| Mutational landscape of secondary glioblastoma guides MET-targeted trial in brain tumor H Hu, Q Mu, Z Bao, Y Chen, Y Liu, J Chen, K Wang, Z Wang, Y Nam, ... Cell 175 (6), 1665-1678. e18, 2018 | 343 | 2018 |
| Inosine induces stemness features in CAR-T cells and enhances potency DD Klysz, C Fowler, M Malipatlolla, L Stuani, KA Freitas, Y Chen, S Meier, ... Cancer Cell 42 (2), 266-282. e8, 2024 | 124 | 2024 |
| Engineered CD47 protects T cells for enhanced antitumour immunity SA Yamada-Hunter, J Theruvath, BJ McIntosh, KA Freitas, F Lin, ... Nature 630 (8016), 457-465, 2024 | 96 | 2024 |
| Somatic MAP3K3 mutation defines a subclass of cerebral cavernous malformation J Weng, Y Yang, D Song, R Huo, H Li, Y Chen, Y Nam, Q Zhou, Y Jiao, ... The American Journal of Human Genetics 108 (5), 942-950, 2021 | 96 | 2021 |
| Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells B Laffleur, J Lim, W Zhang, Y Chen, E Pefanis, J Bizarro, CR Batista, L Wu, ... Nature genetics 53 (2), 230-242, 2021 | 80 | 2021 |
| Deciphering brain complexity using single-cell sequencing Q Mu, Y Chen, J Wang Genomics, proteomics & bioinformatics 17 (4), 344-366, 2019 | 75 | 2019 |
| GLUT1 overexpression in CAR-T cells induces metabolic reprogramming and enhances potency JA Guerrero, DD Klysz, Y Chen, M Malipatlolla, J Lone, C Fowler, L Stuani, ... Nature Communications 15 (1), 8658, 2024 | 66 | 2024 |
| Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination G Rothschild, W Zhang, J Lim, PK Giri, B Laffleur, Y Chen, M Fang, ... Science immunology 5 (44), eaay5864, 2020 | 48 | 2020 |
| Tumor-associated monocytes promote mesenchymal transformation through EGFR signaling in glioma Y Chen, R Huo, W Kang, Y Liu, Z Zhao, W Fu, R Ma, X Zhang, J Tang, ... Cell Reports Medicine 4 (9), 2023 | 45 | 2023 |
| Ca2+-induced rigidity change of the myosin VIIa IQ motif-single α helix lever arm extension J Li, Y Chen, Y Deng, IC Unarta, Q Lu, X Huang, M Zhang Structure 25 (4), 579-591. e4, 2017 | 42 | 2017 |
| Classifying gastric cancer using FLORA reveals clinically relevant molecular subtypes and highlights LINC01614 as a biomarker for patient prognosis Y Chen, WY Cheng, H Shi, S Huang, H Chen, D Liu, W Xu, J Yu, J Wang Oncogene 40 (16), 2898-2909, 2021 | 37 | 2021 |
| Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression RJ Leeman-Neill, D Song, J Bizarro, L Wacheul, G Rothschild, S Singh, ... Nature genetics 55 (12), 2160-2174, 2023 | 34 | 2023 |
| Structural basis for the high-affinity interaction between CASK and Mint1 X Wu, Q Cai, Y Chen, S Zhu, J Mi, J Wang, M Zhang Structure 28 (6), 664-673. e3, 2020 | 23 | 2020 |
| Inhibition of SOCE disrupts cytokinesis in zebrafish embryos via inhibition of cleavage furrow deepening. CM Chan, Y Chen, TS Hung, AL Miller, AM Shipley, SE Webb The International journal of developmental biology 59 (7-9), 289-301, 2015 | 20 | 2015 |
| Tumor-associated microglia secrete extracellular ATP to support glioblastoma progression CYJ Wu, Y Chen, YJ Lin, KC Wei, KY Chang, LY Feng, KT Chen, G Li, ... Cancer Research 84 (23), 4017-4030, 2024 | 14 | 2024 |
| The CCR6–CCL20 Axis Promotes Regulatory T-cell Glycolysis and Immunosuppression in Tumors A Pant, A Jain, Y Chen, K Patel, L Saleh, S Tzeng, RT Nitta, L Zhao, ... Cancer immunology research 12 (11), 1542-1558, 2024 | 11 | 2024 |
| Immune signatures of GD2 CAR T cell activity in H3K27M+ diffuse midline glioma patients S Ramakrishna, Z Good, M Desai, D Zamler, R Mancusi, J Mahdi, ... Cancer Research 83 (7_Supplement), 959-959, 2023 | 4 | 2023 |
| Lineage tracing of CAR T cells in patients with B cell malignancies Z Good, MP Hamilton, JY Spiegel, S Kurra, MH Desai, S Prabhu, ... Cancer Research 83 (7_Supplement), 1128-1128, 2023 | 2 | 2023 |
| Combined silencing of MED12 and activation of IL2 by epigenetic editing enhances CAR T antitumor potency F Lin, S Yamada-Hunter, A Croft, N DeNamur, E Tokuda, M Libbrecht, ... Cancer Research 85 (8_Supplement_1), 3765-3765, 2025 | 1 | 2025 |
| CCL8/CCL13-producing tumor-associated macrophages linked to poor outcomes after CAR T cell therapy for LBCL KC Mo, CY Yeh, MP Hamilton, J Spiegel, M Desai, Z Ehlinger, ... Blood 144, 368, 2024 | 1 | 2024 |