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Ewen David Devaney Calder
Ewen David Devaney Calder
Chancellor's Fellow, University of Edinburgh
Verified email at ed.ac.uk
Title
Cited by
Cited by
Year
Clinical advances of hypoxia-activated prodrugs in combination with radiation therapy
IN Mistry, M Thomas, EDD Calder, SJ Conway, EM Hammond
International Journal of Radiation Oncology* Biology* Physics 98 (5), 1183-1196, 2017
1802017
Preparation of anti-Vicinal Amino Alcohols: Asymmetric Synthesis of d-erythro-Sphinganine, (+)-Spisulosine, and d-ribo-Phytosphingosine
EDD Calder, AM Zaed, A Sutherland
The Journal of Organic Chemistry 78 (14), 7223-7233, 2013
682013
Stereodivergent organocatalytic intramolecular Michael addition/lactonization for the asymmetric synthesis of substituted dihydrobenzofurans and tetrahydrofurans
D Belmessieri, A De La Houpliere, EDD Calder, JE Taylor, AD Smith
Chemistry–A European Journal 20 (31), 9762-9769, 2014
632014
Intermolecular Aryl C− H Amination through Sequential Iron and Copper Catalysis
MAB Mostafa, EDD Calder, DT Racys, A Sutherland
Chemistry–A European Journal 23 (5), 1044-1047, 2017
512017
Preparation of Amino-Substituted Indenes and 1,4-Dihydronaphthalenes Using a One-Pot Multireaction Approach: Total Synthesis of Oxybenzo[c]phenanthridine …
EDD Calder, FI McGonagle, AH Harkiss, GA McGonagle, A Sutherland
The Journal of Organic Chemistry 79 (16), 7633-7648, 2014
382014
One-pot multi-reaction processes: Synthesis of natural products and drug-like scaffolds
EDD Calder, MW Grafton, A Sutherland
Synlett 25 (08), 1068-1080, 2014
382014
Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor
A Skwarska, EDD Calder, D Sneddon, H Bolland, ML Odyniec, IN Mistry, ...
Cell chemical biology 28 (9), 1258-1270. e13, 2021
372021
Synthesis of 5-Amino-2,5-dihydro-1H-benzo[b]azepines Using a One-Pot Multibond Forming Process
SAI Sharif, EDD Calder, FG Delolo, A Sutherland
The Journal of Organic Chemistry 81 (15), 6697-6706, 2016
352016
One-Pot Synthesis of 5-Amino-2, 5-Dihydro-1-Benzoxepines: Access to Pharmacologically Active Heterocyclic Scaffolds
EDD Calder, SAI Sharif, FI McGonagle, A Sutherland
The Journal of organic chemistry 80, 4683, 2015
352015
Hypoxia-activated pro-drugs of the KDAC inhibitor vorinostat (SAHA)
EDD Calder, A Skwarska, D Sneddon, LK Folkes, IN Mistry, SJ Conway, ...
Tetrahedron 76 (21), 131170, 2020
282020
Enantioselective Synthesis of 3-Methyleneindan-1-Ols via a One-Pot Allylboration–Heck Reaction of 2-Bromobenzaldehydes
EDD Calder, A Sutherland
Organic Letters 17 (10), 2514-2517, 2015
222015
Low temperature capture of pseudorotaxanes
NI Hassan, V Del Amo, E Calder, D Philp
Organic Letters 13 (3), 458-461, 2011
222011
Strategies to expand peptide functionality through hybridisation with a small molecule component
Y Wu, J Williams, EDD Calder, LJ Walport
RSC Chemical Biology 2 (1), 151-165, 2021
212021
Synthesis of Allylic Amide Functionalized 2H-Chromenes and Coumarins Using a One-Pot Overman Rearrangement and Gold(I)-Catalyzed Hydroarylation
SAI Sharif, EDD Calder, AH Harkiss, M Maduro, A Sutherland
The Journal of Organic Chemistry 81 (20), 9810-9819, 2016
182016
Discovering covalent cyclic peptide inhibitors of peptidyl arginine deiminase 4 (PADI4) using mRNA-display with a genetically encoded electrophilic warhead
IR Mathiesen, EDD Calder, S Kunzelmann, LJ Walport
Communications Chemistry 7 (1), 304, 2024
142024
Zap‐Pano: a Photocaged Prodrug of the KDAC Inhibitor Panobinostat
KS Troelsen, EDD Calder, A Skwarska, D Sneddon, EM Hammond, ...
ChemMedChem 16 (24), 3691-3700, 2021
112021
One-Pot Asymmetric Synthesis of Alkylidene 1-Alkylindan-1-ols Using Brønsted Acid and Palladium Catalysis
RJ Faggyas, EDD Calder, C Wilson, A Sutherland
The Journal of Organic Chemistry 82 (21), 11585-11593, 2017
112017
Characterization of HSP90 isoforms in transformed bovine leukocytes infected with Theileria annulata
JH Kinnaird, M Singh, V Gillan, W Weir, EDD Calder, I Hostettler, U Tatu, ...
Cellular microbiology 19 (3), e12669, 2017
112017
Fluorescent Amino Acid Initiated de novo Cyclic Peptides for the Label‐Free Assessment of Cell Permeability**
Y Wu, MT Bertran, J Rowley, EDD Calder, D Joshi, LJ Walport
ChemMedChem 16 (20), 3185-3188, 2021
72021
Indolequinone-based hypoxia-activated proteolysis targeting chimeras selectively degrade BRD4 in hypoxic Cancer cells
M Serafini, SA Twigger, G Delfas, M Mallerman, EP Bailey, EDD Calder, ...
Journal of the American Chemical Society 147 (40), 36352-36364, 2025
52025
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Articles 1–20