| BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia MS Zabriskie, CA Eide, SK Tantravahi, NA Vellore, J Estrada, FE Nicolini, ... Cancer cell 26 (3), 428-442, 2014 | 401 | 2014 |
| Membrane protein structure, function, and dynamics: a perspective from experiments and theory Z Cournia, TW Allen, I Andricioaei, B Antonny, D Baum, G Brannigan, ... The Journal of membrane biology 248 (4), 611-640, 2015 | 298 | 2015 |
| Wordom: a user‐friendly program for the analysis of molecular structures, trajectories, and free energy surfaces M Seeber, A Felline, F Raimondi, S Muff, R Friedman, F Rao, A Caflisch, ... Journal of computational chemistry 32 (6), 1183-1194, 2011 | 283 | 2011 |
| Amyloid aggregation on lipid bilayers and its impact on membrane permeability R Friedman, R Pellarin, A Caflisch Journal of molecular biology 387 (2), 407-415, 2009 | 165 | 2009 |
| Terahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein crystal IV Lundholm, H Rodilla, WY Wahlgren, A Duelli, G Bourenkov, J Vukusic, ... Structural Dynamics 2 (5), 2015 | 140 | 2015 |
| Drug resistance in cancer: molecular evolution and compensatory proliferation R Friedman Oncotarget 7 (11), 11746, 2016 | 97 | 2016 |
| Molecular dynamics of a protein surface: ion-residues interactions R Friedman, E Nachliel, M Gutman Biophysical journal 89 (2), 768-781, 2005 | 83 | 2005 |
| Molecular modelling and simulations in cancer research R Friedman, K Boye, K Flatmark Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1836 (1), 1-14, 2013 | 82 | 2013 |
| Discovery of plasmepsin inhibitors by fragment‐based docking and consensus scoring R Friedman, A Caflisch ChemMedChem 4 (8), 1317-1326, 2009 | 81 | 2009 |
| Computational studies of protein–drug binding affinity changes upon mutations in the drug target R Friedman Wiley Interdisciplinary Reviews: Computational Molecular Science 12 (1), e1563, 2022 | 65 | 2022 |
| Dilution of whisky–the molecular perspective BCG Karlsson, R Friedman Scientific reports 7 (1), 6489, 2017 | 65 | 2017 |
| Aggregation of amyloids in a cellular context: modelling and experiment R Friedman Biochemical Journal 438 (3), 415-426, 2011 | 58 | 2011 |
| Fatty acid binding proteins: same structure but different binding mechanisms? Molecular dynamics simulations of intestinal fatty acid binding protein R Friedman, E Nachliel, M Gutman Biophysical journal 90 (5), 1535-1545, 2006 | 57 | 2006 |
| A molecular dynamics study and free energy analysis of complexes between the Mlc1p protein and two IQ motif peptides A Ganoth, R Friedman, E Nachliel, M Gutman Biophysical journal 91 (7), 2436-2450, 2006 | 52 | 2006 |
| Multistep orthophosphate release tunes actomyosin energy transduction L Moretto, M Ušaj, O Matusovsky, DE Rassier, R Friedman, A Månsson Nature communications 13 (1), 4575, 2022 | 50 | 2022 |
| Molecular dynamics simulations of palmitate entry into the hydrophobic pocket of the fatty acid binding protein Y Tsfadia, R Friedman, J Kadmon, A Selzer, E Nachliel, M Gutman Febs Letters 581 (6), 1243-1247, 2007 | 50 | 2007 |
| The molecular mechanisms behind activation of FLT3 in acute myeloid leukemia and resistance to therapy by selective inhibitors R Friedman Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1877 (1), 188666, 2022 | 47 | 2022 |
| Membrane–ion interactions R Friedman The Journal of membrane biology 251 (3), 453-460, 2018 | 47 | 2018 |
| Ions and the protein surface revisited: extensive molecular dynamics simulations and analysis of protein structures in alkali-chloride solutions R Friedman The Journal of Physical Chemistry B 115 (29), 9213-9223, 2011 | 47 | 2011 |
| Acute Toxicity-Supported Chronic Toxicity Prediction: A k-Nearest Neighbor Coupled Read-Across Strategy S Chavan, R Friedman, IA Nicholls International journal of molecular sciences 16 (5), 11659-11677, 2015 | 46 | 2015 |
