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Ran Zalk
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Year
Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
DC Andersson, MJ Betzenhauser, S Reiken, AC Meli, A Umanskaya, ...
Cell metabolism 14 (2), 196-207, 2011
5282011
Structure of a mammalian ryanodine receptor
R Zalk, OB Clarke, A Des Georges, RA Grassucci, S Reiken, F Mancia, ...
Nature 517 (7532), 44-49, 2015
5252015
Modulation of the ryanodine receptor and intracellular calcium
R Zalk, SE Lehnart, AR Marks
Annu. Rev. Biochem. 76 (1), 367-385, 2007
4642007
Structural basis for gating and activation of RyR1
A des Georges, OB Clarke, R Zalk, Q Yuan, KJ Condon, RA Grassucci, ...
Cell 167 (1), 145-157. e17, 2016
4422016
Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria
Z Ran, A Israelson, ES Garty, H Azoulay-Zohar, V Shoshan-Barmatz
Biochemical Journal 386 (1), 73-83, 2005
2802005
Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target
H Dridi, A Kushnir, R Zalk, Q Yuan, Z Melville, AR Marks
Nature Reviews Cardiology 17 (11), 732-747, 2020
2232020
Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer’s disease-like pathologies and cognitive deficits
A Lacampagne, X Liu, S Reiken, R Bussiere, AC Meli, I Lauritzen, ...
Acta neuropathologica 134 (5), 749-767, 2017
1952017
Subcellular localization of VDAC in mitochondria and ER in the cerebellum
V Shoshan-Barmatz, R Zalk, D Gincel, N Vardi
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1657 (2-3), 105-114, 2004
1362004
Structural basis for SARM1 inhibition and activation under energetic stress
M Sporny, J Guez-Haddad, T Khazma, A Yaron, M Dessau, Y Shkolnisky, ...
Elife 9, e62021, 2020
1332020
Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor
R Bussiere, A Lacampagne, S Reiken, X Liu, V Scheuerman, R Zalk, ...
Journal of Biological Chemistry 292 (24), 10153-10168, 2017
692017
Hyperuricemia and gout caused by missense mutation in d-lactate dehydrogenase
M Drabkin, Y Yogev, L Zeller, R Zarivach, R Zalk, D Halperin, O Wormser, ...
The Journal of clinical investigation 129 (12), 5163-5168, 2019
532019
Ca2+ release channels join the ‘resolution revolution’
R Zalk, AR Marks
Trends in biochemical sciences 42 (7), 543-555, 2017
512017
Structural basis for the intracellular regulation of ferritin degradation
F Hoelzgen, TTP Nguyen, E Klukin, M Boumaiza, AK Srivastava, EY Kim, ...
Nature Communications 15 (1), 3802, 2024
432024
Packaging of DNA origami in viral capsids
I Kopatz, R Zalk, Y Levi-Kalisman, E Zlotkin-Rivkin, GA Frank, S Kler
Nanoscale 11 (21), 10160-10166, 2019
392019
Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes
AJW Hartel, P Ong, I Schroeder, MH Giese, S Shekar, OB Clarke, R Zalk, ...
Proceedings of the National Academy of Sciences 115 (8), E1789-E1798, 2018
302018
Targeting the mitochondrial protein VDAC1 as a potential therapeutic strategy in ALS
A Shteinfer-Kuzmine, S Argueti-Ostrovsky, MF Leyton-Jaimes, U Anand, ...
International Journal of Molecular Sciences 23 (17), 9946, 2022
292022
ATP-binding sites in brain p97/VCP (valosin-containing protein), a multifunctional AAA ATPase
R Zalk, V Shoshan-Barmatz
Biochemical Journal 374 (2), 473-480, 2003
242003
SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis
SK Pandey, A Paul, A Shteinfer‐Kuzmine, R Zalk, U Bunz, ...
Molecular Oncology 15 (11), 3037-3061, 2021
232021
Folding of an intrinsically disordered iron-binding peptide in response to sedimentation revealed by cryo-EM
G Davidov, G Abelya, R Zalk, B Izbicki, S Shaibi, L Spektor, D Shagidov, ...
Journal of the American Chemical Society 142 (46), 19551-19557, 2020
202020
RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation
Q Yuan, H Dridi, OB Clarke, S Reiken, Z Melville, A Wronska, A Kushnir, ...
Acta neuropathologica communications 9 (1), 186, 2021
162021
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Articles 1–20