| MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosis Y Yang, L Ding, Q Hu, J Xia, J Sun, X Wang, H Xiong, D Gurbani, L Li, ... Molecular cancer 16 (1), 141, 2017 | 150 | 2017 |
| PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response C Kim, XD Wang, Y Yu Elife 9, e60637, 2020 | 140 | 2020 |
| mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1 JJ Jia, RM Lahr, MT Solgaard, BJ Moraes, R Pointet, AD Yang, G Celucci, ... Nucleic Acids Research, 2021 | 118 | 2021 |
| TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation XD Wang, Y Gong, ZL Chen, BN Gong, JJ Xie, CQ Zhong, QL Wang, ... Nature immunology 16 (11), 1195-1203, 2015 | 66 | 2015 |
| Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells XD Wang, R Hu, Q Ding, TK Savage, KE Huffman, N Williams, MH Cobb, ... Nature communications 10 (1), 3201, 2019 | 49 | 2019 |
| Nimbolide targets RNF114 to induce the trapping of PARP1 and synthetic lethality in BRCA-mutated cancer P Li, Y Zhen, C Kim, Z Liu, J Hao, H Deng, H Deng, M Zhou, XD Wang, ... Science advances 9 (43), eadg7752, 2023 | 40 | 2023 |
| The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5 X Liu, W Xiao, XD Wang, YF Li, J Han, Y Li Journal of Biological Chemistry 288 (51), 36648-36661, 2013 | 32 | 2013 |
| Targeting scaffolding functions of enzymes using PROTAC approaches C Kim, XD Wang, Z Liu, S Zha, Y Yu Biochemistry 62 (3), 561-563, 2022 | 25 | 2022 |
| Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification Z Zi, Z Zhang, Q Feng, C Kim, XD Wang, PE Scherer, J Gao, B Levine, ... Nature communications 13 (1), 1760, 2022 | 24 | 2022 |
| A novel miR-200b-3p/p38IP pair regulates monocyte/macrophage differentiation X Yu, QL Wang, YF Li, XD Wang, A Xu, Y Li Cell discovery 2 (1), 1-15, 2016 | 23 | 2016 |
| Synthesis of nimbolide and its analogues and their application as poly (ADP-ribose) polymerase-1 trapping inducers H Deng, H Deng, C Kim, P Li, X Wang, Y Yu, T Qin Nature synthesis 3 (3), 378-385, 2024 | 18 | 2024 |
| LARP1 is a major phosphorylation substrate of mTORC1 BD Fonseca, JJ Jia, AK Hollensen, R Pointet, HD Hoang, MR Niklaus, ... BioRxiv, 491274, 2018 | 17 | 2018 |
| The p38‐interacting protein p38IP suppresses TCR and LPS signaling by targeting TAK1 XD Wang, CS Zhao, QL Wang, Q Zeng, XZ Feng, L Li, ZL Chen, Y Gong, ... EMBO reports, e48035, 2020 | 14 | 2020 |
| Cholesterol regulates the tumor adaptive resistance to MAPK pathway inhibition XD Wang, C Kim, Y Zhang, S Rindhe, MH Cobb, Y Yu Journal of proteome research 20 (12), 5379-5391, 2021 | 12 | 2021 |
| PARP1 inhibitors induce pyroptosis via caspase 3-mediated gasdermin E cleavage C Kim, XD Wang, S Jang, Y Yu Biochemical and biophysical research communications 646, 78-85, 2023 | 9 | 2023 |
| Impact of Asp/Glu‐ADP‐ribosylation on protein‐protein interaction and protein function J Pei, J Zhang, XD Wang, C Kim, Y Yu, Q Cong Proteomics 23 (17), 2200083, 2023 | 8 | 2023 |
| Machine learning for cancer subtype prediction with fsa method Y Liu, XD Wang, M Qiu, H Zhao International Conference on Smart Computing and Communication, 387-397, 2019 | 8 | 2019 |
| Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors C Kim, XD Wang, Z Liu, J Hao, S Wang, P Li, Z Zi, Q Ding, S Jang, J Kim, ... Science Advances 10 (3), eadh2579, 2024 | 6 | 2024 |
| Biomimetic electrodeposition of hydroxyapatite onto TiO2 nanotubes modified by L-aspartic acid W Zhang, C Lu, S Huang, X Wang, Z Zhu, X Huang, Y Zeng 2007 1st International Conference on Bioinformatics and Biomedical …, 2007 | 3 | 2007 |
| Nimbolide targets RNF114 to induce the trapping of PARP1 and poly-ADP-ribosylation-dependent DNA repair factors P Li, Y Zhen, C Kim, H Deng, H Deng, XD Wang, T Qin, Y Yu bioRxiv, 2022.10. 04.510815, 2022 | 2 | 2022 |
Yonghao YuProfessor of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical CenterVerified email at cumc.columbia.edu
