| Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme C Jeronimo, D Forget, A Bouchard, Q Li, G Chua, C Poitras, C Thérien, ... Molecular cell 27 (2), 262-274, 2007 | 528 | 2007 |
| Binding of the 7SK snRNA turns the HEXIM1 protein into a P‐TEFb (CDK9/cyclin T) inhibitor AA Michels, A Fraldi, Q Li, TE Adamson, F Bonnet, VT Nguyen, ... The EMBO journal 23 (13), 2608-2619, 2004 | 357 | 2004 |
| Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated … Q Li, JP Price, SA Byers, D Cheng, J Peng, DH Price Journal of Biological Chemistry 280 (31), 28819-28826, 2005 | 265 | 2005 |
| SETD2 restricts prostate cancer metastasis by integrating EZH2 and AMPK signaling pathways H Yuan, Y Han, X Wang, N Li, Q Liu, Y Yin, H Wang, L Pan, L Li, K Song, ... Cancer cell 38 (3), 350-365. e7, 2020 | 193 | 2020 |
| Insulin‐like growth factor‐1 regulates the SIRT 1‐p53 pathway in cellular senescence D Tran, J Bergholz, H Zhang, H He, Y Wang, Y Zhang, Q Li, JL Kirkland, ... Aging cell 13 (4), 669-678, 2014 | 183 | 2014 |
| Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis H Yuan, NI Li, DA Fu, J Ren, J Hui, J Peng, Y Liu, T Qiu, M Jiang, Q Pan, ... The Journal of clinical investigation 127 (9), 3375-3391, 2017 | 169 | 2017 |
| HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK SA Byers, JP Price, JJ Cooper, Q Li, DH Price Journal of Biological Chemistry 280 (16), 16360-16367, 2005 | 143 | 2005 |
| Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer H Wang, N Li, Q Liu, J Guo, Q Pan, B Cheng, J Xu, B Dong, G Yang, ... Cancer Cell 41 (7), 1345-1362. e9, 2023 | 141 | 2023 |
| AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis N Li, W Xue, H Yuan, B Dong, Y Ding, Y Liu, M Jiang, S Kan, T Sun, J Ren, ... The Journal of clinical investigation 127 (4), 1284-1302, 2017 | 127 | 2017 |
| ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression N Li, Q Liu, Y Han, S Pei, B Cheng, J Xu, X Miao, Q Pan, H Wang, J Guo, ... Nature communications 13 (1), 7281, 2022 | 89 | 2022 |
| Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer Y Ding, N Li, B Dong, W Guo, H Wei, Q Chen, H Yuan, Y Han, H Chang, ... The Journal of clinical investigation 129 (2), 759-773, 2019 | 88 | 2019 |
| Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations T Yang, J Zhang, D Ke, W Yang, M Tang, J Jiang, G Cheng, J Li, W Cheng, ... Nature communications 10 (1), 3214, 2019 | 84 | 2019 |
| Nucleophosmin interacts with HEXIM1 and regulates RNA polymerase II transcription M Gurumurthy, CH Tan, R Ng, L Zeiger, J Lau, J Lee, A Dey, R Philp, Q Li, ... Journal of molecular biology 378 (2), 302-317, 2008 | 81 | 2008 |
| Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells Q Dai, T Lei, C Zhao, J Zhong, Y Tang, B Chen, J Yang, C Li, S Wang, ... Journal of Biological Chemistry 287 (30), 25344-25352, 2012 | 75 | 2012 |
| Histone methyltransferase WHSC1 loss dampens MHC-I antigen presentation pathway to impair IFN-γ–stimulated antitumor immunity J Ren, N Li, S Pei, Y Lian, L Li, Y Peng, Q Liu, J Guo, X Wang, Y Han, ... The Journal of Clinical Investigation 132 (8), 2022 | 72 | 2022 |
| Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation T Lei, P Zhang, X Zhang, X Xiao, J Zhang, T Qiu, Q Dai, Y Zhang, L Min, ... Nature communications 9 (1), 1876, 2018 | 65 | 2018 |
| PKC phosphorylates HEXIM1 and regulates P-TEFb activity K Fujinaga, M Barboric, Q Li, Z Luo, DH Price, BM Peterlin Nucleic acids research 40 (18), 9160-9170, 2012 | 60 | 2012 |
| Cyclin T2 is essential for mouse embryogenesis J Kohoutek, Q Li, D Blazek, Z Luo, H Jiang, BM Peterlin Molecular and cellular biology 29 (12), 3280-3285, 2009 | 60 | 2009 |
| HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells Q Li, JJ Cooper, GH Altwerger, MD Feldkamp, MA Shea, DH Price Nucleic acids research 35 (8), 2503-2512, 2007 | 60 | 2007 |
| The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability Q Pan, S Zhong, H Wang, X Wang, N Li, Y Li, G Zhang, H Yuan, Y Lian, ... Molecular Cell 81 (13), 2736-2751. e8, 2021 | 52 | 2021 |
