| Cancer stem cells CT Jordan, ML Guzman, M Noble New England Journal of Medicine 355 (12), 1253-1261, 2006 | 2197 | 2006 |
| BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells ED Lagadinou, A Sach, K Callahan, RM Rossi, SJ Neering, ... Cell stem cell 12 (3), 329-341, 2013 | 1516 | 2013 |
| Functional genomic landscape of acute myeloid leukaemia JW Tyner, CE Tognon, D Bottomly, B Wilmot, SE Kurtz, SL Savage, ... Nature 562 (7728), 526-531, 2018 | 1439 | 2018 |
| The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells CT Jordan, D Upchurch, SJ Szilvassy, ML Guzman, DS Howard, ... Leukemia 14 (10), 1777-1784, 2000 | 1106 | 2000 |
| Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells ML Guzman, SJ Neering, D Upchurch, B Grimes, DS Howard, DA Rizzieri, ... Blood 98 (8), 2301-2307, 2001 | 1044 | 2001 |
| The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells ML Guzman, RM Rossi, L Karnischky, X Li, DR Peterson, DS Howard, ... Blood 105 (11), 4163-4169, 2005 | 933 | 2005 |
| The increasing complexity of the cancer stem cell paradigm JM Rosen, CT Jordan science 324 (5935), 1670-1673, 2009 | 918 | 2009 |
| A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations W Matthews, CT Jordan, GW Wiegand, D Pardoll, IR Lemischka Cell 65 (7), 1143-1152, 1991 | 830 | 1991 |
| Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia DA Pollyea, BM Stevens, CL Jones, A Winters, S Pei, M Minhajuddin, ... Nature medicine 24 (12), 1859-1866, 2018 | 781 | 2018 |
| Clonal and systemic analysis of long-term hematopoiesis in the mouse. CT Jordan, IR Lemischka Genes & development 4 (2), 220-232, 1990 | 745 | 1990 |
| A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. W Matthews, CT Jordan, M Gavin, NA Jenkins, NG Copeland, ... Proceedings of the National Academy of Sciences 88 (20), 9026-9030, 1991 | 697 | 1991 |
| Preferential induction of apoptosis for primary human leukemic stem cells ML Guzman, CF Swiderski, DS Howard, BA Grimes, RM Rossi, ... Proceedings of the National Academy of Sciences 99 (25), 16220-16225, 2002 | 645 | 2002 |
| Inhibition of amino acid metabolism selectively targets human leukemia stem cells CL Jones, BM Stevens, A D'Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ... Cancer cell 34 (5), 724-740. e4, 2018 | 610 | 2018 |
| Leukemic stem cells evade chemotherapy by metabolic adaptation to an adipose tissue niche H Ye, B Adane, N Khan, T Sullivan, M Minhajuddin, M Gasparetto, ... Cell stem cell 19 (1), 23-37, 2016 | 604 | 2016 |
| Acute myeloid leukaemia A Khwaja, M Bjorkholm, RE Gale, RL Levine, CT Jordan, G Ehninger, ... Nature reviews Disease primers 2 (1), 1-22, 2016 | 569 | 2016 |
| Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics GB Koo, MJ Morgan, DG Lee, WJ Kim, JH Yoon, JS Koo, SI Kim, SJ Kim, ... Cell research 25 (6), 707-725, 2015 | 550 | 2015 |
| An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells ML Guzman, RM Rossi, S Neelakantan, X Li, CA Corbett, DC Hassane, ... Blood, The Journal of the American Society of Hematology 110 (13), 4427-4435, 2007 | 550 | 2007 |
| Monocytic subclones confer resistance to venetoclax-based therapy in patients with acute myeloid leukemia S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ... Cancer discovery 10 (4), 536-551, 2020 | 538 | 2020 |
| Stable transduction of quiescent CD34+CD38− human hematopoietic cells by HIV-1-based lentiviral vectors SS Case, MA Price, CT Jordan, XJ Yu, L Wang, G Bauer, DL Haas, D Xu, ... Proceedings of the National Academy of Sciences 96 (6), 2988-2993, 1999 | 517 | 1999 |
| Leukemia stem cells and microenvironment: biology and therapeutic targeting MY Konopleva, CT Jordan Journal of clinical oncology 29 (5), 591-599, 2011 | 503 | 2011 |
