| Conformations of immunoglobulin hypervariable regions C Chothia, AM Lesk, A Tramontano, M Levitt, SJ Smith-Gill, G Air, S Sheriff, ... Nature 342 (6252), 877-883, 1989 | 2044 | 1989 |
| Mitochondrial release of caspase-2 and-9 during the apoptotic process SA Susin, HK Lorenzo, N Zamzami, I Marzo, C Brenner, N Larochette, ... The Journal of experimental medicine 189 (2), 381-394, 1999 | 967 | 1999 |
| Missense mutations in the catalase‐peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis B Heym, PM Alzari, N Honore, ST Cole Molecular microbiology 15 (2), 235-245, 1995 | 484 | 1995 |
| Three-dimensional structure of antibodies PM Alzari, MB Lascombe, RJ Poljak Annual review of immunology 6 (1), 555-580, 1988 | 435 | 1988 |
| Structural Basis of Antigen-16 A Antibody Recognition RA Mariuzza, PM Alzari, AG Amit, G Bentley, G Boulot, V Chitarra, ... Use of X-ray Crystallography in the Design of Antiviral Agents, 203, 1990 | 417 | 1990 |
| Interleukin 2 and its receptors: recent advances and new immunological functions J Thèze, PM Alzari, J Bertoglio Immunology Today 17 (10), 481-486, 1996 | 332 | 1996 |
| The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis A Buschiazzo, MF Amaya, ML Cremona, AC Frasch, PM Alzari Molecular cell 10 (4), 757-768, 2002 | 309 | 2002 |
| Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile AG Watts, I Damager, ML Amaya, A Buschiazzo, P Alzari, AC Frasch, ... Journal of the American Chemical Society 125 (25), 7532-7533, 2003 | 297 | 2003 |
| Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase MF Amaya, AG Watts, I Damager, A Wehenkel, T Nguyen, A Buschiazzo, ... Structure 12 (5), 775-784, 2004 | 279 | 2004 |
| Three-dimensional structure of a thermostable bacterial cellulase M Juy, AG Amrt, PM Alzari, RJ Poljak, M Claeyssens, P Béguin, JP Aubert Nature 357 (6373), 89-91, 1992 | 278 | 1992 |
| The three-dimensional structure of the aspartyl protease from the HIV-1 isolate BRU S Spinelli, QZ Liu, PM Alzari, PH Hirel, RJ Poljak Biochimie 73 (11), 1391-1396, 1991 | 268 | 1991 |
| The crystal structure of the mouse apoptosis-inducing factor AIF MJ Maté, M Ortiz-Lombardía, B Boitel, A Haouz, D Tello, SA Susin, ... Nature structural biology 9 (6), 442-446, 2002 | 263 | 2002 |
| Structural plasticity and catalysis regulation of a thermosensor histidine kinase D Albanesi, M Martin, F Trajtenberg, MC Mansilla, A Haouz, PM Alzari, ... Proceedings of the National Academy of Sciences 106 (38), 16185-16190, 2009 | 257 | 2009 |
| The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth P Fernandez, B Saint-Joanis, N Barilone, M Jackson, B Gicquel, ST Cole, ... Journal of bacteriology 188 (22), 7778-7784, 2006 | 240 | 2006 |
| The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum PM Alzari, H ne Souchon, R Dominguez Structure 4 (3), 265-275, 1996 | 228 | 1996 |
| A common protein fold and similar active site in two distinct families of β-glycanases R Dominguez, H Souchon, S Spinelli, Z Dauter, KS Wilson, S Chauvaux, ... Nature structural biology 2 (7), 569-576, 1995 | 224 | 1995 |
| Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential A Wehenkel, M Bellinzoni, M Graña, R Duran, A Villarino, P Fernandez, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (1), 193-202, 2008 | 223 | 2008 |
| PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho‐Ser/Thr phosphatase, in Mycobacterium tuberculosis B Boitel, M Ortiz‐Lombardía, R Durán, F Pompeo, ST Cole, ... Molecular microbiology 49 (6), 1493-1508, 2003 | 220 | 2003 |
| Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation A Buschiazzo, JE Ugalde, ME Guerin, W Shepard, RA Ugalde, PM Alzari The EMBO journal 23 (16), 3196-3205, 2004 | 216 | 2004 |
| The protein encoded by a murine male germ cell-specific transcript is a putative ATP-dependent RNA helicase P Leroy, P Alzari, D Sassoon, D Wolgemuth, M Fellous Cell 57 (4), 549-559, 1989 | 213 | 1989 |
