| A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division M Amaral, FS de Sousa, TAC Silva, AJG Junior, NN Taniwaki, DM Johns, ... Scientific Reports 9 (1), 6114, 2019 | 35 | 2019 |
| Enantioselective synthesis and anti-parasitic properties of aporphine natural products P Pieper, E McHugh, M Amaral, AG Tempone, EA Anderson Tetrahedron 76 (2), 130814, 2020 | 32 | 2020 |
| (-)-T-Cadinol—a Sesquiterpene Isolated From Casearia sylvestris (Salicaceae)—Displayed In Vitro Activity and Causes Hyperpolarization of the Membrane Potential of Trypanosoma … AL Dos Santos, M Amaral, FR Hasegawa, JHG Lago, AG Tempone, ... Frontiers in Pharmacology 12, 734127, 2021 | 31 | 2021 |
| Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria GAA Conserva, TA da Costa-Silva, M Amaral, GM Antar, BJ Neves, ... Phytomedicine 54, 302-307, 2019 | 24 | 2019 |
| Mitochondrial Imbalance of Trypanosoma cruzi Induced by the Marine Alkaloid 6-Bromo-2′-de-N-Methylaplysinopsin MM Romanelli, M Amaral, F Thevenard, LM Santa Cruz, LO Regasini, ... ACS omega 7 (32), 28561-28570, 2022 | 21 | 2022 |
| Dereplication of Aporphine Alkaloids by UHPLC-HR-ESI-MS/MS and NMR from Duguetia lanceolata St. -Hil (Annonaceae) and Antiparasitic Activity Evaluation EP Dantas, J Monteiro, LS Medeiros, MM Romanelli, M Amaral, ... Journal of the Brazilian Chemical Society 31 (9), 1908-1916, 2020 | 16 | 2020 |
| Aporphine Alkaloids from Ocotea puberula with Anti‐Trypanosoma Cruzi Potential – Activity of Dicentrine‐β‐N‐Oxide in the Plasma Membrane Electric Potentials H Barbosa, TA Costa‐Silva, GA Alves Conserva, AJ Araujo, ALL Lordello, ... Chemistry & Biodiversity 18 (4), e2001022, 2021 | 15 | 2021 |
| Synthesis and Structure–Activity Relationship of Dehydrodieugenol B Neolignans against Trypanosoma cruzi CE Sear, P Pieper, M Amaral, MM Romanelli, TA Costa-Silva, ... ACS Infectious Diseases 6 (11), 2872-2878, 2020 | 13 | 2020 |
| Hedyosulide, a novel trypanosomicidal sesterterpene lactone from Hedyosmum brasiliense Mart. ex Miq C Murakami, RSA Cabral, KS Gomes, TA Costa-Silva, M Amaral, ... Phytochemistry Letters 33, 6-11, 2019 | 11 | 2019 |
| Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi MT Varela, M Amaral, MM Romanelli, EV Levatti, AG Tempone, ... European Journal of Pharmaceutical Sciences, 2022 | 9 | 2022 |
| Andrographolide: A Diterpenoid from Cymbopogon schoenanthus Identified as a New Hit Compound against Trypanosoma cruzi Using Machine Learning and … H Barbosa, GZ Espinoza, M Amaral, EV de Castro Levatti, MB Abiuzi, ... Journal of Chemical Information and Modeling 64 (7), 2565-2576, 2023 | 7 | 2023 |
| Piperazine amides with desirable solubility, physicochemical and drug-like properties: Synthesis and evaluation of the anti-Trypanosoma cruzi activity MT Varela, M Romanelli, M Amaral, AG Tempone, JPS Fernandes Saudi Pharmaceutical Journal 31 (7), 1265-1273, 2023 | 7 | 2023 |
| Evaluation of antileishmanial potential of the antidepressant escitalopram in Leishmania infantum ML Lima, M Amaral, AG Tempone Journal of Pharmaceutical and Biomedical Analysis 209, 114469, 2022 | 7 | 2022 |
| A new reduced chalcone-derivative affects the membrane permeability and electric potential of multidrug-resistant Enterococcus faecalis AG Tempone, R dos Santos Theodoro, MM Romanelli, DAS Ferreira, ... Chemico-Biological Interactions 365, 110086, 2022 | 5 | 2022 |
| γ‐Lactones from Persea americana and Persea fulva – in Vitro and in Silico Evaluation of Trypanosoma cruzi Activity IMA Reis, E Umehara, RS Conceição, L de M. Oliveira, ... Chemistry & Biodiversity 18 (9), e2100362, 2021 | 5 | 2021 |
| Synthesis of a dehydrodieugenol B derivative as a lead compound for visceral leishmaniasis—mechanism of action and in vivo pharmacokinetic studies M Amaral, MM Romanelli, H Asiki, J Bicker, DP Lage, CS Freitas, ... Antimicrobial Agents and Chemotherapy 68 (11), e00831-24, 2024 | 3 | 2024 |
| Biological activity and structure–activity relationship of dehydrodieugenol B analogues against visceral leishmaniasis M Amaral, H Asiki, CE Sear, S Singh, P Pieper, MM Haugland, ... RSC Medicinal Chemistry 14 (7), 1344-1350, 2023 | 3 | 2023 |
| Synthesis and evaluation of (Bis) benzyltetrahydroisoquinoline alkaloids as antiparasitic agents A Sozanschi, H Asiki, M Amaral, EV de Castro Levatti, AG Tempone, ... Jacs Au 4 (2), 847-854, 2024 | 2 | 2024 |
| Características físicas e químicas de solos ocupados com pinheiro-manso ME Marcelo, I Carrasquinho, P Jordão, R Mano, F Calouro, M Gaspar, ... Revista Rural 2020, 24-27, 2020 | 2 | 2020 |
| Effect of the Alkyl Side Chain of Antitrypanosomal Cinnamate, p-Coumarate, and Ferulate n-Alkyl Esters Using Multivariate Analysis and Computer-Aided Drug … ML Silva, JL Baldim, TA Costa-Silva, M Amaral, MM Romanelli, ... Journal of the Brazilian Chemical Society 36 (8), e-20240203, 2024 | 1 | 2024 |