| Interleukin-6 receptor antagonists in critically ill patients with Covid-19 Remap-Cap Investigators New England Journal of Medicine 384 (16), 1491-1502, 2021 | 2164 | 2021 |
| Vasopressin versus norepinephrine infusion in patients with septic shock JA Russell, KR Walley, J Singer, AC Gordon, PC Hébert, DJ Cooper, ... New England Journal of Medicine 358 (9), 877-887, 2008 | 2105 | 2008 |
| Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis JAC Sterne, S Murthy, JV Diaz, AS Slutsky, J Villar, DC Angus, D Annane, ... Jama 324 (13), 1330-1341, 2020 | 2089 | 2020 |
| The artificial intelligence clinician learns optimal treatment strategies for sepsis in intensive care M Komorowski, LA Celi, O Badawi, AC Gordon, AA Faisal Nature medicine 24 (11), 1716-1720, 2018 | 1564 | 2018 |
| A minimal common outcome measure set for COVID-19 clinical research JC Marshall, S Murthy, J Diaz, NK Adhikari, DC Angus, YM Arabi, K Baillie, ... The lancet infectious diseases 20 (8), e192-e197, 2020 | 1309 | 2020 |
| DALI: defining antibiotic levels in intensive care unit patients: are current β-lactam antibiotic doses sufficient for critically ill patients? JA Roberts, SK Paul, M Akova, M Bassetti, JJ De Waele, G Dimopoulos, ... Clinical infectious diseases 58 (8), 1072-1083, 2014 | 1288 | 2014 |
| Therapeutic anticoagulation with heparin in noncritically ill patients with Covid-19 ATTACC, ACTIV-4a, and REMAP-CAP Investigators New England Journal of Medicine 385 (9), 790-802, 2021 | 1276 | 2021 |
| Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies M Nagendran, Y Chen, CA Lovejoy, AC Gordon, M Komorowski, ... bmj 368, 2020 | 1080 | 2020 |
| Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study EE Davenport, KL Burnham, J Radhakrishnan, P Humburg, P Hutton, ... The Lancet Respiratory Medicine 4 (4), 259-271, 2016 | 856 | 2016 |
| Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19: the REMAP-CAP COVID-19 corticosteroid domain randomized clinical trial DC Angus, L Derde, F Al-Beidh, D Annane, Y Arabi, A Beane, ... Jama 324 (13), 1317-1329, 2020 | 855 | 2020 |
| Effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock: the VANISH randomized clinical trial AC Gordon, AJ Mason, N Thirunavukkarasu, GD Perkins, M Cecconi, ... Jama 316 (5), 509-518, 2016 | 790 | 2016 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 610 | 2021 |
| Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis M Shankar-Hari, CL Vale, PJ Godolphin, D Fisher, JPT Higgins, F Spiga, ... Jama 326 (6), 1, 2021 | 507 | 2021 |
| Antimicrobial resistance and the United Nations sustainable development cooperation framework: Guidance for United Nations Country teams World Health Organization World Health Organization, 2021 | 493 | 2021 |
| The REMAP-CAP (randomized embedded multifactorial adaptive platform for community-acquired pneumonia) study. Rationale and design DC Angus, S Berry, RJ Lewis, F Al-Beidh, Y Arabi, W van Bentum-Puijk, ... Annals of the American Thoracic Society 17 (7), 879-891, 2020 | 443 | 2020 |
| Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials C Axfors, AM Schmitt, P Janiaud, J Van’t Hooft, S Abd-Elsalam, EF Abdo, ... Nature communications 12 (1), 2349, 2021 | 415 | 2021 |
| Levosimendan for the prevention of acute organ dysfunction in sepsis AC Gordon, GD Perkins, M Singer, DF McAuley, RML Orme, ... New England Journal of Medicine 375 (17), 1638-1648, 2016 | 415 | 2016 |
| Effect of reduced exposure to vasopressors on 90-day mortality in older critically ill patients with vasodilatory hypotension: a randomized clinical trial F Lamontagne, A Richards-Belle, K Thomas, DA Harrison, MZ Sadique, ... Jama 323 (10), 938-949, 2020 | 351 | 2020 |
| Redefining critical illness DM Maslove, B Tang, M Shankar-Hari, PR Lawler, DC Angus, JK Baillie, ... Nature medicine 28 (6), 1141-1148, 2022 | 339 | 2022 |
| Transcriptomic signatures in sepsis and a differential response to steroids. From the VANISH randomized trial DB Antcliffe, KL Burnham, F Al-Beidh, S Santhakumaran, SJ Brett, ... American journal of respiratory and critical care medicine 199 (8), 980-986, 2019 | 339 | 2019 |