| CNVkit: genome-wide copy number detection and visualization from targeted DNA sequencing E Talevich, AH Shain, T Botton, BC Bastian PLoS computational biology 12 (4), e1004873, 2016 | 2171 | 2016 |
| The genetic evolution of melanoma from precursor lesions AH Shain, I Yeh, I Kovalyshyn, A Sriharan, E Talevich, A Gagnon, ... New England Journal of Medicine 373 (20), 1926-1936, 2015 | 1303 | 2015 |
| From melanocytes to melanomas AH Shain, BC Bastian nature reviews Cancer 16 (6), 345-358, 2016 | 1152 | 2016 |
| The spectrum of SWI/SNF mutations, ubiquitous in human cancers AH Shain, JR Pollack PloS one 8 (1), e55119, 2013 | 711 | 2013 |
| Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism K Chiba, FK Lorbeer, AH Shain, DT McSwiggen, E Schruf, A Oh, J Ryu, ... Science 357 (6358), 1416-1420, 2017 | 331 | 2017 |
| Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway AH Shain, M Garrido, T Botton, E Talevich, I Yeh, JZ Sanborn, J Chung, ... Nature genetics 47 (10), 1194-1199, 2015 | 299 | 2015 |
| Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer AH Shain, CP Giacomini, K Matsukuma, CA Karikari, MD Bashyam, ... Proceedings of the National Academy of Sciences 109 (5), E252-E259, 2012 | 285 | 2012 |
| Activating MET kinase rearrangements in melanoma and Spitz tumours I Yeh, T Botton, E Talevich, AH Shain, AJ Sparatta, A De La Fouchardiere, ... Nature communications 6 (1), 7174, 2015 | 263 | 2015 |
| The genetic evolution of metastatic uveal melanoma AH Shain, MM Bagger, R Yu, D Chang, S Liu, S Vemula, JF Weier, ... Nature genetics 51 (7), 1123-1130, 2019 | 239 | 2019 |
| Genomic and transcriptomic analysis reveals incremental disruption of key signaling pathways during melanoma evolution AH Shain, NM Joseph, R Yu, J Benhamida, S Liu, T Prow, B Ruben, ... Cancer cell 34 (1), 45-55. e4, 2018 | 238 | 2018 |
| Targeted genomic profiling of acral melanoma I Yeh, E Jorgenson, L Shen, M Xu, JP North, AH Shain, D Reuss, H Wu, ... JNCI: Journal of the National Cancer Institute 111 (10), 1068-1077, 2019 | 197 | 2019 |
| NTRK3 kinase fusions in Spitz tumours I Yeh, MK Tee, T Botton, AH Shain, AJ Sparatta, A Gagnon, SS Vemula, ... The Journal of pathology 240 (3), 282-290, 2016 | 166 | 2016 |
| A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma J Pozniak, D Pedri, E Landeloos, Y Van Herck, A Antoranz, ... Cell 187 (1), 166-183. e25, 2024 | 160 | 2024 |
| Bi-allelic loss of CDKN2A initiates melanoma invasion via BRN2 activation H Zeng, A Jorapur, AH Shain, UE Lang, R Torres, Y Zhang, AS McNeal, ... Cancer cell 34 (1), 56-68. e9, 2018 | 154 | 2018 |
| Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi I Yeh, UE Lang, E Durieux, MK Tee, A Jorapur, AH Shain, V Haddad, ... Nature communications 8 (1), 644, 2017 | 149 | 2017 |
| The genomic landscapes of individual melanocytes from human skin J Tang, E Fewings, D Chang, H Zeng, S Liu, A Jorapur, RL Belote, ... Nature 586 (7830), 600-605, 2020 | 143 | 2020 |
| Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types CP Giacomini, S Sun, S Varma, AH Shain, MM Giacomini, J Balagtas, ... PLoS genetics 9 (4), e1003464, 2013 | 137 | 2013 |
| The landscape of driver mutations in cutaneous squamous cell carcinoma D Chang, AH Shain NPJ genomic medicine 6 (1), 61, 2021 | 135 | 2021 |
| Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host WW Tseng, D Winer, JA Kenkel, O Choi, AH Shain, JR Pollack, R French, ... Clinical Cancer Research 16 (14), 3684-3695, 2010 | 131 | 2010 |
| Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma W Cao, H Lee, W Wu, A Zaman, S McCorkle, M Yan, J Chen, Q Xing, ... Nature communications 11 (1), 3675, 2020 | 129 | 2020 |
Boris BastianProfessor of Dermatology and Pathology, University of California, San FranciscoVerified email at ucsf.edu
