| Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis EI Tucker, NG Verbout, PY Leung, S Hurst, OJT McCarty, D Gailani, ... Blood, The Journal of the American Society of Hematology 119 (20), 4762-4768, 2012 | 127 | 2012 |
| The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial CU Lorentz, EI Tucker, NG Verbout, JJ Shatzel, SR Olson, BD Markway, ... Blood, The Journal of the American Society of Hematology 138 (22), 2173-2184, 2021 | 120 | 2021 |
| Contact activation inhibitor and factor XI antibody, AB023, produces safe, dose-dependent anticoagulation in a phase 1 first-in-human trial CU Lorentz, NG Verbout, M Wallisch, MW Hagen, JJ Shatzel, SR Olson, ... Arteriosclerosis, thrombosis, and vascular biology 39 (4), 799-809, 2019 | 101 | 2019 |
| Inhibition of factor XII-mediated activation of factor XI provides protection against experimental acute ischemic stroke in mice PY Leung, S Hurst, MA Berny-Lang, NG Verbout, D Gailani, EI Tucker, ... Translational stroke research 3 (3), 381-389, 2012 | 73 | 2012 |
| The safety and efficacy of novel agents targeting factors XI and XII in early phase human trials EP DeLoughery, SR Olson, C Puy, OJT McCarty, JJ Shatzel Seminars in thrombosis and hemostasis 45 (05), 502-508, 2019 | 70 | 2019 |
| Pulmonary inflammation induced by subacute ozone is augmented in adiponectin-deficient mice: role of IL-17A DI Kasahara, HY Kim, AS Williams, NG Verbout, J Tran, H Si, ... The Journal of Immunology 188 (9), 4558-4567, 2012 | 69 | 2012 |
| Role of the adiponectin binding protein, T-cadherin (Cdh13), in allergic airways responses in mice AS Williams, DI Kasahara, NG Verbout, AV Fedulov, M Zhu, H Si, ... PLoS One 7 (7), e41088, 2012 | 54 | 2012 |
| Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice M Zhu, C Hug, DI Kasahara, RA Johnston, AS Williams, NG Verbout, H Si, ... American journal of respiratory cell and molecular biology 43 (4), 487-497, 2010 | 53 | 2010 |
| Pulmonary responses to subacute ozone exposure in obese vs. lean mice SA Shore, JE Lang, DI Kasahara, FL Lu, NG Verbout, H Si, ES Williams, ... Journal of applied physiology 107 (5), 1445-1452, 2009 | 50 | 2009 |
| Role of Rho kinase isoforms in murine allergic airway responses M Zhu, PY Liu, DI Kasahara, AS Williams, NG Verbout, AJ Halayko, ... European Respiratory Journal 38 (4), 841-850, 2011 | 47 | 2011 |
| Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes A Itakura, NG Verbout, KG Phillips, RH Insall, D Gailani, EI Tucker, ... Journal of leukocyte biology 90 (5), 923-927, 2011 | 41 | 2011 |
| Atropine pretreatment enhances airway hyperreactivity in antigen-challenged guinea pigs through an eosinophil-dependent mechanism NG Verbout, JK Lorton, DB Jacoby, AD Fryer American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (5 …, 2007 | 39 | 2007 |
| Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice DI Kasahara, HY Kim, JA Mathews, NG Verbout, AS Williams, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 306 (6 …, 2014 | 33 | 2014 |
| Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis NG Verbout, X Yu, LD Healy, KG Phillips, EI Tucker, A Gruber, ... Metabolic brain disease 30 (1), 57-65, 2015 | 29 | 2015 |
| Impact of adiponectin overexpression on allergic airways responses in mice NG Verbout, L Benedito, AS Williams, DI Kasahara, AP Wurmbrand, H Si, ... Journal of Allergy 2013 (1), 349520, 2013 | 29 | 2013 |
| Atropine-enhanced, antigen challenge-induced airway hyperreactivity in guinea pigs is mediated by eosinophils and nerve growth factor NG Verbout, DB Jacoby, GJ Gleich, AD Fryer American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (2 …, 2009 | 28 | 2009 |
| Single low dose of rFVIIa combined with antifibrinolytic agent is a simple and safe treatment for factor XI-deficient patients undergoing surgery O Salomon, I Budnik, E Avishai, I Tamarin, D Bashari, R Dardik, T Livnat Thrombosis and Haemostasis 119 (12), 1927-1932, 2019 | 20 | 2019 |
| Impact of deficiency of intrinsic coagulation factors XI and XII on ex vivo thrombus formation and clot lysis JWP Govers-Riemslag, J Konings, JMEM Cosemans, JP van Geffen, ... TH Open 3 (03), e273-e285, 2019 | 16 | 2019 |
| Factor XI contributes to myocardial ischemia-reperfusion injury in mice CU Lorentz, NG Verbout, Z Cao, L Liu, MT Hinds, OJT McCarty, I Ivanov, ... Blood advances 2 (2), 85-88, 2018 | 16 | 2018 |
| Thrombin generation and activity in multiple sclerosis KR Jordan, I Parra-Izquierdo, A Gruber, JJ Shatzel, P Pham, LS Sherman, ... Metabolic brain disease 36 (3), 407-420, 2021 | 14 | 2021 |
