| Model-based analysis of ChIP-Seq (MACS) Y Zhang, T Liu, CA Meyer, J Eeckhoute, DS Johnson, BE Bernstein, ... Genome biology 9 (9), R137, 2008 | 19536 | 2008 |
| An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium Nature 489 (7414), 57, 2012 | 18916 | 2012 |
| Comprehensive mapping of long-range interactions reveals folding principles of the human genome E Lieberman-Aiden, NL Van Berkum, L Williams, M Imakaev, T Ragoczy, ... science 326 (5950), 289-293, 2009 | 10109 | 2009 |
| Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, P Kheradpour, ... Nature 518 (7539), 317, 2015 | 7045 | 2015 |
| A bivalent chromatin structure marks key developmental genes in embryonic stem cells BE Bernstein, TS Mikkelsen, X Xie, M Kamal, DJ Huebert, J Cuff, B Fry, ... Cell 125 (2), 315-326, 2006 | 6663 | 2006 |
| Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ... Science 344 (6190), 1396-1401, 2014 | 5483 | 2014 |
| Genome-wide maps of chromatin state in pluripotent and lineage-committed cells TS Mikkelsen, M Ku, DB Jaffe, B Issac, E Lieberman, G Giannoukos, ... Nature 448 (7153), 553-560, 2007 | 5183 | 2007 |
| Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ... Nature 458 (7235), 223-227, 2009 | 5048 | 2009 |
| In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state M Wernig, A Meissner, R Foreman, T Brambrink, M Ku, K Hochedlinger, ... nature 448 (7151), 318-324, 2007 | 3628 | 2007 |
| Mapping and analysis of chromatin state dynamics in nine human cell types J Ernst, P Kheradpour, TS Mikkelsen, N Shoresh, LD Ward, CB Epstein, ... Nature 473 (7345), 43-49, 2011 | 3502 | 2011 |
| Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression AM Khalil, M Guttman, M Huarte, M Garber, A Raj, D Rivea Morales, ... Proceedings of the National Academy of Sciences 106 (28), 11667-11672, 2009 | 3464 | 2009 |
| Genome-scale DNA methylation maps of pluripotent and differentiated cells A Meissner, TS Mikkelsen, H Gu, M Wernig, J Hanna, A Sivachenko, ... Nature 454 (7205), 766-770, 2008 | 3133 | 2008 |
| The mammalian epigenome BE Bernstein, A Meissner, ES Lander Cell 128 (4), 669-681, 2007 | 2966 | 2007 |
| Active genes are tri-methylated at K4 of histone H3 H Santos-Rosa, R Schneider, AJ Bannister, J Sherriff, BE Bernstein, ... Nature 419 (6905), 407-411, 2002 | 2797 | 2002 |
| An integrative model of cellular states, plasticity, and genetics for glioblastoma C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ... Cell 178 (4), 835-849. e21, 2019 | 2659 | 2019 |
| Single-cell transcriptomic analysis of primary and metastatic tumor ecosystems in head and neck cancer SV Puram, I Tirosh, AS Parikh, AP Patel, K Yizhak, S Gillespie, C Rodman, ... Cell 171 (7), 1611-1624. e24, 2017 | 2528 | 2017 |
| ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia SG Landt, GK Marinov, A Kundaje, P Kheradpour, F Pauli, S Batzoglou, ... Genome research 22 (9), 1813-1831, 2012 | 2524 | 2012 |
| Genetic and epigenetic fine mapping of causal autoimmune disease variants KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ... Nature 518 (7539), 337-343, 2015 | 2224 | 2015 |
| The NIH roadmap epigenomics mapping consortium BE Bernstein, JA Stamatoyannopoulos, JF Costello, B Ren, ... Nature biotechnology 28 (10), 1045-1048, 2010 | 2096 | 2010 |
| Cohesin loss eliminates all loop domains SSP Rao, SC Huang, BG St Hilaire, JM Engreitz, EM Perez, ... Cell 171 (2), 305-320. e24, 2017 | 2067 | 2017 |