| The C9orf72 repeat expansion disrupts nucleocytoplasmic transport K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ... Nature 525 (7567), 56-61, 2015 | 1197 | 2015 |
| C9orf72 nucleotide repeat structures initiate molecular cascades of disease AR Haeusler, CJ Donnelly, G Periz, EAJ Simko, PG Shaw, MS Kim, ... Nature 507 (7491), 195-200, 2014 | 1164 | 2014 |
| RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ... Neuron 80 (2), 415-428, 2013 | 1127 | 2013 |
| The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease AR Haeusler, CJ Donnelly, JD Rothstein Nature Reviews Neuroscience 17 (6), 383-395, 2016 | 266 | 2016 |
| Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress T Westergard, K McAvoy, K Russell, X Wen, Y Pang, B Morris, P Pasinelli, ... EMBO molecular medicine 11 (2), e9423, 2019 | 139 | 2019 |
| G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA EAJ Simko, H Liu, T Zhang, A Velasquez, S Teli, AR Haeusler, J Wang Nucleic acids research 48 (13), 7421-7438, 2020 | 99 | 2020 |
| Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ALS/FTD is rescued by SV 2 replenishment BK Jensen, MH Schuldi, K McAvoy, KA Russell, A Boehringer, BM Curran, ... EMBO molecular medicine 12 (5), e10722, 2020 | 56 | 2020 |
| FRET studies of a landscape of Lac repressor-mediated DNA loops AR Haeusler, KA Goodson, TD Lillian, X Wang, S Goyal, NC Perkins, ... Nucleic acids research 40 (10), 4432-4445, 2012 | 46 | 2012 |
| Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration J Wang, AR Haeusler, EAJ Simko Cell Cycle 14 (4), 526-532, 2015 | 42 | 2015 |
| A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ... Scientific reports 12 (1), 5644, 2022 | 31 | 2022 |
| Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis‐linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice BK Jensen, KJ McAvoy, NM Heinsinger, AC Lepore, H Ilieva, ... Glia 70 (7), 1426-1449, 2022 | 21 | 2022 |
| Breakdown of the central synapses in C9orf72-linked ALS/FTD LT Ghaffari, D Trotti, AR Haeusler, BK Jensen Frontiers in Molecular Neuroscience 15, 1005112, 2022 | 20 | 2022 |
| LacI-DNA-IPTG loops: equilibria among conformations by single-molecule FRET KA Goodson, Z Wang, AR Haeusler, JD Kahn, DS English The Journal of Physical Chemistry B 117 (16), 4713-4722, 2013 | 19 | 2013 |
| The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion KA Ozcan, LT Ghaffari, AR Haeusler Scientific reports 11 (1), 23213, 2021 | 10 | 2021 |
| Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes AT Nelson, ME Cicardi, SS Markandaiah, JYS Han, NJ Philp, E Welebob, ... EMBO reports 25 (5), 2479-2510, 2024 | 9 | 2024 |
| The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly (GR) in C9orf72-linked ALS/FTD ME Cicardi, V Kankate, S Sriramoji, K Krishnamurthy, SS Markandaiah, ... Communications Biology 7 (1), 376, 2024 | 4 | 2024 |
| RNA G-Quadruplexes Function as a Tunable Switch of FUS Phase Separation JL Carey, M Hayashi, E Welebob, LR Ganser, H Wang, K Buckhaults, ... bioRxiv, 2025.10. 31.685846, 2025 | 2 | 2025 |
| Kapβ2 is a modifier of the C9orf72-linked glycine-arginine dipeptide neurotoxicity ME Cicardi, V Kankate, S Sriramoji, K Krishnamurthy, SS Markandaiah, ... bioRxiv, 2022.09. 30.510384, 2022 | 2 | 2022 |
| Differential response of C9orf72 transcripts following neuronal depolarization LT Ghaffari, D Trotti, AR Haeusler Iscience 26 (6), 2023 | 1 | 2023 |
| Neuronal activity-dependent gene dysregulation in C9orf72 i3Neuronal models of ALS/FTD pathogenesis LT Ghaffari, EA Welebob, SEB Newton, AV Boehringer, KL Cyliax, ... American Journal of Physiology-Cell Physiology 329 (4), C1085-C1100, 2025 | | 2025 |
