | 259 | 2006 |
| TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export N Viphakone, GM Hautbergue, M Walsh, CT Chang, A Holland, EG Folco, ... Nature communications 3 (1), 1006, 2012 | 256 | 2012 |
| C9ORF72 GGGGCC expanded repeats produce splicing dysregulation which correlates with disease severity in amyotrophic lateral sclerosis J Cooper-Knock, JJ Bury, PR Heath, M Wyles, A Higginbottom, ... PloS one 10 (5), e0127376, 2015 | 245 | 2015 |
| Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP GM Hautbergue, ML Hung, AP Golovanov, LY Lian, SA Wilson Proceedings of the National Academy of Sciences 105 (13), 5154-5159, 2008 | 243 | 2008 |
| Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS A Varcianna, MA Myszczynska, LM Castelli, B O'Neill, Y Kim, J Talbot, ... EBioMedicine 40, 626-635, 2019 | 236 | 2019 |
| Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy J Cooper-Knock, A Higginbottom, MJ Stopford, JR Highley, PG Ince, ... Acta neuropathologica 130 (1), 63-75, 2015 | 229 | 2015 |
| C9orf72 expansion disrupts ATM-mediated chromosomal break repair C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ... Nature neuroscience 20 (9), 1225-1235, 2017 | 220 | 2017 |
| Ribosome-inactivating proteins: Potent poisons and molecular tools MJ Walsh, JE Dodd, GM Hautbergue Virulence 4 (8), 774-784, 2013 | 189 | 2013 |
| UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA GM Hautbergue, ML Hung, MJ Walsh, APL Snijders, CT Chang, R Jones, ... Current Biology 19 (22), 1918-1924, 2009 | 175 | 2009 |
| SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ... Nature communications 8 (1), 16063, 2017 | 169 | 2017 |
| Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs P Knuckles, MA Vogt, S Lugert, M Milo, MMW Chong, GM Hautbergue, ... Nature neuroscience 15 (7), 962-969, 2012 | 151 | 2012 |
| Chtop is a component of the dynamic TREX mRNA export complex CT Chang, GM Hautbergue, MJ Walsh, N Viphakone, TB Van Dijk, ... The EMBO journal 32 (3), 473-486, 2013 | 149 | 2013 |
| Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis SP Allen, B Hall, LM Castelli, L Francis, R Woof, AP Siskos, E Kouloura, ... Brain 142 (3), 586-605, 2019 | 135 | 2019 |
| A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A A Cruz-Migoni, GM Hautbergue, PJ Artymiuk, PJ Baker, M Bokori-Brown, ... Science 334 (6057), 821-824, 2011 | 135 | 2011 |
| Structural and functional analysis of RNA and TAP binding to SF2/ASF AM Tintaru, GM Hautbergue, AM Hounslow, ML Hung, LY Lian, ... EMBO reports 8 (8), 756, 2007 | 106 | 2007 |
| The prototype γ-2 herpesvirus nucleocytoplasmic shuttling protein, ORF 57, transports viral RNA through the cellular mRNA export pathway BJL Williams, JR Boyne, DJ Goodwin, L Roaden, GM Hautbergue, ... Biochemical Journal 387 (2), 295-308, 2005 | 93 | 2005 |
Pamela J ShawProfessor of Neurology, University of SheffieldVerified email at sheffield.ac.uk
