| Proteoform: a single term describing protein complexity LM Smith, NL Kelleher Nature methods 10 (3), 186-187, 2013 | 1450 | 2013 |
| How many human proteoforms are there? R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ... Nature chemical biology 14 (3), 206-214, 2018 | 1091 | 2018 |
| Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS DA Bosco, G Morfini, NM Karabacak, Y Song, F Gros-Louis, P Pasinelli, ... Nature neuroscience 13 (11), 1396-1403, 2010 | 877 | 2010 |
| A soluble α-synuclein construct forms a dynamic tetramer W Wang, I Perovic, J Chittuluru, A Kaganovich, LTT Nguyen, J Liao, ... Proceedings of the National Academy of Sciences 108 (43), 17797-17802, 2011 | 642 | 2011 |
| IscU as a scaffold for iron− sulfur cluster biosynthesis: sequential assembly of [2Fe-2S] and [4Fe-4S] clusters in IscU JN Agar, C Krebs, J Frazzon, BH Huynh, DR Dean, MK Johnson Biochemistry 39 (27), 7856-7862, 2000 | 563 | 2000 |
| Best practices and benchmarks for intact protein analysis for top-down mass spectrometry DP Donnelly, CM Rawlins, CJ DeHart, L Fornelli, LF Schachner, Z Lin, ... Nature methods 16 (7), 587-594, 2019 | 428 | 2019 |
| NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein P Yuvaniyama, JN Agar, VL Cash, MK Johnson, DR Dean Proceedings of the National Academy of Sciences 97 (2), 599-604, 2000 | 428 | 2000 |
| Fitting neurological protein aggregation kinetic data via a 2-step, Minimal/“Ockham's Razor” Model: The Finke− Watzky mechanism of nucleation followed by autocatalytic surface … AM Morris, MA Watzky, JN Agar, RG Finke Biochemistry 47 (8), 2413-2427, 2008 | 365 | 2008 |
| IscA, an alternate scaffold for Fe− S cluster biosynthesis C Krebs, JN Agar, AD Smith, J Frazzon, DR Dean, BH Huynh, ... Biochemistry 40 (46), 14069-14080, 2001 | 327 | 2001 |
| Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency H Antonicka, SC Leary, GH Guercin, JN Agar, R Horvath, NG Kennaway, ... Human molecular genetics 12 (20), 2693-2702, 2003 | 323 | 2003 |
| Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival Q Wang, JL Johnson, NYR Agar, JN Agar PLoS biology 6 (7), e170, 2008 | 283 | 2008 |
| The human proteoform project: defining the human proteome LM Smith, JN Agar, J Chamot-Rooke, PO Danis, Y Ge, JA Loo, ... Science advances 7 (46), eabk0734, 2021 | 243 | 2021 |
| Sulfur transfer from IscS to IscU: the first step in iron− sulfur cluster biosynthesis AD Smith, JN Agar, KA Johnson, J Frazzon, IJ Amster, DR Dean, ... Journal of the american chemical society 123 (44), 11103-11104, 2001 | 240 | 2001 |
| Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis E Kabashi, JN Agar, DM Taylor, S Minotti, HD Durham Journal of neurochemistry 89 (6), 1325-1335, 2004 | 197 | 2004 |
| An international laboratory comparison of dissolved organic matter composition by high resolution mass spectrometry: Are we getting the same answer? JA Hawkes, J d'Andrilli, JN Agar, MP Barrow, SM Berg, N Catalán, ... Limnology and Oceanography: Methods 18 (6), 235-258, 2020 | 191 | 2020 |
| NifS-mediated assembly of [4Fe− 4S] clusters in the N-and C-terminal domains of the NifU scaffold protein AD Smith, GNL Jameson, PC Dos Santos, JN Agar, S Naik, C Krebs, ... Biochemistry 44 (39), 12955-12969, 2005 | 185 | 2005 |
| Modular organization and identification of a mononuclear iron-binding site within the NifU protein JN Agar, P Yuvaniyama, RF Jack, VL Cash, AD Smith, DR Dean, ... JBIC Journal of Biological Inorganic Chemistry 5 (2), 167-177, 2000 | 176 | 2000 |
| Role of the IscU Protein in Iron−Sulfur Cluster Biosynthesis: IscS-mediated Assembly of a [Fe2S2] Cluster in IscU JN Agar, L Zheng, VL Cash, DR Dean, MK Johnson Journal of the american chemical society 122 (9), 2136-2137, 2000 | 156 | 2000 |
| Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging X Liu, JL Ide, I Norton, MA Marchionni, MC Ebling, LY Wang, E Davis, ... Scientific reports 3 (1), 2859, 2013 | 146 | 2013 |
| Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact KJ Boggio, E Obasuyi, K Sugino, SB Nelson, NYR Agar, JN Agar Expert review of proteomics 8 (5), 591-604, 2011 | 139 | 2011 |
Dennis DeanDepartment of Biochemistry, University Distinguished Professor, Virginia TechVerified email at vt.edu
