| T-cell invigoration to tumour burden ratio associated with anti-PD-1 response AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ... Nature 545 (7652), 60-65, 2017 | 1782 | 2017 |
| TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion O Khan, JR Giles, S McDonald, S Manne, SF Ngiow, KP Patel, MT Werner, ... Nature 571 (7764), 211-218, 2019 | 1663 | 2019 |
| Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ... Science 369 (6508), eabc8511, 2020 | 1658 | 2020 |
| Developmental relationships of four exhausted CD8+ T cell subsets reveals underlying transcriptional and epigenetic landscape control mechanisms JC Beltra, S Manne, MS Abdel-Hakeem, M Kurachi, JR Giles, Z Chen, ... Immunity 52 (5), 825-841. e8, 2020 | 1072 | 2020 |
| mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern RR Goel, MM Painter, SA Apostolidis, D Mathew, W Meng, AM Rosenfeld, ... Science 374 (6572), abm0829, 2021 | 1002 | 2021 |
| Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination RR Goel, SA Apostolidis, MM Painter, D Mathew, A Pattekar, O Kuthuru, ... Science immunology 6 (58), eabi6950, 2021 | 803 | 2021 |
| TCF-1-centered transcriptional network drives an effector versus exhausted CD8 T cell-fate decision Z Chen, Z Ji, SF Ngiow, S Manne, Z Cai, AC Huang, J Johnson, ... Immunity 51 (5), 840-855. e5, 2019 | 747 | 2019 |
| CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer EM Bange, NA Han, P Wileyto, JY Kim, S Gouma, J Robinson, ... Nature medicine 27 (7), 1280-1289, 2021 | 543 | 2021 |
| Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination MM Painter, D Mathew, RR Goel, SA Apostolidis, A Pattekar, O Kuthuru, ... Immunity 54 (9), 2133-2142. e3, 2021 | 523 | 2021 |
| CD8+ T cells in the cancer-immunity cycle JR Giles, AM Globig, SM Kaech, EJ Wherry Immunity 56 (10), 2231-2253, 2023 | 344 | 2023 |
| Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation MS Abdel-Hakeem, S Manne, JC Beltra, E Stelekati, Z Chen, K Nzingha, ... Nature immunology 22 (8), 1008-1019, 2021 | 251 | 2021 |
| Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 LA Vella, JR Giles, AE Baxter, DA Oldridge, C Diorio, L Kuri-Cervantes, ... Science immunology 6 (57), eabf7570, 2021 | 246 | 2021 |
| Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics JR Giles, SF Ngiow, S Manne, AE Baxter, O Khan, P Wang, R Staupe, ... Nature immunology 23 (11), 1600-1613, 2022 | 227 | 2022 |
| Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine RR Goel, MM Painter, KA Lundgreen, SA Apostolidis, AE Baxter, JR Giles, ... Cell 185 (11), 1875-1887. e8, 2022 | 225 | 2022 |
| In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer Z Chen, E Arai, O Khan, Z Zhang, SF Ngiow, Y He, H Huang, S Manne, ... Cell 184 (5), 1262-1280. e22, 2021 | 205 | 2021 |
| Divergent clonal differentiation trajectories of T cell exhaustion B Daniel, KE Yost, S Hsiung, K Sandor, Y Xia, Y Qi, KJ Hiam-Galvez, ... Nature immunology 23 (11), 1614-1627, 2022 | 190 | 2022 |
| Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue M Buggert, S Nguyen, G Salgado-Montes de Oca, B Bengsch, S Darko, ... Science immunology 3 (24), eaar4526, 2018 | 184 | 2018 |
| Combined JAK inhibition and PD-1 immunotherapy for non–small cell lung cancer patients D Mathew, ME Marmarelis, C Foley, JM Bauml, D Ye, R Ghinnagow, ... Science 384 (6702), eadf1329, 2024 | 169 | 2024 |
| T follicular helper cells in human efferent lymph retain lymphoid characteristics LA Vella, M Buggert, S Manne, RS Herati, I Sayin, L Kuri-Cervantes, ... The Journal of clinical investigation 129 (8), 3185-3200, 2019 | 165 | 2019 |
| UPenn COVID Processing Unit Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ... Science 369 (10.1126), 2020 | 129 | 2020 |